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Journal Abstract Search


495 related items for PubMed ID: 7518514

  • 1. (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization.
    Arneric SP, Sullivan JP, Briggs CA, Donnelly-Roberts D, Anderson DJ, Raszkiewicz JL, Hughes ML, Cadman ED, Adams P, Garvey DS.
    J Pharmacol Exp Ther; 1994 Jul; 270(1):310-8. PubMed ID: 7518514
    [Abstract] [Full Text] [Related]

  • 2. (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization.
    Decker MW, Brioni JD, Sullivan JP, Buckley MJ, Radek RJ, Raszkiewicz JL, Kang CH, Kim DJ, Giardina WJ, Wasicak JT.
    J Pharmacol Exp Ther; 1994 Jul; 270(1):319-28. PubMed ID: 7913497
    [Abstract] [Full Text] [Related]

  • 3. Characterization of [3H]ABT-418: a novel cholinergic channel ligand.
    Anderson DJ, Williams M, Pauly JR, Raszkiewicz JL, Campbell JE, Rotert G, Surber B, Thomas SB, Wasicak J, Arneric SP.
    J Pharmacol Exp Ther; 1995 Jun; 273(3):1434-41. PubMed ID: 7791118
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  • 4. ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties.
    Sullivan JP, Donnelly-Roberts D, Briggs CA, Anderson DJ, Gopalakrishnan M, Xue IC, Piattoni-Kaplan M, Molinari E, Campbell JE, McKenna DG, Gunn DE, Lin NH, Ryther KB, He Y, Holladay MW, Wonnacott S, Williams M, Arneric SP.
    J Pharmacol Exp Ther; 1997 Oct; 283(1):235-46. PubMed ID: 9336329
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  • 5. Regulation of human alpha4beta2 neuronal nicotinic acetylcholine receptors by cholinergic channel ligands and second messenger pathways.
    Gopalakrishnan M, Molinari EJ, Sullivan JP.
    Mol Pharmacol; 1997 Sep; 52(3):524-34. PubMed ID: 9281615
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  • 6. Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor.
    Gopalakrishnan M, Monteggia LM, Anderson DJ, Molinari EJ, Piattoni-Kaplan M, Donnelly-Roberts D, Arneric SP, Sullivan JP.
    J Pharmacol Exp Ther; 1996 Jan; 276(1):289-97. PubMed ID: 8558445
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  • 7. Pharmacological characterization of SIB-1765F: a novel cholinergic ion channel agonist.
    Sacaan AI, Reid RT, Santori EM, Adams P, Correa LD, Mahaffy LS, Bleicher L, Cosford ND, Stauderman KA, McDonald IA, Rao TS, Lloyd GK.
    J Pharmacol Exp Ther; 1997 Jan; 280(1):373-83. PubMed ID: 8996218
    [Abstract] [Full Text] [Related]

  • 8. ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization.
    Donnelly-Roberts DL, Puttfarcken PS, Kuntzweiler TA, Briggs CA, Anderson DJ, Campbell JE, Piattoni-Kaplan M, McKenna DG, Wasicak JT, Holladay MW, Williams M, Arneric SP.
    J Pharmacol Exp Ther; 1998 May; 285(2):777-86. PubMed ID: 9580626
    [Abstract] [Full Text] [Related]

  • 9. Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.
    Lin NH, Gunn DE, Ryther KB, Garvey DS, Donnelly-Roberts DL, Decker MW, Brioni JD, Buckley MJ, Rodrigues AD, Marsh KG, Anderson DJ, Buccafusco JJ, Prendergast MA, Sullivan JP, Williams M, Arneric SP, Holladay MW.
    J Med Chem; 1997 Jan 31; 40(3):385-90. PubMed ID: 9022806
    [Abstract] [Full Text] [Related]

  • 10. Anxiolytic-like effects of the novel cholinergic channel activator ABT-418.
    Brioni JD, O'Neill AB, Kim DJ, Buckley MJ, Decker MW, Arneric SP.
    J Pharmacol Exp Ther; 1994 Oct 31; 271(1):353-61. PubMed ID: 7965735
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  • 14. Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties.
    Arneric SP, Sullivan JP, Decker MW, Brioni JD, Bannon AW, Briggs CA, Donnelly-Roberts D, Radek RJ, Marsh KC, Kyncl J.
    Alzheimer Dis Assoc Disord; 1995 Oct 31; 9 Suppl 2():50-61. PubMed ID: 8534424
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  • 16. Pharmacological characterization of neuronal acetylcholine gated ion channel receptor-mediated hippocampal norepinephrine and striatal dopamine release from rat brain slices.
    Sacaan AI, Dunlop JL, Lloyd GK.
    J Pharmacol Exp Ther; 1995 Jul 31; 274(1):224-30. PubMed ID: 7542334
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  • 17. N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors.
    Wilkins LH, Grinevich VP, Ayers JT, Crooks PA, Dwoskin LP.
    J Pharmacol Exp Ther; 2003 Jan 31; 304(1):400-10. PubMed ID: 12490617
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