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268 related items for PubMed ID: 7565670

  • 1. A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function.
    Catling AD, Schaeffer HJ, Reuter CW, Reddy GR, Weber MJ.
    Mol Cell Biol; 1995 Oct; 15(10):5214-25. PubMed ID: 7565670
    [Abstract] [Full Text] [Related]

  • 2. Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells.
    Wu X, Noh SJ, Zhou G, Dixon JE, Guan KL.
    J Biol Chem; 1996 Feb 09; 271(6):3265-71. PubMed ID: 8621729
    [Abstract] [Full Text] [Related]

  • 3. The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells.
    Dang A, Frost JA, Cobb MH.
    J Biol Chem; 1998 Jul 31; 273(31):19909-13. PubMed ID: 9677429
    [Abstract] [Full Text] [Related]

  • 4. Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.
    Zheng CF, Guan KL.
    EMBO J; 1994 Mar 01; 13(5):1123-31. PubMed ID: 8131746
    [Abstract] [Full Text] [Related]

  • 5. Mek1 phosphorylation site mutants activate Raf-1 in NIH 3T3 cells.
    Alessandrini A, Greulich H, Huang W, Erikson RL.
    J Biol Chem; 1996 Dec 06; 271(49):31612-8. PubMed ID: 8940180
    [Abstract] [Full Text] [Related]

  • 6. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.
    Zheng CF, Guan KL.
    J Biol Chem; 1993 May 25; 268(15):11435-9. PubMed ID: 8388392
    [Abstract] [Full Text] [Related]

  • 7. Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism.
    Xu S, Khoo S, Dang A, Witt S, Do V, Zhen E, Schaefer EM, Cobb MH.
    Mol Endocrinol; 1997 Oct 25; 11(11):1618-25. PubMed ID: 9328344
    [Abstract] [Full Text] [Related]

  • 8. Properties of MEKs, the kinases that phosphorylate and activate the extracellular signal-regulated kinases.
    Zheng CF, Guan KL.
    J Biol Chem; 1993 Nov 15; 268(32):23933-9. PubMed ID: 8226933
    [Abstract] [Full Text] [Related]

  • 9. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins.
    Frost JA, Steen H, Shapiro P, Lewis T, Ahn N, Shaw PE, Cobb MH.
    EMBO J; 1997 Nov 03; 16(21):6426-38. PubMed ID: 9351825
    [Abstract] [Full Text] [Related]

  • 10. MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase.
    Xu S, Robbins D, Frost J, Dang A, Lange-Carter C, Cobb MH.
    Proc Natl Acad Sci U S A; 1995 Jul 18; 92(15):6808-12. PubMed ID: 7624324
    [Abstract] [Full Text] [Related]

  • 11. Biochemical and biological analysis of Mek1 phosphorylation site mutants.
    Huang W, Kessler DS, Erikson RL.
    Mol Biol Cell; 1995 Mar 18; 6(3):237-45. PubMed ID: 7612960
    [Abstract] [Full Text] [Related]

  • 12. B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP.
    Vaillancourt RR, Gardner AM, Johnson GL.
    Mol Cell Biol; 1994 Oct 18; 14(10):6522-30. PubMed ID: 7935374
    [Abstract] [Full Text] [Related]

  • 13. MEK1 and the extracellular signal-regulated kinases are required for the stimulation of IL-2 gene transcription in T cells.
    Whitehurst CE, Geppert TD.
    J Immunol; 1996 Feb 01; 156(3):1020-9. PubMed ID: 8557975
    [Abstract] [Full Text] [Related]

  • 14. The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras.
    Jaiswal RK, Moodie SA, Wolfman A, Landreth GE.
    Mol Cell Biol; 1994 Oct 01; 14(10):6944-53. PubMed ID: 7935411
    [Abstract] [Full Text] [Related]

  • 15. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf.
    Lange-Carter CA, Pleiman CM, Gardner AM, Blumer KJ, Johnson GL.
    Science; 1993 Apr 16; 260(5106):315-9. PubMed ID: 8385802
    [Abstract] [Full Text] [Related]

  • 16. Association of MEK1 with p21ras.GMPPNP is dependent on B-Raf.
    Moodie SA, Paris MJ, Kolch W, Wolfman A.
    Mol Cell Biol; 1994 Nov 16; 14(11):7153-62. PubMed ID: 7935430
    [Abstract] [Full Text] [Related]

  • 17. PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway.
    Coles LC, Shaw PE.
    Oncogene; 2002 Mar 28; 21(14):2236-44. PubMed ID: 11948406
    [Abstract] [Full Text] [Related]

  • 18. Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells.
    Pritchard CA, Samuels ML, Bosch E, McMahon M.
    Mol Cell Biol; 1995 Nov 28; 15(11):6430-42. PubMed ID: 7565795
    [Abstract] [Full Text] [Related]

  • 19. Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators.
    Reuter CW, Catling AD, Jelinek T, Weber MJ.
    J Biol Chem; 1995 Mar 31; 270(13):7644-55. PubMed ID: 7706312
    [Abstract] [Full Text] [Related]

  • 20. Identification and characterization of an auto-activating MEK kinase from bovine brain: phosphorylation of serine-298 in the proline-rich domain of the mammalian MEKs.
    Wang J, Vantus T, Merlevede W, Vandenheede JR.
    Int J Biochem Cell Biol; 1997 Mar 31; 29(8-9):1071-83. PubMed ID: 9416003
    [Abstract] [Full Text] [Related]

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