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Journal Abstract Search


138 related items for PubMed ID: 7508268

  • 1. (6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin.
    Willner D, Trail PA, Hofstead SJ, King HD, Lasch SJ, Braslawsky GR, Greenfield RS, Kaneko T, Firestone RA.
    Bioconjug Chem; 1993; 4(6):521-7. PubMed ID: 7508268
    [Abstract] [Full Text] [Related]

  • 2. New hydrazone derivatives of adriamycin and their immunoconjugates--a correlation between acid stability and cytotoxicity.
    Kaneko T, Willner D, Monkovíc I, Knipe JO, Braslawsky GR, Greenfield RS, Vyas DM.
    Bioconjug Chem; 1991; 2(3):133-41. PubMed ID: 1932212
    [Abstract] [Full Text] [Related]

  • 3. Monoclonal antibody conjugates of doxorubicin prepared with branched linkers: A novel method for increasing the potency of doxorubicin immunoconjugates.
    King HD, Yurgaitis D, Willner D, Firestone RA, Yang MB, Lasch SJ, Hellström KE, Trail PA.
    Bioconjug Chem; 1999; 10(2):279-88. PubMed ID: 10077478
    [Abstract] [Full Text] [Related]

  • 4. Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone linker.
    Greenfield RS, Kaneko T, Daues A, Edson MA, Fitzgerald KA, Olech LJ, Grattan JA, Spitalny GL, Braslawsky GR.
    Cancer Res; 1990 Oct 15; 50(20):6600-7. PubMed ID: 2208122
    [Abstract] [Full Text] [Related]

  • 5. Preparation and functional evaluation of new doxorubicin immunoconjugates containing an acid-sensitive linker on small-cell lung cancer cells.
    Froesch BA, Stahel RA, Zangemeister-Wittke U.
    Cancer Immunol Immunother; 1996 Jan 15; 42(1):55-63. PubMed ID: 8625367
    [Abstract] [Full Text] [Related]

  • 6. Structural features of the antibody-A chain linkage that influence the activity and stability of ricin A chain immunotoxins.
    Cumber AJ, Westwood JH, Henry RV, Parnell GD, Coles BF, Wawrzynczak EJ.
    Bioconjug Chem; 1992 Jan 15; 3(5):397-401. PubMed ID: 1329989
    [Abstract] [Full Text] [Related]

  • 7. Monoclonal antibody 44-3A6 doxorubicin immunoconjugates: comparative in vitro anti-tumor efficacy of different conjugation methods.
    Sinkule JA, Rosen ST, Radosevich JA.
    Tumour Biol; 1991 Jan 15; 12(4):198-206. PubMed ID: 1651554
    [Abstract] [Full Text] [Related]

  • 8. Antigen-specific activity of carcinoma-reactive BR64-doxorubicin conjugates evaluated in vitro and in human tumor xenograft models.
    Trail PA, Willner D, Lasch SJ, Henderson AJ, Greenfield RS, King D, Zoeckler ME, Braslawsky GR.
    Cancer Res; 1992 Oct 15; 52(20):5693-700. PubMed ID: 1382845
    [Abstract] [Full Text] [Related]

  • 9. Doxorubicin immunoconjugates containing bivalent, lysosomally-cleavable dipeptide linkages.
    Dubowchik GM, Radia S, Mastalerz H, Walker MA, Firestone RA, Dalton King H, Hofstead SJ, Willner D, Lasch SJ, Trail PA.
    Bioorg Med Chem Lett; 2002 Jun 03; 12(11):1529-32. PubMed ID: 12031335
    [Abstract] [Full Text] [Related]

  • 10. Novel doxorubicin-monoclonal anti-carcinoembryonic antigen antibody immunoconjugate activity in vitro.
    Lau A, Bérubé G, Ford CH, Gallant M.
    Bioorg Med Chem; 1995 Oct 03; 3(10):1305-12. PubMed ID: 8564396
    [Abstract] [Full Text] [Related]

