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120 related items for PubMed ID: 7536413

  • 1. A role for protein kinase C-mediated phosphorylation in eliciting glucagon desensitization in rat hepatocytes.
    Savage A, Zeng L, Houslay MD.
    Biochem J; 1995 Apr 01; 307 ( Pt 1)(Pt 1):281-5. PubMed ID: 7536413
    [Abstract] [Full Text] [Related]

  • 2. Insulin and vasopressin elicit inhibition of cholera-toxin-stimulated adenylate cyclase activity in both hepatocytes and the P9 immortalized hepatocyte cell line through an action involving protein kinase C.
    Zeng L, Houslay MD.
    Biochem J; 1995 Dec 15; 312 ( Pt 3)(Pt 3):769-74. PubMed ID: 8554518
    [Abstract] [Full Text] [Related]

  • 3. The rapid desensitization of glucagon-stimulated adenylate cyclase is a cyclic AMP-independent process that can be mimicked by hormones which stimulate inositol phospholipid metabolism.
    Murphy GJ, Hruby VJ, Trivedi D, Wakelam MJ, Houslay MD.
    Biochem J; 1987 Apr 01; 243(1):39-46. PubMed ID: 3038085
    [Abstract] [Full Text] [Related]

  • 4. Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells.
    Chambers TC, Zheng B, Kuo JF.
    Mol Pharmacol; 1992 Jun 01; 41(6):1008-15. PubMed ID: 1377325
    [Abstract] [Full Text] [Related]

  • 5. Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation.
    Premont RT, Jacobowitz O, Iyengar R.
    Endocrinology; 1992 Dec 01; 131(6):2774-84. PubMed ID: 1332848
    [Abstract] [Full Text] [Related]

  • 6. Treatment of intact hepatocytes with the calcium ionophore A23187 perturbs both the synthesis and the degradation of the second messenger cyclic AMP. Actions on adenylate cyclase and cyclic AMP phosphodiesterase activities.
    Irvine FJ, Houslay MD.
    Biochem Pharmacol; 1988 Jul 15; 37(14):2773-9. PubMed ID: 2456067
    [Abstract] [Full Text] [Related]

  • 7. The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient.
    Kachra Z, Yang CR, Posner BI.
    Endocrinology; 1994 Feb 15; 134(2):702-8. PubMed ID: 7507834
    [Abstract] [Full Text] [Related]

  • 8. Analysis of the adenylate cyclase signalling system, and alterations induced by culture with insulin, in a novel SV40-DNA-immortalized hepatocyte cell line (P9 cells).
    Livingstone C, MacDonald C, Willett B, Houslay MD.
    Biochem J; 1994 Jun 15; 300 ( Pt 3)(Pt 3):835-42. PubMed ID: 8010967
    [Abstract] [Full Text] [Related]

  • 9. Treatment of intact hepatocytes with synthetic diacyl glycerols mimics the ability of glucagon to cause the desensitization of adenylate cyclase.
    Newlands C, Houslay MD.
    FEBS Lett; 1991 Sep 09; 289(2):129-32. PubMed ID: 1915834
    [Abstract] [Full Text] [Related]

  • 10. Regulation of adenylyl cyclase type VI activity during desensitization of the A2a adenosine receptor-mediated cyclic AMP response: role for protein phosphatase 2A.
    Chern Y, Chiou JY, Lai HL, Tsai MH.
    Mol Pharmacol; 1995 Jul 09; 48(1):1-8. PubMed ID: 7623763
    [Abstract] [Full Text] [Related]

  • 11. Okadaic acid identifies a phosphorylation/dephosphorylation cycle controlling the inhibitory guanine-nucleotide-binding regulatory protein Gi2.
    Bushfield M, Lavan BE, Houslay MD.
    Biochem J; 1991 Mar 01; 274 ( Pt 2)(Pt 2):317-21. PubMed ID: 1900986
    [Abstract] [Full Text] [Related]

  • 12. Glucagon desensitization of adenylate cyclase and stimulation of inositol phospholipid metabolism does not involve the inhibitory guanine nucleotide regulatory protein Gi, which is inactivated upon challenge of hepatocytes with glucagon.
    Murphy GJ, Gawler DJ, Milligan G, Wakelam MJ, Pyne NJ, Houslay MD.
    Biochem J; 1989 Apr 01; 259(1):191-7. PubMed ID: 2497730
    [Abstract] [Full Text] [Related]

  • 13. Phosphorylation of Gi alpha 2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma hybrid (NG-108-15) cells.
    Strassheim D, Malbon CC.
    J Biol Chem; 1994 May 13; 269(19):14307-13. PubMed ID: 7514603
    [Abstract] [Full Text] [Related]

  • 14. Islet-activating protein blocks glucagon desensitization in intact hepatocytes.
    Heyworth CM, Hanski E, Houslay MD.
    Biochem J; 1984 Aug 15; 222(1):189-94. PubMed ID: 6089757
    [Abstract] [Full Text] [Related]

  • 15. Extracellular calcium modulates insulin's action on enzymes controlling cyclic AMP metabolism in intact hepatocytes.
    Irvine F, Wallace AV, Sarawak SR, Houslay MD.
    Biochem J; 1993 Jul 01; 293 ( Pt 1)(Pt 1):249-53. PubMed ID: 8392336
    [Abstract] [Full Text] [Related]

  • 16. Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes.
    Heyworth CM, Houslay MD.
    Biochem J; 1983 Jul 15; 214(1):93-8. PubMed ID: 6615475
    [Abstract] [Full Text] [Related]

  • 17. Hormonal regulation of Gi2 alpha-subunit phosphorylation in intact hepatocytes.
    Bushfield M, Murphy GJ, Lavan BE, Parker PJ, Hruby VJ, Milligan G, Houslay MD.
    Biochem J; 1990 Jun 01; 268(2):449-57. PubMed ID: 2114093
    [Abstract] [Full Text] [Related]

  • 18. Decreased glucagon responsiveness by bile acids: a role for protein kinase Calpha and glucagon receptor phosphorylation.
    Ikegami T, Krilov L, Meng J, Patel B, Chapin-Kennedy K, Bouscarel B.
    Endocrinology; 2006 Nov 01; 147(11):5294-302. PubMed ID: 16916948
    [Abstract] [Full Text] [Related]

  • 19. Conditions that result in the mobilization and influx of Ca2+ into rat hepatocytes induce the rapid loss of 3-hydroxy-3-methylglutaryl-CoA reductase activity that is not reversed by phosphatase treatment.
    Zammit VA, Caldwell AM.
    Biochem J; 1990 Jul 15; 269(2):373-9. PubMed ID: 2167066
    [Abstract] [Full Text] [Related]

  • 20. Hormone-stimulated Ca2+ transport in rabbit kidney: multiple sites of inhibition by exogenous ATP.
    van Baal J, Hoenderop JG, Groenendijk M, van Os CH, Bindels RJ, Willems PH.
    Am J Physiol; 1999 Dec 15; 277(6):F899-906. PubMed ID: 10600937
    [Abstract] [Full Text] [Related]

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