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613 related items for PubMed ID: 7514190

  • 1. Cytokines suppress human islet function irrespective of their effects on nitric oxide generation.
    Eizirik DL, Sandler S, Welsh N, Cetkovic-Cvrlje M, Nieman A, Geller DA, Pipeleers DG, Bendtzen K, Hellerström C.
    J Clin Invest; 1994 May; 93(5):1968-74. PubMed ID: 7514190
    [Abstract] [Full Text] [Related]

  • 2. The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.
    Pavlovic D, Chen MC, Gysemans CA, Mathieu C, Eizirik DL.
    Eur Cytokine Netw; 1999 Sep; 10(3):403-12. PubMed ID: 10477397
    [Abstract] [Full Text] [Related]

  • 3. IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans.
    Campbell IL, Iscaro A, Harrison LC.
    J Immunol; 1988 Oct 01; 141(7):2325-9. PubMed ID: 3139756
    [Abstract] [Full Text] [Related]

  • 4. S-methyl-L-thiocitrulline counteracts interleukin 1 beta induced suppression of pancreatic islet function in vitro, but does not protect against multiple low-dose streptozotocin-induced diabetes in vivo.
    Sternesjö J, Welsh N, Sandler S.
    Cytokine; 1997 May 01; 9(5):352-9. PubMed ID: 9195135
    [Abstract] [Full Text] [Related]

  • 5. Suppression of bank vole pancreatic islet function by proinflammatory cytokines.
    Blixt M, Niklasson B, Sandler S.
    Mol Cell Endocrinol; 2009 Jun 16; 305(1-2):1-5. PubMed ID: 19433255
    [Abstract] [Full Text] [Related]

  • 6. Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells.
    Darville MI, Eizirik DL.
    Diabetologia; 1998 Sep 16; 41(9):1101-8. PubMed ID: 9754830
    [Abstract] [Full Text] [Related]

  • 7. STAT5 activation by human GH protects insulin-producing cells against interleukin-1beta, interferon-gamma and tumour necrosis factor-alpha-induced apoptosis independent of nitric oxide production.
    Jensen J, Galsgaard ED, Karlsen AE, Lee YC, Nielsen JH.
    J Endocrinol; 2005 Oct 16; 187(1):25-36. PubMed ID: 16214938
    [Abstract] [Full Text] [Related]

  • 8. Nitric oxide and nitric oxide synthase mRNA induction in mouse islet cells by interferon-gamma plus tumor necrosis factor-alpha.
    Yamada K, Otabe S, Inada C, Takane N, Nonaka K.
    Biochem Biophys Res Commun; 1993 Nov 30; 197(1):22-7. PubMed ID: 7504484
    [Abstract] [Full Text] [Related]

  • 9. Induction of a macrophage-like nitric oxide synthase in cultured rat aortic endothelial cells. IL-1 beta-mediated induction regulated by tumor necrosis factor-alpha and IFN-gamma.
    Suschek C, Rothe H, Fehsel K, Enczmann J, Kolb-Bachofen V.
    J Immunol; 1993 Sep 15; 151(6):3283-91. PubMed ID: 7690801
    [Abstract] [Full Text] [Related]

  • 10. Upregulation of mitochondrial peripheral benzodiazepine receptor expression by cytokine-induced damage of human pancreatic islets.
    Trincavelli ML, Marselli L, Falleni A, Gremigni V, Ragge E, Dotta F, Santangelo C, Marchetti P, Lucacchini A, Martini C.
    J Cell Biochem; 2002 Sep 15; 84(3):636-44. PubMed ID: 11813268
    [Abstract] [Full Text] [Related]

  • 11. TNF-alpha and IFN-gamma potentiate the deleterious effects of IL-1 beta on mouse pancreatic islets mainly via generation of nitric oxide.
    Cetkovic-Cvrlje M, Eizirik DL.
    Cytokine; 1994 Jul 15; 6(4):399-406. PubMed ID: 7948748
    [Abstract] [Full Text] [Related]

  • 12. Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans.
    Corbett JA, Sweetland MA, Wang JL, Lancaster JR, McDaniel ML.
    Proc Natl Acad Sci U S A; 1993 Mar 01; 90(5):1731-5. PubMed ID: 8383325
    [Abstract] [Full Text] [Related]

  • 13. IL-1 produced and released endogenously within human islets inhibits beta cell function.
    Arnush M, Heitmeier MR, Scarim AL, Marino MH, Manning PT, Corbett JA.
    J Clin Invest; 1998 Aug 01; 102(3):516-26. PubMed ID: 9691088
    [Abstract] [Full Text] [Related]

  • 14. Cytokine-induced inhibition of insulin release from mouse pancreatic beta-cells deficient in inducible nitric oxide synthase.
    Andersson AK, Flodström M, Sandler S.
    Biochem Biophys Res Commun; 2001 Feb 23; 281(2):396-403. PubMed ID: 11181061
    [Abstract] [Full Text] [Related]

  • 15. Evidence for IL-6 production by and effects on the pancreatic beta-cell.
    Campbell IL, Cutri A, Wilson A, Harrison LC.
    J Immunol; 1989 Aug 15; 143(4):1188-91. PubMed ID: 2501390
    [Abstract] [Full Text] [Related]

  • 16. Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
    Hong TP, Andersen NA, Nielsen K, Karlsen AE, Fantuzzi G, Eizirik DL, Dinarello CA, Mandrup-Poulsen T.
    Eur Cytokine Netw; 2000 Jun 15; 11(2):193-205. PubMed ID: 10903798
    [Abstract] [Full Text] [Related]

  • 17. Initial cytokine exposure determines function of macrophages and renders them unresponsive to other cytokines.
    Erwig LP, Kluth DC, Walsh GM, Rees AJ.
    J Immunol; 1998 Aug 15; 161(4):1983-8. PubMed ID: 9712070
    [Abstract] [Full Text] [Related]

  • 18. Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production.
    Rabinovitch A, Suarez-Pinzon WL, Strynadka K, Lakey JR, Rajotte RV.
    J Clin Endocrinol Metab; 1996 Sep 15; 81(9):3197-202. PubMed ID: 8784069
    [Abstract] [Full Text] [Related]

  • 19. Human retinal pigmented epithelial cells produce nitric oxide in response to cytokines.
    Goureau O, Hicks D, Courtois Y.
    Biochem Biophys Res Commun; 1994 Jan 14; 198(1):120-6. PubMed ID: 7507317
    [Abstract] [Full Text] [Related]

  • 20. Interferon-gamma-induced interferon regulatory factor-1 (IRF-1) expression in rodent and human islet cells precedes nitric oxide production.
    Flodström M, Eizirik DL.
    Endocrinology; 1997 Jul 14; 138(7):2747-53. PubMed ID: 9202213
    [Abstract] [Full Text] [Related]

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