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130 related items for PubMed ID: 7535121

  • 1. Reduction of MPP(+)-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase.
    Smith TS, Swerdlow RH, Parker WD, Bennett JP.
    Neuroreport; 1994 Dec 20; 5(18):2598-600. PubMed ID: 7535121
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  • 2. Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinson's disease.
    Han J, Cheng FC, Yang Z, Dryhurst G.
    J Neurochem; 1999 Oct 20; 73(4):1683-95. PubMed ID: 10501216
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  • 4. Neuronal nitric oxide synthase inhibition reduces MPP+-evoked hydroxyl radical formation but not dopamine efflux in rat striatum.
    Rose S, Hindmarsh JG, Jenner P.
    J Neural Transm (Vienna); 1999 Oct 20; 106(5-6):477-86. PubMed ID: 10443551
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  • 7. In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia.
    Chiueh CC, Wu RM, Mohanakumar KP, Sternberger LM, Krishna G, Obata T, Murphy DL.
    Ann N Y Acad Sci; 1994 Nov 17; 738():25-36. PubMed ID: 7832434
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  • 9. Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse.
    Perry TL, Yong VW, Jones K, Wall RA, Clavier RM, Foulks JG, Wright JM.
    Neurosci Lett; 1985 Aug 05; 58(3):321-6. PubMed ID: 3876525
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  • 10. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
    Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC.
    Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685
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  • 11. Dopamine efflux by MPTP and hydroxyl radical generation.
    Obata T.
    J Neural Transm (Vienna); 2002 Sep 18; 109(9):1159-80. PubMed ID: 12203043
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  • 12. Effects of noradrenergic lesions on MPTP/MPP+ kinetics and MPTP-induced nigrostriatal dopamine depletions.
    Fornai F, Alessandrì MG, Torracca MT, Bassi L, Corsini GU.
    J Pharmacol Exp Ther; 1997 Oct 18; 283(1):100-7. PubMed ID: 9336313
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  • 13. Mitochondrial toxins in models of neurodegenerative diseases. II: Elevated zif268 transcription and independent temporal regulation of striatal D1 and D2 receptor mRNAs and D1 and D2 receptor-binding sites in C57BL/6 mice during MPTP treatment.
    Smith TS, Trimmer PA, Khan SM, Tinklepaugh DL, Bennett JP.
    Brain Res; 1997 Aug 15; 765(2):189-97. PubMed ID: 9313891
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  • 14. Protective effects of neuronal nitric oxide synthase inhibitor in mouse brain against MPTP neurotoxicity: an immunohistological study.
    Watanabe H, Muramatsu Y, Kurosaki R, Michimata M, Matsubara M, Imai Y, Araki T.
    Eur Neuropsychopharmacol; 2004 Mar 15; 14(2):93-104. PubMed ID: 15013024
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  • 15. Antioxidant mechanism and protection of nigral neurons against MPP+ toxicity by deprenyl (selegiline).
    Wu RM, Mohanakumar KP, Murphy DL, Chiueh CC.
    Ann N Y Acad Sci; 1994 Nov 17; 738():214-21. PubMed ID: 7832430
    [Abstract] [Full Text] [Related]

  • 16. MPP+-induced increases in extracellular potassium ion activity in rat striatal slices suggest that consequences of MPP+ neurotoxicity are spread beyond dopaminergic terminals.
    Hollinden GE, Sanchez-Ramos JR, Sick TJ, Rosenthal M.
    Brain Res; 1988 Dec 20; 475(2):283-90. PubMed ID: 3265070
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  • 17. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum.
    Kawasaki T, Ishihara K, Ago Y, Baba A, Matsuda T.
    J Pharmacol Exp Ther; 2007 Jul 20; 322(1):274-81. PubMed ID: 17429058
    [Abstract] [Full Text] [Related]

  • 18. 1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway.
    Bradbury AJ, Costall B, Domeney AM, Jenner P, Kelly ME, Marsden CD, Naylor RJ.
    Nature; 2007 Jul 20; 319(6048):56-7. PubMed ID: 3484542
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  • 19. Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity.
    Klivenyi P, Andreassen OA, Ferrante RJ, Lancelot E, Reif D, Beal MF.
    Neuroreport; 2000 Apr 27; 11(6):1265-8. PubMed ID: 10817604
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  • 20. Blockade of 1-methyl-4-phenylpyridinium ion (MPP+) nigral toxicity in the rat by prior decortication or MK-801 treatment: a stereological estimate of neuronal loss.
    Srivastava R, Brouillet E, Beal MF, Storey E, Hyman BT.
    Neurobiol Aging; 1993 Apr 27; 14(4):295-301. PubMed ID: 8103573
    [Abstract] [Full Text] [Related]

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