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3. Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate. Tai CH, Yoon MY, Kim SK, Rege VD, Nalabolu SR, Kredich NM, Schnackerz KD, Cook PF. Biochemistry; 1998 Jul 28; 37(30):10597-604. PubMed ID: 9692949 [Abstract] [Full Text] [Related]
5. Role of Histidine-152 in cofactor orientation in the PLP-dependent O-acetylserine sulfhydrylase reaction. Tai CH, Rabeh WM, Guan R, Schnackerz KD, Cook PF. Arch Biochem Biophys; 2008 Apr 15; 472(2):115-25. PubMed ID: 18275838 [Abstract] [Full Text] [Related]
6. Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes. Chattopadhyay A, Meier M, Ivaninskii S, Burkhard P, Speroni F, Campanini B, Bettati S, Mozzarelli A, Rabeh WM, Li L, Cook PF. Biochemistry; 2007 Jul 17; 46(28):8315-30. PubMed ID: 17583914 [Abstract] [Full Text] [Related]
7. Product binding to the alpha-carboxyl subsite results in a conformational change at the active site of O-acetylserine sulfhydrylase-A: evidence from fluorescence spectroscopy. McClure GD, Cook PF. Biochemistry; 1994 Feb 22; 33(7):1674-83. PubMed ID: 8110769 [Abstract] [Full Text] [Related]
8. Phosphonate and alpha-fluorophosphonate analogue probes of the ionization state of pyridoxal 5'-phosphate (PLP) in glycogen phosphorylase. Stirtan WG, Withers SG. Biochemistry; 1996 Nov 26; 35(47):15057-64. PubMed ID: 8942672 [Abstract] [Full Text] [Related]
9. Substitution of pyridoxal 5'-phosphate in the O-acetylserine sulfhydrylase from Salmonella typhimurium by cofactor analogs provides a test of the mechanism proposed for formation of the alpha-aminoacrylate intermediate. Cook PF, Tai CH, Hwang CC, Woehl EU, Dunn MF, Schnackerz KD. J Biol Chem; 1996 Oct 18; 271(42):25842-9. PubMed ID: 8824215 [Abstract] [Full Text] [Related]
10. Role of Arg-277 in the binding of pyridoxal 5'-phosphate to Trypanosoma brucei ornithine decarboxylase. Osterman AL, Brooks HB, Rizo J, Phillips MA. Biochemistry; 1997 Apr 15; 36(15):4558-67. PubMed ID: 9109665 [Abstract] [Full Text] [Related]
11. Tryptophan luminescence as a probe of enzyme conformation along the O-acetylserine sulfhydrylase reaction pathway. Strambini GB, Cioni P, Cook PF. Biochemistry; 1996 Jun 25; 35(25):8392-400. PubMed ID: 8679597 [Abstract] [Full Text] [Related]
12. Formation of the alpha-aminoacrylate immediate limits the overall reaction catalyzed by O-acetylserine sulfhydrylase. Woehl EU, Tai CH, Dunn MF, Cook PF. Biochemistry; 1996 Apr 16; 35(15):4776-83. PubMed ID: 8664267 [Abstract] [Full Text] [Related]
13. Role of the pyridine nitrogen in pyridoxal 5'-phosphate catalysis: activity of three classes of PLP enzymes reconstituted with deazapyridoxal 5'-phosphate. Griswold WR, Toney MD. J Am Chem Soc; 2011 Sep 21; 133(37):14823-30. PubMed ID: 21827189 [Abstract] [Full Text] [Related]
14. Identification of the structural determinants for the stability of substrate and aminoacrylate external Schiff bases in O-acetylserine sulfhydrylase-A. Tian H, Guan R, Salsi E, Campanini B, Bettati S, Kumar VP, Karsten WE, Mozzarelli A, Cook PF. Biochemistry; 2010 Jul 27; 49(29):6093-103. PubMed ID: 20550197 [Abstract] [Full Text] [Related]
15. Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound. Burkhard P, Tai CH, Jansonius JN, Cook PF. J Mol Biol; 2000 Oct 20; 303(2):279-86. PubMed ID: 11023792 [Abstract] [Full Text] [Related]
16. pH dependence of the absorbance and 31P NMR spectra of O-acetylserine sulfhydrylase in the absence and presence of O-acetyl-L-serine. Cook PF, Hara S, Nalabolu S, Schnackerz KD. Biochemistry; 1992 Mar 03; 31(8):2298-303. PubMed ID: 1540585 [Abstract] [Full Text] [Related]
17. [Resolution of beta-cyanoalanine synthase and recombination of its apoenzyme with pyridoxal-5'-phosphate and its analogs]. Rabinkov AG, Tolosa EA, Goriachenkova EV. Biokhimiia; 1978 Sep 03; 43(9):1674-9. PubMed ID: 719071 [Abstract] [Full Text] [Related]
18. Kinetic isotope effects as a probe of the beta-elimination reaction catalyzed by O-acetylserine sulfhydrylase. Hwang CC, Woehl EU, Minter DE, Dunn MF, Cook PF. Biochemistry; 1996 May 21; 35(20):6358-65. PubMed ID: 8639581 [Abstract] [Full Text] [Related]
19. Identification and spectral characterization of the external aldimine of the O-acetylserine sulfhydrylase reaction. Schnackerz KD, Tai CH, Simmons JW, Jacobson TM, Rao GS, Cook PF. Biochemistry; 1995 Sep 26; 34(38):12152-60. PubMed ID: 7547955 [Abstract] [Full Text] [Related]
20. Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction. Daum S, Tai CH, Cook PF. Biochemistry; 2003 Jan 14; 42(1):106-13. PubMed ID: 12515544 [Abstract] [Full Text] [Related] Page: [Next] [New Search]