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447 related items for PubMed ID: 7530743

  • 1. The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.
    Fruman DA, Bierer BE, Benes JE, Burakoff SJ, Austen KF, Katz HR.
    J Immunol; 1995 Feb 15; 154(4):1846-51. PubMed ID: 7530743
    [Abstract] [Full Text] [Related]

  • 2. FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells.
    Fruman DA, Wood MA, Gjertson CK, Katz HR, Burakoff SJ, Bierer BE.
    Eur J Immunol; 1995 Feb 15; 25(2):563-71. PubMed ID: 7533090
    [Abstract] [Full Text] [Related]

  • 3. Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12.
    Kaye RE, Fruman DA, Bierer BE, Albers MW, Zydowsky LD, Ho SI, Jin YJ, Castells MC, Schreiber SL, Walsh CT.
    Proc Natl Acad Sci U S A; 1992 Sep 15; 89(18):8542-6. PubMed ID: 1382293
    [Abstract] [Full Text] [Related]

  • 4. Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.
    Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW.
    Nature; 1995 Dec 07; 378(6557):641-4. PubMed ID: 8524402
    [Abstract] [Full Text] [Related]

  • 5. Interaction of tacrolimus(FK506) and its metabolites with FKBP and calcineurin.
    Tamura K, Fujimura T, Iwasaki K, Sakuma S, Fujitsu T, Nakamura K, Shimomura K, Kuno T, Tanaka C, Kobayashi M.
    Biochem Biophys Res Commun; 1994 Jul 15; 202(1):437-43. PubMed ID: 7518678
    [Abstract] [Full Text] [Related]

  • 6. Immunosuppressive activity of [MeBm2t]1-, D-diaminobutyryl-8-, and D-diaminopropyl-8-cyclosporin analogues correlates with inhibition of calcineurin phosphatase activity.
    Nelson PA, Akselband Y, Kawamura A, Su M, Tung RD, Rich DH, Kishore V, Rosborough SL, DeCenzo MT, Livingston DJ.
    J Immunol; 1993 Mar 15; 150(6):2139-47. PubMed ID: 7680683
    [Abstract] [Full Text] [Related]

  • 7. Calcineurin mutants render T lymphocytes resistant to cyclosporin A.
    Zhu D, Cardenas ME, Heitman J.
    Mol Pharmacol; 1996 Sep 15; 50(3):506-11. PubMed ID: 8794888
    [Abstract] [Full Text] [Related]

  • 8. A role for calcineurin in degranulation of murine cytotoxic T lymphocytes.
    Dutz JP, Fruman DA, Burakoff SJ, Bierer BE.
    J Immunol; 1993 Apr 01; 150(7):2591-8. PubMed ID: 7681074
    [Abstract] [Full Text] [Related]

  • 9. Inhibitory role for calcineurin in stimulus-secretion coupling revealed by FK506 and cyclosporin A in pituitary corticotrope tumor cells.
    Antoni FA, Shipston MJ, Smith SM.
    Biochem Biophys Res Commun; 1993 Jul 15; 194(1):226-33. PubMed ID: 7687429
    [Abstract] [Full Text] [Related]

  • 10. Cytokine mRNA are preferentially increased relative to secretory granule protein mRNA in mouse bone marrow-derived mast cells that have undergone IgE-mediated activation and degranulation.
    Gurish MF, Ghildyal N, Arm J, Austen KF, Avraham S, Reynolds D, Stevens RL.
    J Immunol; 1991 Mar 01; 146(5):1527-33. PubMed ID: 1993842
    [Abstract] [Full Text] [Related]

  • 11. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation.
    Clipstone NA, Crabtree GR.
    Nature; 1992 Jun 25; 357(6380):695-7. PubMed ID: 1377362
    [Abstract] [Full Text] [Related]

  • 12. A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor.
    Lam E, Martin MM, Timerman AP, Sabers C, Fleischer S, Lukas T, Abraham RT, O'Keefe SJ, O'Neill EA, Wiederrecht GJ.
    J Biol Chem; 1995 Nov 03; 270(44):26511-22. PubMed ID: 7592869
    [Abstract] [Full Text] [Related]

  • 13. Decrease in IgE Fc receptor expression on mouse bone marrow-derived mast cells and inhibition of paf-acether formation and of beta-hexosaminidase release by dexamethasone.
    Benhamou M, Ninio E, Salem P, Hieblot C, Bessou G, Pitton C, Liu FT, Mencia-Huerta JM.
    J Immunol; 1986 Feb 15; 136(4):1385-92. PubMed ID: 2935578
    [Abstract] [Full Text] [Related]

  • 14. FKBP12-FK506 complex inhibits phosphatase activity of two mammalian isoforms of calcineurin irrespective of their substrates or activation mechanisms.
    Mukai H, Kuno T, Chang CD, Lane B, Luly JR, Tanaka C.
    J Biochem; 1993 Mar 15; 113(3):292-8. PubMed ID: 7683641
    [Abstract] [Full Text] [Related]

  • 15. Calcineurin activation protects T cells from glucocorticoid-induced apoptosis.
    Zhao Y, Tozawa Y, Iseki R, Mukai M, Iwata M.
    J Immunol; 1995 Jun 15; 154(12):6346-54. PubMed ID: 7539018
    [Abstract] [Full Text] [Related]

  • 16. Control of a novel adenylyl cyclase by calcineurin.
    Paterson JM, Smith SM, Harmar AJ, Antoni FA.
    Biochem Biophys Res Commun; 1995 Sep 25; 214(3):1000-8. PubMed ID: 7575502
    [Abstract] [Full Text] [Related]

  • 17. Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists.
    Hatfield SM, Mynderse JS, Roehm NW.
    J Pharmacol Exp Ther; 1992 Jun 25; 261(3):970-6. PubMed ID: 1376361
    [Abstract] [Full Text] [Related]

  • 18. Nephrotoxicity of immunosuppressants in rats: comparison of macrolides with cyclosporin.
    Ryffel B, Weber E, Mihatsch MJ.
    Exp Nephrol; 1994 Jun 25; 2(6):324-33. PubMed ID: 7532090
    [Abstract] [Full Text] [Related]

  • 19. Concentrations of cyclosporin A and FK506 that inhibit IL-2 induction in human T cells do not affect TGF-beta1 biosynthesis, whereas higher doses of cyclosporin A trigger apoptosis and release of preformed TGF-beta1.
    Minguillón J, Morancho B, Kim SJ, López-Botet M, Aramburu J.
    J Leukoc Biol; 2005 May 25; 77(5):748-58. PubMed ID: 15716327
    [Abstract] [Full Text] [Related]

  • 20. Comparative analysis of calcineurin inhibition by complexes of immunosuppressive drugs with human FK506 binding proteins.
    Weiwad M, Edlich F, Kilka S, Erdmann F, Jarczowski F, Dorn M, Moutty MC, Fischer G.
    Biochemistry; 2006 Dec 26; 45(51):15776-84. PubMed ID: 17176100
    [Abstract] [Full Text] [Related]

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