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198 related items for PubMed ID: 7514728

  • 1. Alkyltransferase transgenic mice: probes of chemical carcinogenesis.
    Gerson SL, Zaidi NH, Dumenco LL, Allay E, Fan CY, Liu L, O'Connor PJ.
    Mutat Res; 1994 Jun 01; 307(2):541-55. PubMed ID: 7514728
    [Abstract] [Full Text] [Related]

  • 2. Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas.
    Liu L, Allay E, Dumenco LL, Gerson SL.
    Cancer Res; 1994 Sep 01; 54(17):4648-52. PubMed ID: 8062258
    [Abstract] [Full Text] [Related]

  • 3. High level, regulated expression of the chimeric P-enolpyruvate carboxykinase (GTP)-bacterial O6-alkylguanine-DNA alkyltransferase (ada) gene in transgenic mice.
    Lim IK, Dumenco LL, Yun J, Donovan C, Warman B, Gorodetzkaya N, Wagner TE, Clapp DW, Hanson RW, Gerson SL.
    Cancer Res; 1990 Mar 15; 50(6):1701-8. PubMed ID: 2407342
    [Abstract] [Full Text] [Related]

  • 4. Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.
    Allay E, Veigl M, Gerson SL.
    Oncogene; 1999 Jun 24; 18(25):3783-7. PubMed ID: 10391687
    [Abstract] [Full Text] [Related]

  • 5. Enhanced repair of O6-methylguanine DNA adducts in the liver of transgenic mice expressing the ada gene.
    Dumenco LL, Arce C, Norton K, Yun J, Wagner T, Gerson SL.
    Cancer Res; 1991 Jul 01; 51(13):3391-8. PubMed ID: 2054779
    [Abstract] [Full Text] [Related]

  • 6. The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase.
    Dumenco LL, Allay E, Norton K, Gerson SL.
    Science; 1993 Jan 08; 259(5092):219-22. PubMed ID: 8421782
    [Abstract] [Full Text] [Related]

  • 7. Potentiation of lymphomagenesis by methylnitrosourea in mice transgenic for LMO1 is blocked by O6-alkylguanine DNA-alkyltransferase.
    Allay E, Reese JS, McGuire EA, Koç ON, Sedransk N, Gerson SL.
    Oncogene; 1997 Oct 23; 15(17):2127-32. PubMed ID: 9366529
    [Abstract] [Full Text] [Related]

  • 8. Transgenic mice expressing the bacterial O6 alkylguanine-DNA alkyltransferase gene: an animal model to study the role of DNA repair in the carcinogenesis of N-nitroso compounds.
    Dumenco LL, Donovan C, Warman B, Clapp DW, Lim IK, Yun J, Wagner T, Hanson RW, Gerson SL.
    Prog Clin Biol Res; 1990 Oct 23; 340A():369-78. PubMed ID: 2388920
    [No Abstract] [Full Text] [Related]

  • 9. Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis.
    Qin X, Zhou H, Liu L, Gerson SL.
    Carcinogenesis; 1999 Sep 23; 20(9):1667-73. PubMed ID: 10469609
    [Abstract] [Full Text] [Related]

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  • 12. Regeneration of O6-alkylguanine-DNA alkyltransferase in human lymphocytes after nitrosourea exposure.
    Gerson SL.
    Cancer Res; 1988 Sep 15; 48(18):5368-73. PubMed ID: 3409258
    [Abstract] [Full Text] [Related]

  • 13. Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.
    Qin X, Liu L, Gerson SL.
    Oncogene; 1999 Jul 29; 18(30):4394-400. PubMed ID: 10439048
    [Abstract] [Full Text] [Related]

  • 14. The immature thymocyte is protected from N-methylnitrosourea-induced lymphoma by the human MGMT-CD2 transgene.
    Zaidi NH, Allay E, Ayi TC, Li BF, Dumenco LL, Sy MS, Gerson SL.
    Carcinogenesis; 1995 May 29; 16(5):1047-53. PubMed ID: 7767963
    [Abstract] [Full Text] [Related]

  • 15. Role of DNA repair in carcinogen-induced ras mutation.
    Engelbergs J, Thomale J, Rajewsky MF.
    Mutat Res; 2000 May 30; 450(1-2):139-53. PubMed ID: 10838139
    [Abstract] [Full Text] [Related]

  • 16. Effects of inhibition of O6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea.
    Lijinsky W, Pegg AE, Anver MR, Moschel RC.
    Jpn J Cancer Res; 1994 Mar 30; 85(3):226-30. PubMed ID: 8188519
    [Abstract] [Full Text] [Related]

  • 17. Targeted expression of human O(6)-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis.
    Becker K, Dosch J, Gregel CM, Martin BA, Kaina B.
    Cancer Res; 1996 Jul 15; 56(14):3244-9. PubMed ID: 8764116
    [Abstract] [Full Text] [Related]

  • 18. Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine.
    Dolan ME, Pegg AE, Dumenco LL, Moschel RC, Gerson SL.
    Carcinogenesis; 1991 Dec 15; 12(12):2305-9. PubMed ID: 1747932
    [Abstract] [Full Text] [Related]

  • 19. Formation and persistence of DNA adducts in pouch skin fibroblasts and liver tissue of rats exposed in vivo to the monofunctional alkylating agents N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.
    Jansen JG, de Groot AJ, van Teijlingen CM, Lohman PH, Mohn GR, Vrieling H, van Zeeland AA.
    Mutat Res; 1994 May 01; 307(1):95-105. PubMed ID: 7513828
    [Abstract] [Full Text] [Related]

  • 20. Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes.
    Grombacher T, Mitra S, Kaina B.
    Carcinogenesis; 1996 Nov 01; 17(11):2329-36. PubMed ID: 8968045
    [Abstract] [Full Text] [Related]

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