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67 related items for PubMed ID: 7552988

  • 1. Resistance to taxol chemotherapy produced in mouse marrow cells by safety-modified retroviruses containing a human MDR-1 transcription unit.
    Hanania EG, Fu S, Roninson I, Zu Z, Deisseroth AB.
    Gene Ther; 1995 Jun; 2(4):279-84. PubMed ID: 7552988
    [Abstract] [Full Text] [Related]

  • 2. Chemotherapy resistance to taxol in clonogenic progenitor cells following transduction of CD34 selected marrow and peripheral blood cells with a retrovirus that contains the MDR-1 chemotherapy resistance gene.
    Hanania EG, Fu S, Zu Z, Hegewisch-Becker S, Korbling M, Hester J, Durett A, Andreeff M, Mechetner E, Holzmayer T.
    Gene Ther; 1995 Jun; 2(4):285-94. PubMed ID: 7552989
    [Abstract] [Full Text] [Related]

  • 3. Serial transplantation shows that early hematopoietic precursor cells are transduced by MDR-1 retroviral vector in a mouse gene therapy model.
    Hanania EG, Deisseroth AB.
    Cancer Gene Ther; 1994 Mar; 1(1):21-5. PubMed ID: 7621234
    [Abstract] [Full Text] [Related]

  • 4. Drug-selected co-expression of P-glycoprotein and gp91 in vivo from an MDR1-bicistronic retrovirus vector Ha-MDR-IRES-gp91.
    Sugimoto Y, Tsukahara S, Sato S, Suzuki M, Nunoi H, Malech HL, Gottesman MM, Tsuruo T.
    J Gene Med; 2003 May; 5(5):366-76. PubMed ID: 12731085
    [Abstract] [Full Text] [Related]

  • 5. Simultaneous genetic chemoprotection of normal marrow cells and genetic chemosensitization of breast cancer cells in a mouse cancer gene therapy model.
    Hanania EG, Deisseroth AB.
    Clin Cancer Res; 1997 Feb; 3(2):281-6. PubMed ID: 9815684
    [Abstract] [Full Text] [Related]

  • 6. Coexpression of a multidrug resistance gene (MDR1) and herpes simplex virus thymidine kinase gene in a bicistronic retroviral vector Ha-MDR-IRES-TK allows selective killing of MDR1-transduced human tumors transplanted in nude mice.
    Sugimoto Y, Sato S, Tsukahara S, Suzuki M, Okochi E, Gottesman MM, Pastan I, Tsuruo T.
    Cancer Gene Ther; 1997 Feb; 4(1):51-8. PubMed ID: 9012451
    [Abstract] [Full Text] [Related]

  • 7. Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients.
    Cowan KH, Moscow JA, Huang H, Zujewski JA, O'Shaughnessy J, Sorrentino B, Hines K, Carter C, Schneider E, Cusack G, Noone M, Dunbar C, Steinberg S, Wilson W, Goldspiel B, Read EJ, Leitman SF, McDonagh K, Chow C, Abati A, Chiang Y, Chang YN, Gottesman MM, Pastan I, Nienhuis A.
    Clin Cancer Res; 1999 Jul; 5(7):1619-28. PubMed ID: 10430060
    [Abstract] [Full Text] [Related]

  • 8. Retroviral coexpression of two different types of drug resistance genes to protect normal cells from combination chemotherapy.
    Suzuki M, Sugimoto Y, Tsukahara S, Okochi E, Gottesman MM, Tsuruo T.
    Clin Cancer Res; 1997 Jun; 3(6):947-54. PubMed ID: 9815770
    [Abstract] [Full Text] [Related]

  • 9. Chemoprotection effect of retroviral vector encoding multidrug resistance 1 gene to allow intensified chemotherapy in vivo.
    Guo CB, Li YC, Jin XQ.
    Cancer Chemother Pharmacol; 2006 Jul; 58(1):40-9. PubMed ID: 16284790
    [Abstract] [Full Text] [Related]

  • 10. Antileukemic effect of interleukin-2-transduced murine bone marrow after autologous transplantation.
    Tam YK, Klingemann HG.
    Biol Blood Marrow Transplant; 1999 Jul; 5(4):231-42. PubMed ID: 10465103
    [Abstract] [Full Text] [Related]

