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Journal Abstract Search

111 related items for PubMed ID: 7572339

  • 1. Preferential kill of hypoxic EMT6 mammary tumor cells by the bioreductive alkylating agent porfiromycin.
    Sartorelli AC, Belcourt MF, Hodnick WF, Keyes SR, Pritsos CA, Rockwell S.
    Adv Enzyme Regul; 1995; 35():117-30. PubMed ID: 7572339
    [Abstract] [Full Text] [Related]

  • 2. Mitomycin C: a prototype bioreductive agent.
    Sartorelli AC, Hodnick WF, Belcourt MF, Tomasz M, Haffty B, Fischer JJ, Rockwell S.
    Oncol Res; 1994; 6(10-11):501-8. PubMed ID: 7620218
    [Abstract] [Full Text] [Related]

  • 3. Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C.
    Keyes SR, Heimbrook DC, Fracasso PM, Rockwell S, Sligar SG, Sartorelli AC.
    Adv Enzyme Regul; 1985; 23():291-307. PubMed ID: 3934922
    [Abstract] [Full Text] [Related]

  • 4. Porfiromycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1985 Aug; 45(8):3642-5. PubMed ID: 3926306
    [Abstract] [Full Text] [Related]

  • 5. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM, Sartorelli AC.
    Cancer Res; 1986 Aug; 46(8):3939-44. PubMed ID: 3089583
    [Abstract] [Full Text] [Related]

  • 6. Effects of mitomycin C and porfiromycin on exponentially growing and plateau phase cultures.
    Rockwell S, Hughes CS.
    Cell Prolif; 1994 Mar; 27(3):153-63. PubMed ID: 10465006
    [Abstract] [Full Text] [Related]

  • 7. Generation of reactive oxygen radicals through bioactivation of mitomycin antibiotics.
    Pritsos CA, Sartorelli AC.
    Cancer Res; 1986 Jul; 46(7):3528-32. PubMed ID: 3011250
    [Abstract] [Full Text] [Related]

  • 8. Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase.
    Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC.
    Adv Enzyme Regul; 1998 Jul; 38():111-33. PubMed ID: 9762350
    [Abstract] [Full Text] [Related]

  • 9. Therapeutic attack of hypoxic cells of solid tumors: presidential address.
    Sartorelli AC.
    Cancer Res; 1988 Feb 15; 48(4):775-8. PubMed ID: 3123053
    [Abstract] [Full Text] [Related]

  • 10. Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1989 Jun 15; 49(12):3310-3. PubMed ID: 2470504
    [Abstract] [Full Text] [Related]

  • 11. Studies on the mechanism of the cytotoxic action of the mitomycin antibiotics in hypoxic and oxygenated EMT6 cells.
    Sartorelli AC, Tomasz M, Rockwell S.
    Adv Enzyme Regul; 1993 Jun 15; 33():3-17. PubMed ID: 8356915
    [Abstract] [Full Text] [Related]

  • 12. Correlation between drug uptake and selective toxicity of porfiromycin to hypoxic EMT6 cells.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1987 Nov 01; 47(21):5654-7. PubMed ID: 3664473
    [Abstract] [Full Text] [Related]

  • 13. Interactions of BMS-181174 and radiation: studies with EMT6 cells in vitro and in solid tumors.
    Rockwell S, Kelley M.
    Radiother Oncol; 1996 Apr 01; 39(1):65-71. PubMed ID: 8735495
    [Abstract] [Full Text] [Related]

  • 14. Effect of the superoxide dismutase inhibitor, diethyldithiocarbamate, on the cytotoxicity of mitomycin antibiotics.
    Pritsos CA, Keyes SR, Sartorelli AC.
    Cancer Biochem Biophys; 1989 Oct 01; 10(4):289-98. PubMed ID: 2559790
    [Abstract] [Full Text] [Related]

  • 15. Addition of a hypoxic cell selective cytotoxic agent (mitomycin C or porfiromycin) to Fluosol-DA/carbogen/radiation.
    Holden SA, Herman TS, Teicher BA.
    Radiother Oncol; 1990 May 01; 18(1):59-70. PubMed ID: 2113698
    [Abstract] [Full Text] [Related]

  • 16. Cytotoxicity and DNA crosslinks produced by mitomycin analogs in aerobic and hypoxic EMT6 cells.
    Keyes SR, Loomis R, DiGiovanna MP, Pritsos CA, Rockwell S, Sartorelli AC.
    Cancer Commun; 1991 May 01; 3(10-11):351-6. PubMed ID: 1760250
    [Abstract] [Full Text] [Related]

  • 17. Activity of C-7 substituted cyclic acetal derivatives of mitomycin C and porfiromycin against hypoxic and oxygenated EMT6 carcinoma cells in vitro and in vivo.
    Rockwell S, Keyes SR, Loomis R, Kelley M, Vyas DM, Wong H, Doyle TW, Sartorelli AC.
    Cancer Commun; 1991 Jun 01; 3(6):191-8. PubMed ID: 2049227
    [Abstract] [Full Text] [Related]

  • 18. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
    Keyes SR, Fracasso PM, Heimbrook DC, Rockwell S, Sligar SG, Sartorelli AC.
    Cancer Res; 1984 Dec 01; 44(12 Pt 1):5638-43. PubMed ID: 6437671
    [Abstract] [Full Text] [Related]

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  • 20. Bioreductive alkylating agent porfiromycin in combination with radiation therapy for the management of squamous cell carcinoma of the head and neck.
    Haffty BG, Son YH, Wilson LD, Papac R, Fischer D, Rockwell S, Sartorelli AC, Ross D, Sasaki CT, Fischer JJ.
    Radiat Oncol Investig; 1997 Dec 01; 5(5):235-45. PubMed ID: 9372546
    [Abstract] [Full Text] [Related]

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