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Journal Abstract Search

261 related items for PubMed ID: 7558596

  • 1. Structure-activity relationships of dermorphin analogues containing N-substituted amino acids in the 2-position of the peptide sequence.
    Schmidt R, Kálmán A, Chung NN, Lemieux C, Horváth C, Schiller PW.
    Int J Pept Protein Res; 1995 Jul; 46(1):47-55. PubMed ID: 7558596
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
    Ananthan S, Johnson CA, Carter RL, Clayton SD, Rice KC, Xu H, Davis P, Porreca F, Rothman RB.
    J Med Chem; 1998 Jul 16; 41(15):2872-81. PubMed ID: 9667975
    [Abstract] [Full Text] [Related]

  • 3. Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
    Salvadori S, Balboni G, Guerrini R, Tomatis R, Bianchi C, Bryant SD, Cooper PS, Lazarus LH.
    J Med Chem; 1997 Sep 12; 40(19):3100-8. PubMed ID: 9301674
    [Abstract] [Full Text] [Related]

  • 4. Cyclic beta-casomorphin analogues with mixed mu agonist/delta antagonist properties: synthesis, pharmacological characterization, and conformational aspects.
    Schmidt R, Vogel D, Mrestani-Klaus C, Brandt W, Neubert K, Chung NN, Lemieux C, Schiller PW.
    J Med Chem; 1994 Apr 15; 37(8):1136-44. PubMed ID: 8164255
    [Abstract] [Full Text] [Related]

  • 5. Conformationally restricted deltorphin analogues.
    Schiller PW, Weltrowska G, Nguyen TM, Wilkes BC, Chung NN, Lemieux C.
    J Med Chem; 1992 Oct 16; 35(21):3956-61. PubMed ID: 1331451
    [Abstract] [Full Text] [Related]

  • 6. Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists.
    Schiller PW, Nguyen TM, Weltrowska G, Wilkes BC, Marsden BJ, Lemieux C, Chung NN.
    Proc Natl Acad Sci U S A; 1992 Dec 15; 89(24):11871-5. PubMed ID: 1334552
    [Abstract] [Full Text] [Related]

  • 7. Side chain methyl substitution in the delta-opioid receptor antagonist TIPP has an important effect on the activity profile.
    Tourwé D, Mannekens E, Diem TN, Verheyden P, Jaspers H, Tóth G, Péter A, Kertész I, Török G, Chung NN, Schiller PW.
    J Med Chem; 1998 Dec 17; 41(26):5167-76. PubMed ID: 9857087
    [Abstract] [Full Text] [Related]

  • 8. Conversion of delta-, kappa- and mu-receptor selective opioid peptide agonists into delta-, kappa- and mu-selective antagonists.
    Schiller PW, Weltrowska G, Nguyen TM, Lemieux C, Chung NN, Lu Y.
    Life Sci; 2003 Jun 27; 73(6):691-8. PubMed ID: 12801590
    [Abstract] [Full Text] [Related]

  • 9. Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays.
    Bonner GG, Davis P, Stropova D, Edsall S, Yamamura HI, Porreca F, Hruby VJ.
    J Med Chem; 2000 Feb 24; 43(4):569-80. PubMed ID: 10691683
    [Abstract] [Full Text] [Related]

  • 10. Delta opioidmimetic antagonists: prototypes for designing a new generation of ultraselective opioid peptides.
    Salvadori S, Attila M, Balboni G, Bianchi C, Bryant SD, Crescenzi O, Guerrini R, Picone D, Tancredi T, Temussi PA.
    Mol Med; 1995 Sep 24; 1(6):678-89. PubMed ID: 8529134
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  • 14. Conversion of enkephalin and dermorphin into delta-selective opioid antagonists by single-residue substitution.
    Tancredi T, Salvadori S, Amodeo P, Picone D, Lazarus LH, Bryant SD, Guerrini R, Marzola G, Temussi PA.
    Eur J Biochem; 1994 Aug 15; 224(1):241-7. PubMed ID: 8076645
    [Abstract] [Full Text] [Related]

  • 15. Pseudoproline-containing analogues of morphiceptin and endomorphin-2: evidence for a cis Tyr-Pro amide bond in the bioactive conformation.
    Keller M, Boissard C, Patiny L, Chung NN, Lemieux C, Mutter M, Schiller PW.
    J Med Chem; 2001 Nov 08; 44(23):3896-903. PubMed ID: 11689075
    [Abstract] [Full Text] [Related]

  • 16. Highly potent side chain-main chain cyclized dermorphin-deltorphin analogues: an integrated approach including synthesis, bioassays, NMR spectroscopy and molecular modelling.
    Ro S, Zhu Q, Lee CW, Goodman M, Darlak K, Spatola AF, Chung NN, Schiller PW, Malmberg AB, Yaksh TL.
    J Pept Sci; 1995 Nov 08; 1(3):157-74. PubMed ID: 9222993
    [Abstract] [Full Text] [Related]

  • 17. Pharmacology of [Tyr1]nociceptin analogs: receptor binding and bioassay studies.
    Varani K, Rizzi A, Calo G, Bigoni R, Toth G, Guerrini R, Gessi S, Salvadori S, Borea PA, Regoli D.
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Sep 08; 360(3):270-7. PubMed ID: 10543428
    [Abstract] [Full Text] [Related]

  • 18. Opioid peptides: synthesis and biological properties of [(N gamma-glucosyl,N gamma-methoxy)-alpha, gamma-diamino-(S)-butanoyl]4-deltorphin-1-neoglycopeptide and related analogues.
    Filira F, Biondi B, Biondi L, Giannini E, Gobbo M, Negri L, Rocchi R.
    Org Biomol Chem; 2003 Sep 07; 1(17):3059-63. PubMed ID: 14518129
    [Abstract] [Full Text] [Related]

  • 19. Dermenkephalin (Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2): a potent and fully specific agonist for the delta opioid receptor.
    Amiche M, Sagan S, Mor A, Delfour A, Nicolas P.
    Mol Pharmacol; 1989 Jun 07; 35(6):774-9. PubMed ID: 2543911
    [Abstract] [Full Text] [Related]

  • 20. Design and synthesis of 1-aminocycloalkane-1-carboxylic acid-substituted deltorphin analogues: unique delta and mu opioid activity in modified peptides.
    Breveglieri A, Guerrini R, Salvadori S, Bianchi C, Bryant SD, Attila M, Lazarus LH.
    J Med Chem; 1996 Feb 02; 39(3):773-80. PubMed ID: 8576920
    [Abstract] [Full Text] [Related]

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