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Journal Abstract Search

621 related items for PubMed ID: 7510480

  • 1. Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes.
    Shiraga T, Matsuda H, Nagase K, Iwasaki K, Noda K, Yamazaki H, Shimada T, Funae Y.
    Biochem Pharmacol; 1994 Feb 11; 47(4):727-35. PubMed ID: 7510480
    [Abstract] [Full Text] [Related]

  • 2. In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism.
    Vincent SH, Karanam BV, Painter SK, Chiu SH.
    Arch Biochem Biophys; 1992 May 01; 294(2):454-60. PubMed ID: 1373595
    [Abstract] [Full Text] [Related]

  • 3. Reconstitution of testosterone oxidation by purified rat cytochrome P450p (IIIA1).
    Halvorson M, Greenway D, Eberhart D, Fitzgerald K, Parkinson A.
    Arch Biochem Biophys; 1990 Feb 15; 277(1):166-80. PubMed ID: 2106291
    [Abstract] [Full Text] [Related]

  • 4. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
    Yamazaki H, Nakano M, Imai Y, Ueng YF, Guengerich FP, Shimada T.
    Arch Biochem Biophys; 1996 Jan 15; 325(2):174-82. PubMed ID: 8561495
    [Abstract] [Full Text] [Related]

  • 5. Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.
    Sattler M, Guengerich FP, Yun CH, Christians U, Sewing KF.
    Drug Metab Dispos; 1992 Jan 15; 20(5):753-61. PubMed ID: 1385058
    [Abstract] [Full Text] [Related]

  • 6. Cytochrome P450 isozymes catalyzing the hepatic microsomal oxidation of 9-anthraldehyde to 9-anthracene carboxylic acid in adult male rats.
    Matsunaga T, Iwawaki Y, Watanabe K, Narimatsu S, Yamamoto I, Imaoka S, Funae Y, Yoshimura H.
    Biol Pharm Bull; 1993 Sep 15; 16(9):866-9. PubMed ID: 8268852
    [Abstract] [Full Text] [Related]

  • 7. Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation.
    Pearce R, Greenway D, Parkinson A.
    Arch Biochem Biophys; 1992 Oct 15; 298(1):211-25. PubMed ID: 1381906
    [Abstract] [Full Text] [Related]

  • 8. Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes.
    Berthou F, Dreano Y, Belloc C, Kangas L, Gautier JC, Beaune P.
    Biochem Pharmacol; 1994 May 18; 47(10):1883-95. PubMed ID: 8204106
    [Abstract] [Full Text] [Related]

  • 9. Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes.
    Iribarne C, Berthou F, Baird S, Dréano Y, Picart D, Bail JP, Beaune P, Ménez JF.
    Chem Res Toxicol; 1996 Mar 18; 9(2):365-73. PubMed ID: 8839037
    [Abstract] [Full Text] [Related]

  • 10. Identification of cytochrome P450 3A1/2 as the major P450 isoform responsible for the metabolism of fentanyl by rat liver microsomes.
    Feierman DE.
    Anesth Analg; 1996 May 18; 82(5):936-41. PubMed ID: 8610902
    [Abstract] [Full Text] [Related]

  • 11. Identification of the cytochrome P450 isoenzymes involved in the metabolism of diazinon in the rat liver.
    Fabrizi L, Gemma S, Testai E, Vittozzi L.
    J Biochem Mol Toxicol; 1999 May 18; 13(1):53-61. PubMed ID: 9890448
    [Abstract] [Full Text] [Related]

  • 12. Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine; identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns.
    Chung WG, Roh HK, Kim HM, Cha YN.
    Chem Biol Interact; 1998 May 01; 113(1):1-14. PubMed ID: 9630843
    [Abstract] [Full Text] [Related]

  • 13. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H, Shimada T.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):161-9. PubMed ID: 9328296
    [Abstract] [Full Text] [Related]

  • 14. Constitutive testosterone 6 beta-hydroxylase in rat liver.
    Imaoka S, Terano Y, Funae Y.
    J Biochem; 1988 Sep 01; 104(3):481-7. PubMed ID: 3240989
    [Abstract] [Full Text] [Related]

  • 15. Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.
    Duescher RJ, Elfarra AA.
    Arch Biochem Biophys; 1994 Jun 01; 311(2):342-9. PubMed ID: 8203896
    [Abstract] [Full Text] [Related]

  • 16. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G, Longo V, Mazzaccaro A, Gervasi PG.
    Chem Res Toxicol; 1996 Jun 01; 9(5):882-90. PubMed ID: 8828925
    [Abstract] [Full Text] [Related]

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  • 19. Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
    Bullock P, Pearce R, Draper A, Podval J, Bracken W, Veltman J, Thomas P, Parkinson A.
    Drug Metab Dispos; 1995 Jul 01; 23(7):736-48. PubMed ID: 7587963
    [Abstract] [Full Text] [Related]

  • 20. Effects of bioflavonoids on hepatic P450 activities.
    Obermeier MT, White RE, Yang CS.
    Xenobiotica; 1995 Jun 01; 25(6):575-84. PubMed ID: 7483658
    [Abstract] [Full Text] [Related]

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