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325 related items for PubMed ID: 7525652

  • 1. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
    Synold TW, Relling MV, Boyett JM, Rivera GK, Sandlund JT, Mahmoud H, Crist WM, Pui CH, Evans WE.
    J Clin Invest; 1994 Nov; 94(5):1996-2001. PubMed ID: 7525652
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  • 2. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
    Masson E, Relling MV, Synold TW, Liu Q, Schuetz JD, Sandlund JT, Pui CH, Evans WE.
    J Clin Invest; 1996 Jan 01; 97(1):73-80. PubMed ID: 8550853
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  • 4. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
    Panetta JC, Yanishevski Y, Pui CH, Sandlund JT, Rubnitz J, Rivera GK, Ribeiro R, Evans WE, Relling MV.
    Cancer Chemother Pharmacol; 2002 Nov 01; 50(5):419-28. PubMed ID: 12439601
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  • 6. Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease.
    Göker E, Lin JT, Trippett T, Elisseyeff Y, Tong WP, Niedzwiecki D, Tan C, Steinherz P, Schweitzer BI, Bertino JR.
    Leukemia; 1993 Jul 01; 7(7):1000-4. PubMed ID: 7686600
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  • 8. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Vuchich MJ, Lauer SJ, Mahoney D, Carroll AJ, Shuster JJ, Esseltine DW, Payment C, Look AT, Akabutu J.
    Blood; 1992 Sep 01; 80(5):1316-23. PubMed ID: 1381244
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  • 9. Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation.
    Jaramillo AC, Cloos J, Lemos C, Stam RW, Kaspers GJL, Jansen G, Peters GJ.
    Leuk Res; 2019 Apr 01; 79():45-51. PubMed ID: 30849662
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  • 10. Risk of relapse in childhood acute lymphoblastic leukemia is related to RBC methotrexate and mercaptopurine metabolites during maintenance chemotherapy. Nordic Society for Pediatric Hematology and Oncology.
    Schmiegelow K, Schrøder H, Gustafsson G, Kristinsson J, Glomstein A, Salmi T, Wranne L.
    J Clin Oncol; 1995 Feb 01; 13(2):345-51. PubMed ID: 7531219
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  • 11. Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine.
    Dervieux T, Hancock M, Evans W, Pui CH, Relling MV.
    Leukemia; 2002 Feb 01; 16(2):209-12. PubMed ID: 11840287
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  • 14. A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells.
    Cheng Q, Wu B, Kager L, Panetta JC, Zheng J, Pui CH, Relling MV, Evans WE.
    Pharmacogenetics; 2004 Aug 01; 14(8):557-67. PubMed ID: 15284538
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  • 15. Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia.
    Lin JT, Tong WP, Trippett TM, Niedzwiecki D, Tao Y, Tan C, Steinherz P, Schweitzer BI, Bertino JR.
    Leuk Res; 1991 Aug 01; 15(12):1191-6. PubMed ID: 1722550
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  • 16. Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy.
    Nersting J, Nielsen SN, Grell K, Paerregaard M, Abrahamsson J, Lund B, Jonsson OG, Pruunsild K, Vaitkeviciene G, Kanerva J, Schmiegelow K, Nordic Society of Paediatric Haematology and Oncology (NOPHO).
    Cancer Chemother Pharmacol; 2019 Jan 01; 83(1):53-60. PubMed ID: 30324220
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  • 17. Extended duration of prehydration does not prevent nephrotoxicity or delayed drug elimination in high-dose methotrexate infusions: a prospectively randomized cross-over study.
    Mikkelsen TS, Mamoudou AD, Tuckuviene R, Wehner PS, Schroeder H.
    Pediatr Blood Cancer; 2014 Feb 01; 61(2):297-301. PubMed ID: 24039194
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  • 18. Comparative analysis of methotrexate polyglutamates in lymphoblast preparations from bone marrow and blood, and the contribution of residual red blood cells.
    Weigand M, Frei E, Graf N, Wiessler M.
    J Cancer Res Clin Oncol; 2000 Jul 01; 126(7):407-11. PubMed ID: 10929763
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  • 19. Time course of methotrexate polyglutamate formation and degradation in the pre-B-leukaemia cell line Nalm6 and in lymphoblasts from children with leukaemia.
    Buchholz B, Frei E, Eisenbarth J, Weigand M, Ludwig R.
    Eur J Cancer; 1996 Nov 01; 32A(12):2101-7. PubMed ID: 9014752
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  • 20. A single assessment of methotrexate levels at 42 hours permits safe administration and early discharge in children with lymphoblastic lymphoma and leukemia receiving high-dose methotrexate.
    Totadri S, Srinivasan HN, Joseph LL, Boddu D, Mathew LG, John R.
    Pediatr Hematol Oncol; 2021 Aug 01; 38(5):434-443. PubMed ID: 33764242
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