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213 related items for PubMed ID: 7541711

  • 1. Activity of a single-chain immunotoxin that selectively kills lymphoma and other B-lineage cells expressing the CD40 antigen.
    Francisco JA, Gilliland LK, Stebbins MR, Norris NA, Ledbetter JA, Siegall CB.
    Cancer Res; 1995 Jul 15; 55(14):3099-104. PubMed ID: 7541711
    [Abstract] [Full Text] [Related]

  • 2. Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin.
    Francisco JA, Kiener PA, Moran-Davis P, Ledbetter JA, Siegall CB.
    J Immunol; 1996 Aug 15; 157(4):1652-8. PubMed ID: 8759752
    [Abstract] [Full Text] [Related]

  • 3. Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys.
    Kreitman RJ, Wang QC, FitzGerald DJ, Pastan I.
    Int J Cancer; 1999 Mar 31; 81(1):148-55. PubMed ID: 10077166
    [Abstract] [Full Text] [Related]

  • 4. Recombinant immunotoxins containing the VH or VL domain of monoclonal antibody B3 fused to Pseudomonas exotoxin.
    Brinkmann U, Lee BK, Pastan I.
    J Immunol; 1993 Apr 01; 150(7):2774-82. PubMed ID: 8454854
    [Abstract] [Full Text] [Related]

  • 5. Construction, expression, and characterization of BD1-G28-5 sFv, a single-chain anti-CD40 immunotoxin containing the ribosome-inactivating protein bryodin 1.
    Francisco JA, Gawlak SL, Siegall CB.
    J Biol Chem; 1997 Sep 26; 272(39):24165-9. PubMed ID: 9305866
    [Abstract] [Full Text] [Related]

  • 6. The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.
    Kreitman RJ, Chaudhary VK, Waldmann T, Willingham MC, FitzGerald DJ, Pastan I.
    Proc Natl Acad Sci U S A; 1990 Nov 26; 87(21):8291-5. PubMed ID: 2236041
    [Abstract] [Full Text] [Related]

  • 7. BR96 sFv-PE40, a potent single-chain immunotoxin that selectively kills carcinoma cells.
    Friedman PN, McAndrew SJ, Gawlak SL, Chace D, Trail PA, Brown JP, Siegall CB.
    Cancer Res; 1993 Jan 15; 53(2):334-9. PubMed ID: 8417827
    [Abstract] [Full Text] [Related]

  • 8. Recombinant single-chain immunotoxins against T and B cell leukemias.
    Kreitman RJ, Pastan I.
    Leuk Lymphoma; 1994 Mar 15; 13(1-2):1-10. PubMed ID: 8025511
    [Abstract] [Full Text] [Related]

  • 9. Single-chain immunotoxins targeted to CD40 for the treatment of human B-lineage hematologic malignancies.
    Francisco JA, Siegall CB.
    Leuk Lymphoma; 1998 Jul 15; 30(3-4):237-45. PubMed ID: 9713956
    [Abstract] [Full Text] [Related]

  • 10. Antitumor activity of the single-chain immunotoxin BR96 sFv-PE40 against established breast and lung tumor xenografts.
    Friedman PN, Chace DF, Trail PA, Siegall CB.
    J Immunol; 1993 Apr 01; 150(7):3054-61. PubMed ID: 8454873
    [Abstract] [Full Text] [Related]

  • 11. Anti-Tac(Fab)-PE40, a recombinant double-chain immunotoxin which kills interleukin-2-receptor-bearing cells and induces complete remission in an in vivo tumor model.
    Kreitman RJ, Chang CN, Hudson DV, Queen C, Bailon P, Pastan I.
    Int J Cancer; 1994 Jun 15; 57(6):856-64. PubMed ID: 8206679
    [Abstract] [Full Text] [Related]

  • 12. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.
    Benhar I, Padlan EA, Jung SH, Lee B, Pastan I.
    Proc Natl Acad Sci U S A; 1994 Dec 06; 91(25):12051-5. PubMed ID: 7991583
    [Abstract] [Full Text] [Related]

  • 13. In vivo efficacy and toxicity of a single-chain immunotoxin targeted to CD40.
    Francisco JA, Schreiber GJ, Comereski CR, Mezza LE, Warner GL, Davidson TJ, Ledbetter JA, Siegall CB.
    Blood; 1997 Jun 15; 89(12):4493-500. PubMed ID: 9192773
    [Abstract] [Full Text] [Related]

  • 14. Targeted therapy of carcinomas using BR96 sFv-PE40, a single-chain immunotoxin that binds to the Le(y) antigen.
    Siegall CB.
    Semin Cancer Biol; 1995 Oct 15; 6(5):289-95. PubMed ID: 8562906
    [Abstract] [Full Text] [Related]

  • 15. BR96 sFv-PE40 immunotoxin: nonclinical safety assessment.
    Haggerty HG, Warner WA, Comereski CR, Peden WM, Mezza LE, Damle BD, Siegall CB, Davidson TJ.
    Toxicol Pathol; 1999 Oct 15; 27(1):87-94. PubMed ID: 10367679
    [Abstract] [Full Text] [Related]

  • 16. In vitro and in vivo characterization of BR96 sFv-PE40. A single-chain immunotoxin fusion protein that cures human breast carcinoma xenografts in athymic mice and rats.
    Siegall CB, Chace D, Mixan B, Garrigues U, Wan H, Paul L, Wolff E, Hellström I, Hellström KE.
    J Immunol; 1994 Mar 01; 152(5):2377-84. PubMed ID: 8133048
    [Abstract] [Full Text] [Related]

  • 17. Cytotoxic and antitumor activity of a recombinant immunotoxin composed of disulfide-stabilized anti-Tac Fv fragment and truncated Pseudomonas exotoxin.
    Reiter Y, Kreitman RJ, Brinkmann U, Pastan I.
    Int J Cancer; 1994 Jul 01; 58(1):142-9. PubMed ID: 8014011
    [Abstract] [Full Text] [Related]

  • 18. Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells.
    Uckun FM, Gajl-Peczalska K, Myers DE, Jaszcz W, Haissig S, Ledbetter JA.
    Blood; 1990 Dec 15; 76(12):2449-56. PubMed ID: 1702326
    [Abstract] [Full Text] [Related]

  • 19. Cytotoxicity of recombinant Fab and Fv immunotoxins on adult T-cell leukemia lymph node and blood cells in the presence of soluble interleukin-2 receptor.
    Saito T, Kreitman RJ, Hanada S, Makino T, Utsunomiya A, Sumizawa T, Arima T, Chang CN, Hudson D, Pastan I.
    Cancer Res; 1994 Feb 15; 54(4):1059-64. PubMed ID: 8313362
    [Abstract] [Full Text] [Related]

  • 20. Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).
    Batra JK, Fitzgerald DJ, Chaudhary VK, Pastan I.
    Mol Cell Biol; 1991 Apr 15; 11(4):2200-5. PubMed ID: 2005905
    [Abstract] [Full Text] [Related]

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