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194 related items for PubMed ID: 7499389

  • 1. Defective glycolysis and calcium signaling underlie impaired insulin secretion in a transgenic mouse.
    Ribar TJ, Jan CR, Augustine GJ, Means AR.
    J Biol Chem; 1995 Dec 01; 270(48):28688-95. PubMed ID: 7499389
    [Abstract] [Full Text] [Related]

  • 2. Alterations in calcium channel currents underlie defective insulin secretion in a transgenic mouse.
    Jan CR, Ribar TJ, Means AR, Augustine GJ.
    J Biol Chem; 1996 Jun 28; 271(26):15478-85. PubMed ID: 8663103
    [Abstract] [Full Text] [Related]

  • 3. Glucose regulation of insulin secretion independent of the opening or closure of adenosine triphosphate-sensitive K+ channels in beta cells.
    Sato Y, Anello M, Henquin JC.
    Endocrinology; 1999 May 28; 140(5):2252-7. PubMed ID: 10218978
    [Abstract] [Full Text] [Related]

  • 4. Involvement of calmodulin in glucagon-like peptide 1(7-36) amide-induced inhibition of the ATP-sensitive K+ channel in mouse pancreatic beta-cells.
    Ding WG, Kitasato H, Matsuura H.
    Exp Physiol; 2001 May 28; 86(3):331-9. PubMed ID: 11429650
    [Abstract] [Full Text] [Related]

  • 5. Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.
    Ravier MA, Nenquin M, Miki T, Seino S, Henquin JC.
    Endocrinology; 2009 Jan 28; 150(1):33-45. PubMed ID: 18787024
    [Abstract] [Full Text] [Related]

  • 6. Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.
    Nenquin M, Szollosi A, Aguilar-Bryan L, Bryan J, Henquin JC.
    J Biol Chem; 2004 Jul 30; 279(31):32316-24. PubMed ID: 15175349
    [Abstract] [Full Text] [Related]

  • 7. Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.
    Straub SG, Cosgrove KE, Ammälä C, Shepherd RM, O'Brien RE, Barnes PD, Kuchinski N, Chapman JC, Schaeppi M, Glaser B, Lindley KJ, Sharp GW, Aynsley-Green A, Dunne MJ.
    Diabetes; 2001 Feb 30; 50(2):329-39. PubMed ID: 11272144
    [Abstract] [Full Text] [Related]

  • 8. Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice.
    Dukes ID, Sreenan S, Roe MW, Levisetti M, Zhou YP, Ostrega D, Bell GI, Pontoglio M, Yaniv M, Philipson L, Polonsky KS.
    J Biol Chem; 1998 Sep 18; 273(38):24457-64. PubMed ID: 9733737
    [Abstract] [Full Text] [Related]

  • 9. Electrophysiological and metabolic characterization of single beta-cells and islets from diabetic GK rats.
    Hughes SJ, Faehling M, Thorneley CW, Proks P, Ashcroft FM, Smith PA.
    Diabetes; 1998 Jan 18; 47(1):73-81. PubMed ID: 9421377
    [Abstract] [Full Text] [Related]

  • 10. Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels.
    Rorsman P, Arkhammar P, Bokvist K, Hellerström C, Nilsson T, Welsh M, Welsh N, Berggren PO.
    Proc Natl Acad Sci U S A; 1989 Jun 18; 86(12):4505-9. PubMed ID: 2543980
    [Abstract] [Full Text] [Related]

  • 11. Effects of caffeine on cytoplasmic free Ca2+ concentration in pancreatic beta-cells are mediated by interaction with ATP-sensitive K+ channels and L-type voltage-gated Ca2+ channels but not the ryanodine receptor.
    Islam MS, Larsson O, Nilsson T, Berggren PO.
    Biochem J; 1995 Mar 15; 306 ( Pt 3)(Pt 3):679-86. PubMed ID: 7702559
    [Abstract] [Full Text] [Related]

  • 12. Glucagon induces suppression of ATP-sensitive K+ channel activity through a Ca2+/calmodulin-dependent pathway in mouse pancreatic beta-cells.
    He LP, Mears D, Atwater I, Kitasato H.
    J Membr Biol; 1998 Dec 01; 166(3):237-44. PubMed ID: 9843597
    [Abstract] [Full Text] [Related]

  • 13. ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
    Chapman JC, McClenaghan NH, Cosgrove KE, Hashmi MN, Shepherd RM, Giesberts AN, White SJ, Ammälä C, Flatt PR, Dunne MJ.
    Diabetes; 1999 Dec 01; 48(12):2349-57. PubMed ID: 10580423
    [Abstract] [Full Text] [Related]

  • 14. Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. II. Electrophysiological and fluorimetric studies.
    Rustenbeck I, Dickel C, Grimmsmanns T.
    Biochem Pharmacol; 2001 Dec 15; 62(12):1695-703. PubMed ID: 11755123
    [Abstract] [Full Text] [Related]

  • 15. Targeted overexpression of an inactive calmodulin that binds Ca2+ to the mouse pancreatic beta-cell results in impaired secretion and chronic hyperglycemia.
    Ribar TJ, Epstein PN, Overbeek PA, Means AR.
    Endocrinology; 1995 Jan 15; 136(1):106-15. PubMed ID: 7828519
    [Abstract] [Full Text] [Related]

  • 16. Triggering and amplifying pathways of regulation of insulin secretion by glucose.
    Henquin JC.
    Diabetes; 2000 Nov 15; 49(11):1751-60. PubMed ID: 11078440
    [Abstract] [Full Text] [Related]

  • 17. Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal.
    Szollosi A, Nenquin M, Henquin JC.
    J Biol Chem; 2007 May 18; 282(20):14768-76. PubMed ID: 17389589
    [Abstract] [Full Text] [Related]

  • 18. Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signaling pathways in human islets.
    Straub SG, James RF, Dunne MJ, Sharp GW.
    Diabetes; 1998 May 18; 47(5):758-63. PubMed ID: 9588447
    [Abstract] [Full Text] [Related]

  • 19. Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells.
    Nakazaki M, Kakei M, Ishihara H, Koriyama N, Hashiguchi H, Aso K, Fukudome M, Oka Y, Yada T, Tei C.
    J Physiol; 2002 May 01; 540(Pt 3):781-9. PubMed ID: 11986368
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.
    MacDonald PE, Sewing S, Wang J, Joseph JW, Smukler SR, Sakellaropoulos G, Wang J, Saleh MC, Chan CB, Tsushima RG, Salapatek AM, Wheeler MB.
    J Biol Chem; 2002 Nov 22; 277(47):44938-45. PubMed ID: 12270920
    [Abstract] [Full Text] [Related]

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