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177 related items for PubMed ID: 7516655

  • 1. Agonist regulation of cellular Gs alpha-subunit levels in neuroblastoma x glioma hybrid NG108-15 cells transfected to express different levels of the human beta 2 adrenoceptor.
    Adie EJ, Milligan G.
    Biochem J; 1994 Jun 15; 300 ( Pt 3)(Pt 3):709-15. PubMed ID: 7516655
    [Abstract] [Full Text] [Related]

  • 2. Detection and analysis of agonist-induced formation of the complex of the stimulatory guanine nucleotide-binding protein with adenylate cyclase in intact wild-type and beta 2-adrenoceptor-expressing NG108-15 cells.
    Kim GD, Carr IC, Milligan G.
    Biochem J; 1995 May 15; 308 ( Pt 1)(Pt 1):275-81. PubMed ID: 7538756
    [Abstract] [Full Text] [Related]

  • 3. Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional implications.
    Adie EJ, Mullaney I, McKenzie FR, Milligan G.
    Biochem J; 1992 Jul 15; 285 ( Pt 2)(Pt 2):529-36. PubMed ID: 1379045
    [Abstract] [Full Text] [Related]

  • 4. Regulation of cellular Gs alpha levels and basal adenylyl cyclase activity by expression of the beta 2-adrenoceptor in neuroblastoma cell lines.
    Milligan G, Kim GD, Mullaney I, Adie EJ.
    Mol Cell Biochem; 1995 Jul 15; 149-150():213-6. PubMed ID: 8569731
    [Abstract] [Full Text] [Related]

  • 5. Regulation of basal adenylate cyclase activity in neuroblastoma x glioma hybrid, NG108-15, cells transfected to express the human beta 2 adrenoceptor: evidence for empty receptor stimulation of the adenylate cyclase cascade.
    Adie EJ, Milligan G.
    Biochem J; 1994 Nov 01; 303 ( Pt 3)(Pt 3):803-8. PubMed ID: 7980449
    [Abstract] [Full Text] [Related]

  • 6. Receptor availability defines the extent of agonist-mediated G-protein down-regulation in neuroblastoma x glioma hybrid cells transfected to express the beta 2-adrenoceptor.
    Kim GD, Milligan G.
    FEBS Lett; 1994 Nov 28; 355(2):166-70. PubMed ID: 7982493
    [Abstract] [Full Text] [Related]

  • 7. Beta 3-adrenoceptor agonist-induced down-regulation of Gs alpha and functional desensitization in a Chinese hamster ovary cell line expressing a beta 3-adrenoceptor refractory to down-regulation.
    Chambers J, Park J, Cronk D, Chapman C, Kennedy FR, Wilson S, Milligan G.
    Biochem J; 1994 Nov 01; 303 ( Pt 3)(Pt 3):973-8. PubMed ID: 7980470
    [Abstract] [Full Text] [Related]

  • 8. Agonist regulation of adenylate cyclase activity in neuroblastoma x glioma hybrid NG108-15 cells transfected to co-express adenylate cyclase type II and the beta 2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylate cyclase activity.
    MacEwan DJ, Kim GD, Milligan G.
    Biochem J; 1996 Sep 15; 318 ( Pt 3)(Pt 3):1033-9. PubMed ID: 8836153
    [Abstract] [Full Text] [Related]

  • 9. Expression of the human beta 2-adrenoceptor in NCB20 cells results in agonist activation of adenylyl cyclase and agonist-mediated selective down-regulation of Gs alpha.
    Mullaney I, Shah BH, Wise A, Milligan G.
    J Neurochem; 1995 Aug 15; 65(2):545-53. PubMed ID: 7616208
    [Abstract] [Full Text] [Related]

  • 10. Quantitative stoichiometry of the proteins of the stimulatory arm of the adenylyl cyclase cascade in neuroblastoma x glioma hybrid, NG108-15 cells.
    Kim GD, Adie EJ, Milligan G.
    Eur J Biochem; 1994 Jan 15; 219(1-2):135-43. PubMed ID: 8306980
    [Abstract] [Full Text] [Related]

  • 11. Equivalent regulation of wild type and an epitope-tagged variant of Gs alpha by the IP prostanoid receptor following expression in neuroblastoma x glioma hybrid, NG108-15, cells.
    Mullaney I, Milligan G.
    FEBS Lett; 1994 Oct 24; 353(3):231-4. PubMed ID: 7525345
    [Abstract] [Full Text] [Related]

  • 12. Analysis of the role of receptor number in defining the intrinsic activity and potency of partial agonists in neuroblastoma x glioma hybrid NG108-15 cells transfected to express differing levels of the human beta 2-adrenoceptor.
    MacEwan DJ, Kim GD, Milligan G.
    Mol Pharmacol; 1995 Aug 24; 48(2):316-25. PubMed ID: 7651365
    [Abstract] [Full Text] [Related]

  • 13. Gs alpha-dependent and -independent desensitisation of prostanoid IP receptor-activated adenylyl cyclase in NG108-15 cells.
    Williams RJ, Kelly E.
    Eur J Pharmacol; 1994 Jul 15; 268(2):177-86. PubMed ID: 7525317
    [Abstract] [Full Text] [Related]

  • 14. Agonist activation of transfected human M1 muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the alpha subunit of the G-protein Gq.
    Mullaney I, Dodd MW, Buckley N, Milligan G.
    Biochem J; 1993 Jan 01; 289 ( Pt 1)(Pt 1):125-31. PubMed ID: 8424750
    [Abstract] [Full Text] [Related]

  • 15. Prostaglandin E1-mediated, cyclic AMP-independent, down-regulation of Gs alpha in neuroblastoma x glioma hybrid cells.
    McKenzie FR, Milligan G.
    J Biol Chem; 1990 Oct 05; 265(28):17084-93. PubMed ID: 2170366
    [Abstract] [Full Text] [Related]

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  • 19. Interaction of the beta 2-adrenoceptor with epitope-tagged Gs alpha in NG108-15 cells.
    Mullaney I, Milligan G.
    Biochem Soc Trans; 1995 Feb 05; 23(1):7S. PubMed ID: 7538951
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