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196 related items for PubMed ID: 7518678

  • 1. Interaction of tacrolimus(FK506) and its metabolites with FKBP and calcineurin.
    Tamura K, Fujimura T, Iwasaki K, Sakuma S, Fujitsu T, Nakamura K, Shimomura K, Kuno T, Tanaka C, Kobayashi M.
    Biochem Biophys Res Commun; 1994 Jul 15; 202(1):437-43. PubMed ID: 7518678
    [Abstract] [Full Text] [Related]

  • 2. The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.
    Fruman DA, Bierer BE, Benes JE, Burakoff SJ, Austen KF, Katz HR.
    J Immunol; 1995 Feb 15; 154(4):1846-51. PubMed ID: 7530743
    [Abstract] [Full Text] [Related]

  • 3. Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.
    Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW.
    Nature; 1995 Dec 07; 378(6557):641-4. PubMed ID: 8524402
    [Abstract] [Full Text] [Related]

  • 4. Dynamic NMR studies of ligand-receptor interactions: design and analysis of a rapidly exchanging complex of FKBP-12/FK506 with a 24 kDa calcineurin fragment.
    Fejzo J, Lepre CA, Peng JW, Su MS, Thomson JA, Moore JM.
    Protein Sci; 1996 Sep 07; 5(9):1917-21. PubMed ID: 8880916
    [Abstract] [Full Text] [Related]

  • 5. Detection of the FK506-FKBP-calcineurin complex by a simple binding assay.
    Asami M, Kuno T, Mukai H, Tanaka C.
    Biochem Biophys Res Commun; 1993 May 14; 192(3):1388-94. PubMed ID: 7685169
    [Abstract] [Full Text] [Related]

  • 6. FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells.
    Fruman DA, Wood MA, Gjertson CK, Katz HR, Burakoff SJ, Bierer BE.
    Eur J Immunol; 1995 Feb 14; 25(2):563-71. PubMed ID: 7533090
    [Abstract] [Full Text] [Related]

  • 7. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation.
    Clipstone NA, Crabtree GR.
    Nature; 1992 Jun 25; 357(6380):695-7. PubMed ID: 1377362
    [Abstract] [Full Text] [Related]

  • 8. Control of a novel adenylyl cyclase by calcineurin.
    Paterson JM, Smith SM, Harmar AJ, Antoni FA.
    Biochem Biophys Res Commun; 1995 Sep 25; 214(3):1000-8. PubMed ID: 7575502
    [Abstract] [Full Text] [Related]

  • 9. Biology of cyclosporin A and FK506.
    Bierer BE.
    Prog Clin Biol Res; 1994 Sep 25; 390():203-23. PubMed ID: 7536944
    [No Abstract] [Full Text] [Related]

  • 10. Overexpression and characterization of a recombinant form of rat calcineurin A.
    Haddy A, Rusnak F.
    Biochem Biophys Res Commun; 1994 May 16; 200(3):1221-9. PubMed ID: 7514397
    [Abstract] [Full Text] [Related]

  • 11. Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action.
    Bierer BE.
    Chem Immunol; 1994 May 16; 59():128-55. PubMed ID: 7524531
    [No Abstract] [Full Text] [Related]

  • 12. A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor.
    Lam E, Martin MM, Timerman AP, Sabers C, Fleischer S, Lukas T, Abraham RT, O'Keefe SJ, O'Neill EA, Wiederrecht GJ.
    J Biol Chem; 1995 Nov 03; 270(44):26511-22. PubMed ID: 7592869
    [Abstract] [Full Text] [Related]

  • 13. A role for calcineurin in degranulation of murine cytotoxic T lymphocytes.
    Dutz JP, Fruman DA, Burakoff SJ, Bierer BE.
    J Immunol; 1993 Apr 01; 150(7):2591-8. PubMed ID: 7681074
    [Abstract] [Full Text] [Related]

  • 14. Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506-calcineurin complex.
    Aldape RA, Futer O, DeCenzo MT, Jarrett BP, Murcko MA, Livingston DJ.
    J Biol Chem; 1992 Aug 15; 267(23):16029-32. PubMed ID: 1379588
    [Abstract] [Full Text] [Related]

  • 15. High brain densities of the immunophilin FKBP colocalized with calcineurin.
    Steiner JP, Dawson TM, Fotuhi M, Glatt CE, Snowman AM, Cohen N, Snyder SH.
    Nature; 1992 Aug 13; 358(6387):584-7. PubMed ID: 1380130
    [Abstract] [Full Text] [Related]

  • 16. Calcineurin mutants render T lymphocytes resistant to cyclosporin A.
    Zhu D, Cardenas ME, Heitman J.
    Mol Pharmacol; 1996 Sep 13; 50(3):506-11. PubMed ID: 8794888
    [Abstract] [Full Text] [Related]

  • 17. X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex.
    Griffith JP, Kim JL, Kim EE, Sintchak MD, Thomson JA, Fitzgibbon MJ, Fleming MA, Caron PR, Hsiao K, Navia MA.
    Cell; 1995 Aug 11; 82(3):507-22. PubMed ID: 7543369
    [Abstract] [Full Text] [Related]

  • 18. Only in the presence of immunophilins can cyclosporin and FK506 disrupt in vivo binding of calcineurin A to its autoinhibitory domain yet strengthen interaction between calcineurin A and B subunits.
    Chaudhuri B, Stephan C.
    Biochem Biophys Res Commun; 1995 Oct 13; 215(2):781-90. PubMed ID: 7488022
    [Abstract] [Full Text] [Related]

  • 19. Comparative analysis of calcineurin inhibition by complexes of immunosuppressive drugs with human FK506 binding proteins.
    Weiwad M, Edlich F, Kilka S, Erdmann F, Jarczowski F, Dorn M, Moutty MC, Fischer G.
    Biochemistry; 2006 Dec 26; 45(51):15776-84. PubMed ID: 17176100
    [Abstract] [Full Text] [Related]

  • 20. Demonstration of ternary immunophilin-calcineurin complexes with the immunosuppressants cyclosporin and macrolide FK506.
    Woerly G, Weber E, Ryffel B.
    Biochem Pharmacol; 1994 Apr 20; 47(8):1435-43. PubMed ID: 7514409
    [Abstract] [Full Text] [Related]

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