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Journal Abstract Search

344 related items for PubMed ID: 7539611

  • 1.
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  • 2. A 60-kilodalton protein in rat hepatoma cells overexpressing insulin receptor was tyrosine phosphorylated and associated with Syp, phophatidylinositol 3-kinase, and Grb2 in an insulin-dependent manner.
    Zhang-Sun G, Yang C, Viallet J, Feng G, Bergeron JJ, Posner BI.
    Endocrinology; 1996 Jul; 137(7):2649-58. PubMed ID: 8770882
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  • 4. Insulin stimulates tyrosine phosphorylation of multiple high molecular weight substrates in Fao hepatoma cells.
    Miralpeix M, Sun XJ, Backer JM, Myers MG, Araki E, White MF.
    Biochemistry; 1992 Sep 22; 31(37):9031-9. PubMed ID: 1382584
    [Abstract] [Full Text] [Related]

  • 5. IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.
    Myers MG, Backer JM, Sun XJ, Shoelson S, Hu P, Schlessinger J, Yoakim M, Schaffhausen B, White MF.
    Proc Natl Acad Sci U S A; 1992 Nov 01; 89(21):10350-4. PubMed ID: 1332046
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  • 6. Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62, and GTPase-activating protein.
    Sung CK, Sánchez-Margalet V, Goldfine ID.
    J Biol Chem; 1994 Apr 29; 269(17):12503-7. PubMed ID: 8175658
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  • 7. In vitro association of the phosphatidylinositol 3-kinase regulatory subunit (p85) with the human insulin receptor.
    Ottinger EA, Hui TY, Man Z, Barany G, Bernlohr DA.
    Int J Pept Protein Res; 1995 Nov 29; 46(5):346-53. PubMed ID: 8567177
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  • 8. Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.
    Backer JM, Myers MG, Shoelson SE, Chin DJ, Sun XJ, Miralpeix M, Hu P, Margolis B, Skolnik EY, Schlessinger J.
    EMBO J; 1992 Sep 29; 11(9):3469-79. PubMed ID: 1380456
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  • 9. Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats.
    Saad MJ, Folli F, Kahn JA, Kahn CR.
    J Clin Invest; 1993 Oct 29; 92(4):2065-72. PubMed ID: 7691892
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  • 10. Changes in tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 (IRS-1) and association of p85 of phosphatidylinositol 3-kinase with IRS-1 after feeding in rat liver in vivo.
    Ito Y, Ariga M, Takahashi S, Takenaka A, Hidaka T, Noguchi T.
    J Endocrinol; 1997 Aug 29; 154(2):267-73. PubMed ID: 9291837
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  • 11. Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit.
    Rordorf-Nikolic T, Van Horn DJ, Chen D, White MF, Backer JM.
    J Biol Chem; 1995 Feb 24; 270(8):3662-6. PubMed ID: 7876105
    [Abstract] [Full Text] [Related]

  • 12. Insulin-dependent formation of a complex containing an 85-kDa subunit of phosphatidylinositol 3-kinase and tyrosine-phosphorylated insulin receptor substrate 1.
    Yonezawa K, Ueda H, Hara K, Nishida K, Ando A, Chavanieu A, Matsuba H, Shii K, Yokono K, Fukui Y.
    J Biol Chem; 1992 Dec 25; 267(36):25958-65. PubMed ID: 1334490
    [Abstract] [Full Text] [Related]

  • 13. A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment.
    Ando A, Yonezawa K, Gout I, Nakata T, Ueda H, Hara K, Kitamura Y, Noda Y, Takenawa T, Hirokawa N.
    EMBO J; 1994 Jul 01; 13(13):3033-8. PubMed ID: 8039498
    [Abstract] [Full Text] [Related]

  • 14. Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle.
    Kelly KL, Ruderman NB.
    J Biol Chem; 1993 Feb 25; 268(6):4391-8. PubMed ID: 8382701
    [Abstract] [Full Text] [Related]

  • 15. Identification by mutation of the tyrosine residues in the insulin receptor substrate-1 affecting association with the tyrosine phosphatase 2C and phosphatidylinositol 3-kinase.
    Rocchi S, Tartare-Deckert S, Mothe I, Van Obberghen E.
    Endocrinology; 1995 Dec 25; 136(12):5291-7. PubMed ID: 7588273
    [Abstract] [Full Text] [Related]

  • 16. Reciprocal feedback regulation of insulin receptor and insulin receptor substrate tyrosine phosphorylation by phosphoinositide 3-kinase in primary adipocytes.
    Hers I, Bell CJ, Poole AW, Jiang D, Denton RM, Schaefer E, Tavaré JM.
    Biochem J; 2002 Dec 15; 368(Pt 3):875-84. PubMed ID: 12220227
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  • 17.
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  • 18. Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.
    Cengel KA, Kason RE, Freund GG.
    Biochem J; 1998 Oct 15; 335 ( Pt 2)(Pt 2):397-404. PubMed ID: 9761740
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  • 20. Impact of natural IRS-1 mutations on insulin signals: mutations of IRS-1 in the PTB domain and near SH2 protein binding sites result in impaired function at different steps of IRS-1 signaling.
    Yoshimura R, Araki E, Ura S, Todaka M, Tsuruzoe K, Furukawa N, Motoshima H, Yoshizato K, Kaneko K, Matsuda K, Kishikawa H, Shichiri M.
    Diabetes; 1997 Jun 15; 46(6):929-36. PubMed ID: 9166661
    [Abstract] [Full Text] [Related]

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