  • 11. Stabilization of chimeric BR96-doxorubicin immunoconjugate.
    Barbour NP, Paborji M, Alexander TC, Coppola WP, Bogardus JB.
    Pharm Res; 1995 Feb 03; 12(2):215-22. PubMed ID: 7784336
    [Abstract] [Full Text] [Related]

  • 12. Characterisation of the conjugate of the (6-maleimidocaproyl)hydrazone derivative of doxorubicin with lactosaminated human albumin by 13C NMR spectroscopy.
    Boga C, Fiume L, Baglioni M, Bertucci C, Farina C, Kratz F, Manerba M, Naldi M, Di Stefano G.
    Eur J Pharm Sci; 2009 Oct 08; 38(3):262-9. PubMed ID: 19695327
    [Abstract] [Full Text] [Related]

  • 13. Conjugation of doxorubicin to monoclonal anti-carcinoembryonic antigen antibody via novel thiol-directed cross-linking reagents.
    Lau A, Bérubé G, Ford CH.
    Bioorg Med Chem; 1995 Oct 08; 3(10):1299-304. PubMed ID: 8564395
    [Abstract] [Full Text] [Related]

  • 14. Comparison of hydrazone heterobifunctional cross-linking agents for reversible conjugation of thiol-containing chemistry.
    Christie RJ, Anderson DJ, Grainger DW.
    Bioconjug Chem; 2010 Oct 20; 21(10):1779-87. PubMed ID: 20695431
    [Abstract] [Full Text] [Related]

  • 15. Preparation and characterization of conjugates of monoclonal antibodies and staphylococcal enterotoxin A using a new hydrophilic cross-linker.
    Akerblom E, Dohlsten M, Brynö C, Mastej M, Steringer I, Hedlund G, Lando P, Kalland T.
    Bioconjug Chem; 1993 Oct 20; 4(6):455-66. PubMed ID: 8305515
    [Abstract] [Full Text] [Related]

  • 16. Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives. Improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared to that of the parent compound.
    Kratz F, Warnecke A, Scheuermann K, Stockmar C, Schwab J, Lazar P, Drückes P, Esser N, Drevs J, Rognan D, Bissantz C, Hinderling C, Folkers G, Fichtner I, Unger C.
    J Med Chem; 2002 Dec 05; 45(25):5523-33. PubMed ID: 12459020
    [Abstract] [Full Text] [Related]

  • 17. Effect of linker variation on the stability, potency, and efficacy of carcinoma-reactive BR64-doxorubicin immunoconjugates.
    Trail PA, Willner D, Knipe J, Henderson AJ, Lasch SJ, Zoeckler ME, TrailSmith MD, Doyle TW, King HD, Casazza AM, Braslawsky GR, Brown J, Hofstead SJ, Greenfield RS, Firestone RA, Mosure K, Kadow KF, Yang MB, Hellström KE, Hellström I.
    Cancer Res; 1997 Jan 01; 57(1):100-5. PubMed ID: 8988048
    [Abstract] [Full Text] [Related]

  • 18. Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity.
    Braslawsky GR, Kadow K, Knipe J, McGoff K, Edson M, Kaneko T, Greenfield RS.
    Cancer Immunol Immunother; 1991 Jan 01; 33(6):367-74. PubMed ID: 1878890
    [Abstract] [Full Text] [Related]

  • 19. Poly(ethylene glycol)-doxorubicin conjugates containing beta-lactamase-sensitive linkers.
    Senter PD, Svensson HP, Schreiber GJ, Rodriguez JL, Vrudhula VM.
    Bioconjug Chem; 1995 Jan 01; 6(4):389-94. PubMed ID: 7578358
    [Abstract] [Full Text] [Related]

  • 20. A novel heterobifunctional linker for formyl to thiol coupling.
    Heindel ND, Zhao HR, Egolf RA, Chang CH, Schray KJ, Emrich JG, McLaughlin JP, Woo DV.
    Bioconjug Chem; 1991 Jan 01; 2(6):427-30. PubMed ID: 1725255
    [Abstract] [Full Text] [Related]


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