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120 related items for PubMed ID: 7548753

  • 1. Probing the mechanism of bioactivation of MPTP type analogs by monoamine oxidase B: structure-activity studies on substituted 4-phenoxy-, 4-phenyl-, and 4-thiophenoxy-1-cyclopropyl-1,2,3,6-tetrahydropyridines.
    Rimoldi JM, Wang YX, Nimkar SK, Kuttab SH, Anderson AH, Burch H, Castagnoli N.
    Chem Res Toxicol; 1995; 8(5):703-10. PubMed ID: 7548753
    [Abstract] [Full Text] [Related]

  • 2. Chemical model studies on the monoamine oxidase-B catalyzed oxidation of 4-substituted 1-cyclopropyl-1,2,3,6-tetrahydropyridines.
    Franot C, Mabic S, Castagnoli N.
    Bioorg Med Chem; 1998 Mar; 6(3):283-91. PubMed ID: 9568282
    [Abstract] [Full Text] [Related]

  • 3. Deuterium isotope effect studies on the MAO-B catalyzed oxidation of 4-benzyl-1-cyclopropyl-1,2,3,6-tetrahydropyridine.
    Anderson AH, Kuttab S, Castagnoli N.
    Biochemistry; 1996 Mar 12; 35(10):3335-40. PubMed ID: 8605171
    [Abstract] [Full Text] [Related]

  • 4. Mechanistic studies on the monoamine oxidase B catalyzed oxidation of 1,4-disubstituted tetrahydropyridines.
    Kuttab S, Kalgutkar A, Castagnoli N.
    Chem Res Toxicol; 1994 Mar 12; 7(6):740-4. PubMed ID: 7696527
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and monoamine oxidase B catalyzed oxidation of C-4 heteroaromatic substituted 1,2,3,6-tetrahydropyridine derivatives.
    Nimkar SK, Anderson AH, Rimoldi JM, Stanton M, Castagnoli KP, Mabic S, Wang YX, Castagnoli N.
    Chem Res Toxicol; 1996 Sep 12; 9(6):1013-22. PubMed ID: 8870990
    [Abstract] [Full Text] [Related]

  • 6. Studies on the monoamine oxidase (MAO)-catalyzed oxidation of phenyl-substituted 1-methyl-4-phenoxy-1,2,3,6-tetrahydropyridine derivatives: factors contributing to MAO-A and MAO-B selectivity.
    Wang YX, Castagnoli N.
    J Med Chem; 1995 May 26; 38(11):1904-10. PubMed ID: 7783122
    [Abstract] [Full Text] [Related]

  • 7. Interaction of flexible analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of N-methyl-4-phenylpyridinium with highly purified monoamine oxidase A and B.
    Krueger MJ, Efange SM, Michelson RH, Singer TP.
    Biochemistry; 1992 Jun 23; 31(24):5611-5. PubMed ID: 1610807
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, and biological evaluation of novel 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine analogs of MPTP.
    Zhao Z, Dalvie D, Naiman N, Castagnoli K, Castagnoli N.
    J Med Chem; 1992 Nov 13; 35(23):4473-8. PubMed ID: 1447747
    [Abstract] [Full Text] [Related]

  • 9. Molecular size and flexibility as determinants of selectivity in the oxidation of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs by monoamine oxidase A and B.
    Efange SM, Michelson RH, Tan AK, Krueger MJ, Singer TP.
    J Med Chem; 1993 Apr 30; 36(9):1278-83. PubMed ID: 8487265
    [Abstract] [Full Text] [Related]

  • 10. Oxidation of analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidases A and B and the inhibition of monoamine oxidases by the oxidation products.
    Youngster SK, McKeown KA, Jin YZ, Ramsay RR, Heikkila RE, Singer TP.
    J Neurochem; 1989 Dec 30; 53(6):1837-42. PubMed ID: 2809594
    [Abstract] [Full Text] [Related]

  • 11. Assessment of structural requirements for the monoamine oxidase-B-catalyzed oxidation of 1,4-disubstituted-1,2,3,6-tetrahydropyridine derivatives related to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Mabic S, Castagnoli N.
    J Med Chem; 1996 Sep 13; 39(19):3694-700. PubMed ID: 8809158
    [Abstract] [Full Text] [Related]

  • 12. Chemical model studies on the monoamine oxidase-B catalyzed oxidation of 4-substituted 1-methyl-1,2,3,6-tetrahydropyridines.
    Franot C, Mabic S, Castagnoli N.
    Bioorg Med Chem; 1997 Aug 13; 5(8):1519-29. PubMed ID: 9313858
    [Abstract] [Full Text] [Related]

  • 13. Studies on 1,2,3,6-tetrahydropyridine derivatives as potential monoamine oxidase inactivators.
    Hall L, Murray S, Castagnoli K, Castagnoli N.
    Chem Res Toxicol; 1992 Aug 13; 5(5):625-33. PubMed ID: 1446001
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and MAO-B substrate properties of 1-methyl-4-heteroaryl-1,2,3,6-tetrahydropyridines.
    Yu J, Castagnoli N.
    Bioorg Med Chem; 1999 Feb 13; 7(2):231-9. PubMed ID: 10218814
    [Abstract] [Full Text] [Related]

  • 15. Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.
    Pretorius A, Ogunrombi MO, Terre'blanche G, Castagnoli N, Bergh JJ, Petzer JP.
    Bioorg Med Chem; 2008 Oct 01; 16(19):8813-7. PubMed ID: 18799315
    [Abstract] [Full Text] [Related]

  • 16. Novel 4-(aryloxy)tetrahydropyridine analogs of MPTP as monoamine oxidase A and B substrates.
    Kalgutkar AS, Castagnoli K, Hall A, Castagnoli N.
    J Med Chem; 1994 Apr 01; 37(7):944-9. PubMed ID: 8151621
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of novel MPTP analogs as potential monoamine oxidase B (MAO-B) inhibitors.
    Kalgutkar AS, Castagnoli N.
    J Med Chem; 1992 Oct 30; 35(22):4165-74. PubMed ID: 1433219
    [Abstract] [Full Text] [Related]

  • 18. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine- and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells: role of monoamine oxidase A.
    Basma AN, Heikkila RE, Nicklas WJ, Giovanni A, Geller HM.
    J Neurochem; 1990 Sep 30; 55(3):870-7. PubMed ID: 2384758
    [Abstract] [Full Text] [Related]

  • 19. Mechanism-based inactivation of monoamine oxidases A and B by tetrahydropyridines and dihydropyridines.
    Krueger MJ, McKeown K, Ramsay RR, Youngster SK, Singer TP.
    Biochem J; 1990 May 15; 268(1):219-24. PubMed ID: 2344359
    [Abstract] [Full Text] [Related]

  • 20. Molecular determinants in the bioactivation of the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Efange SM, Boudreau RJ.
    J Comput Aided Mol Des; 1991 Oct 15; 5(5):405-17. PubMed ID: 1685185
    [Abstract] [Full Text] [Related]

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