  • 11. Prolonged systemic expression of human IL-1 receptor antagonist (hIL-1ra) in mice reconstituted with hematopoietic cells transduced with a retrovirus carrying the hIL-1ra cDNA.
    Boggs SS, Patrene KD, Mueller GM, Evans CH, Doughty LA, Robbins PD.
    Gene Ther; 1995 Nov; 2(9):632-8. PubMed ID: 8548552
    [Abstract] [Full Text] [Related]

  • 12. Chemoprotection effect of multidrug resistance 1 (MDR1) gene transfer to hematopoietic progenitor cells and engrafted in mice with cancer allows intensified chemotherapy.
    Guo C, Jin X.
    Cancer Invest; 2006 Nov; 24(7):659-68. PubMed ID: 17118775
    [Abstract] [Full Text] [Related]

  • 13. Retroviral-mediated transfer of the murine interleukin-3 gene engineered for intracellular retention results in a myeloproliferative syndrome but is associated with circulating interleukin-3 levels.
    Orchard PJ, Detrick RA, Gorden K, Dunbar CE, Vallera DA, Taylor P, McIvor RS, Blazar BR.
    Exp Hematol; 1993 Aug; 21(9):1245-54. PubMed ID: 8330649
    [Abstract] [Full Text] [Related]

  • 14. Retroviral transfer and expression of the human multiple drug resistance (MDR) gene in peripheral blood progenitor cells.
    Ward M, Pioli P, Ayello J, Reiss R, Urzi G, Richardson C, Hesdorffer C, Bank A.
    Clin Cancer Res; 1996 May; 2(5):873-6. PubMed ID: 9816243
    [Abstract] [Full Text] [Related]

  • 15. Engineered stromal layers and continuous flow culture enhance multidrug resistance gene transfer in hematopoietic progenitors.
    Bertolini F, Battaglia M, Corsini C, Lazzari L, Soligo D, Zibera C, Thalmeier K.
    Cancer Res; 1996 Jun 01; 56(11):2566-72. PubMed ID: 8653699
    [Abstract] [Full Text] [Related]

  • 16. Selective expression of methotrexate-resistant dihydrofolate reductase (DHFR) activity in mice transduced with DHFR retrovirus and administered methotrexate.
    Vinh DB, McIvor RS.
    J Pharmacol Exp Ther; 1993 Nov 01; 267(2):989-96. PubMed ID: 8246174
    [Abstract] [Full Text] [Related]

  • 17. Chemotherapy immediately following autologous stem-cell transplantation in patients with advanced breast cancer.
    Rahman Z, Kavanagh J, Champlin R, Giles R, Hanania E, Fu S, Zu Z, Mehra R, Holmes F, Kudelka A, Claxton D, Verschraegen C, Gajewski J, Andreeff M, Heimfeld S, Berenson R, Ellerson D, Calvert L, Mechetner E, Holzmayer T, Dayne A, Hamer J, Bachier C, Ostrove J, Deisseroth A.
    Clin Cancer Res; 1998 Nov 01; 4(11):2717-21. PubMed ID: 9829734
    [Abstract] [Full Text] [Related]

  • 18. In vivo methotrexate selection of murine hemopoietic cells transduced with a retroviral vector for Gaucher disease.
    Havenga M, Valerio D, Hoogerbrugge P, Es H.
    Gene Ther; 1999 Oct 01; 6(10):1661-9. PubMed ID: 10516714
    [Abstract] [Full Text] [Related]

  • 19. Drug selection of MDR1-transduced hematopoietic cells ex vivo increases transgene expression and chemoresistance in reconstituted bone marrow in mice.
    Licht T, Goldenberg SK, Vieira WD, Gottesman MM, Pastan I.
    Gene Ther; 2000 Feb 01; 7(4):348-58. PubMed ID: 10694816
    [Abstract] [Full Text] [Related]

  • 20. Transfer and expression of the human multiple drug resistance gene into live mice.
    Podda S, Ward M, Himelstein A, Richardson C, de la Flor-Weiss E, Smith L, Gottesman M, Pastan I, Bank A.
    Proc Natl Acad Sci U S A; 1992 Oct 15; 89(20):9676-80. PubMed ID: 1357667
    [Abstract] [Full Text] [Related]

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