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Journal Abstract Search

284 related items for PubMed ID: 7499212

  • 1. TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.
    Lorenz MC, Heitman J.
    J Biol Chem; 1995 Nov 17; 270(46):27531-7. PubMed ID: 7499212
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  • 2. Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue.
    Stan R, McLaughlin MM, Cafferkey R, Johnson RK, Rosenberg M, Livi GP.
    J Biol Chem; 1994 Dec 23; 269(51):32027-30. PubMed ID: 7528205
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  • 6. Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity.
    Cafferkey R, Young PR, McLaughlin MM, Bergsma DJ, Koltin Y, Sathe GM, Faucette L, Eng WK, Johnson RK, Livi GP.
    Mol Cell Biol; 1993 Oct 23; 13(10):6012-23. PubMed ID: 8413204
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  • 9. RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.
    Sabatini DM, Erdjument-Bromage H, Lui M, Tempst P, Snyder SH.
    Cell; 1994 Jul 15; 78(1):35-43. PubMed ID: 7518356
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  • 10. FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast.
    Kunz J, Loeschmann A, Deuter-Reinhard M, Hall MN.
    Mol Microbiol; 2000 Sep 15; 37(6):1480-93. PubMed ID: 10998178
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  • 14. RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex.
    Chiu MI, Katz H, Berlin V.
    Proc Natl Acad Sci U S A; 1994 Dec 20; 91(26):12574-8. PubMed ID: 7809080
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  • 17. High-sensitivity sequencing of large proteins: partial structure of the rapamycin-FKBP12 target.
    Erdjument-Bromage H, Lui M, Sabatini DM, Snyder SH, Tempst P.
    Protein Sci; 1994 Dec 20; 3(12):2435-46. PubMed ID: 7756997
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  • 18. Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR.
    Cruz MC, Goldstein AL, Blankenship J, Del Poeta M, Perfect JR, McCusker JH, Bennani YL, Cardenas ME, Heitman J.
    Antimicrob Agents Chemother; 2001 Nov 20; 45(11):3162-70. PubMed ID: 11600372
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  • 19. Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans.
    Cruz MC, Cavallo LM, Görlach JM, Cox G, Perfect JR, Cardenas ME, Heitman J.
    Mol Cell Biol; 1999 Jun 20; 19(6):4101-12. PubMed ID: 10330150
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  • 20. The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine.
    Weisman R, Choder M.
    J Biol Chem; 2001 Mar 09; 276(10):7027-32. PubMed ID: 11096119
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