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74 related items for PubMed ID: 7562521
1. Inactivation of Escherichia coli-expressed rabbit cytochrome P-450 2C enzymes by 17 beta-substituted steroids. Klekotka PA, Richardson TH, Johnson EF, Halpert JR. J Pharmacol Exp Ther; 1995 Sep; 274(3):1450-5. PubMed ID: 7562521 [Abstract] [Full Text] [Related]
2. Selective inactivation by 21-chlorinated steroids of rabbit liver and adrenal microsomal cytochromes P-450 involved in progesterone hydroxylation. Halpert J, Jaw JY, Balfour C, Mash EA, Johnson EF. Arch Biochem Biophys; 1988 Aug 01; 264(2):462-71. PubMed ID: 3261153 [Abstract] [Full Text] [Related]
3. Selective inactivation of four rat liver microsomal androstenedione hydroxylases by chloramphenicol analogs. Stevens JC, Halpert J. Mol Pharmacol; 1988 Jan 01; 33(1):103-10. PubMed ID: 3336347 [Abstract] [Full Text] [Related]
4. Specific inactivation by 17 beta-substituted steroids of rabbit and rat liver cytochromes P-450 responsible for progesterone 21-hydroxylation. Halpert J, Jaw JY, Balfour C. Mol Pharmacol; 1989 Jan 01; 35(1):148-56. PubMed ID: 2783620 [Abstract] [Full Text] [Related]
5. Purification and characterization of recombinant-expressed cytochrome P450 2C3 from Escherichia coli: 2C3 encodes the 6 beta-hydroxylase deficient form of P450 3b. Richardson TH, Hsu MH, Kronbach T, Barnes HJ, Chan G, Waterman MR, Kemper B, Johnson EF. Arch Biochem Biophys; 1993 Jan 01; 300(1):510-6. PubMed ID: 8380971 [Abstract] [Full Text] [Related]
6. Selective inactivation of rat liver cytochromes P-450 by 21-chlorinated steroids. Halpert J, Jaw JY, Cornfield LJ, Balfour C, Mash EA. Drug Metab Dispos; 1989 Jan 01; 17(1):26-31. PubMed ID: 2566465 [Abstract] [Full Text] [Related]
7. Alterations of the regiospecificity of progesterone metabolism by the mutagenesis of two key amino acid residues in rabbit cytochrome P450 2C3v. Richardson TH, Johnson EF. J Biol Chem; 1994 Sep 30; 269(39):23937-43. PubMed ID: 7929041 [Abstract] [Full Text] [Related]
9. A universal approach to the expression of human and rabbit cytochrome P450s of the 2C subfamily in Escherichia coli. Richardson TH, Jung F, Griffin KJ, Wester M, Raucy JL, Kemper B, Bornheim LM, Hassett C, Omiecinski CJ, Johnson EF. Arch Biochem Biophys; 1995 Oct 20; 323(1):87-96. PubMed ID: 7487078 [Abstract] [Full Text] [Related]
10. Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis. He YA, He YQ, Szklarz GD, Halpert JR. Biochemistry; 1997 Jul 22; 36(29):8831-9. PubMed ID: 9220969 [Abstract] [Full Text] [Related]
11. A single amino acid substitution confers progesterone 6 beta-hydroxylase activity to rabbit cytochrome P450 2C3. Hsu MH, Griffin KJ, Wang Y, Kemper B, Johnson EF. J Biol Chem; 1993 Apr 05; 268(10):6939-44. PubMed ID: 8463225 [Abstract] [Full Text] [Related]
13. Selective suppression of rat hepatic cytochrome P450 2C11 by chloramphenicol. Kraner JC, Morgan ET, Halpert JR. J Pharmacol Exp Ther; 1994 Sep 05; 270(3):1367-72. PubMed ID: 7932191 [Abstract] [Full Text] [Related]
14. Mechanism-based inactivation of bovine adrenal cytochromes P450 C-21 and P450 17 alpha by 17 beta-substituted steroids. Stevens JC, Jaw JY, Peng CT, Halpert J. Biochemistry; 1991 Apr 16; 30(15):3649-85. PubMed ID: 2015223 [Abstract] [Full Text] [Related]
15. Some enzymatic vagaries of a bovine adrenal microsomal cytochrome P-450 introduced and expressed in transformed monkey kidney cells. Estabrook RW, Mason JI, Martin-Wixtrom C, Zuber M, Waterman MR. Prog Clin Biol Res; 1988 Apr 16; 274():525-40. PubMed ID: 3406037 [Abstract] [Full Text] [Related]
16. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. Straub P, Johnson EF, Kemper B. Arch Biochem Biophys; 1993 Nov 01; 306(2):521-7. PubMed ID: 8215458 [Abstract] [Full Text] [Related]
17. Functional and structural polymorphism of rabbit microsomal cytochrome P-450 form 3b. Dieter HH, Johnson EF. J Biol Chem; 1982 Aug 25; 257(16):9315-23. PubMed ID: 7107572 [Abstract] [Full Text] [Related]