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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

203 related items for PubMed ID: 7577460

  • 21. Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity.
    Guise CP, Abbattista MR, Anderson RF, Li D, Taghipouran R, Tsai A, Lee SJ, Smaill JB, Denny WA, Hay MP, Wilson WR, Hicks KO, Patterson AV.
    Molecules; 2020 Oct 22; 25(21):. PubMed ID: 33105798
    [Abstract] [Full Text] [Related]

  • 22. Enzymology of the reduction of the novel fused pyrazine mono-n-oxide bioreductive drug, RB90740 roles for P450 reductase and cytochrome b5 reductase.
    Barham HM, Stratford IJ.
    Biochem Pharmacol; 1996 Mar 22; 51(6):829-37. PubMed ID: 8602879
    [Abstract] [Full Text] [Related]

  • 23. Molecular mechanisms of tirapazamine (SR 4233, Win 59075)-induced hepatocyte toxicity under low oxygen concentrations.
    Khan S, O'Brien PJ.
    Br J Cancer; 1995 Apr 22; 71(4):780-5. PubMed ID: 7710944
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  • 24. Direct measurement of pO2 distribution and bioreductive enzymes in human malignant brain tumors.
    Rampling R, Cruickshank G, Lewis AD, Fitzsimmons SA, Workman P.
    Int J Radiat Oncol Biol Phys; 1994 Jun 15; 29(3):427-31. PubMed ID: 8005794
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  • 25. Inhibition of DT-diaphorase (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA): implications for bioreductive drug development.
    Phillips RM.
    Biochem Pharmacol; 1999 Jul 15; 58(2):303-10. PubMed ID: 10423172
    [Abstract] [Full Text] [Related]

  • 26. The role of DT-diaphorase in determining the sensitivity of human tumor cells to tirapazamine (SR 4233).
    Patterson AV, Robertson N, Houlbrook S, Stephens MA, Adams GE, Harris AL, Stratford IJ, Carmichael J.
    Int J Radiat Oncol Biol Phys; 1994 May 15; 29(2):369-72. PubMed ID: 8195035
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  • 27. Selective potentiation of the hypoxic cytotoxicity of tirapazamine by its 1-N-oxide metabolite SR 4317.
    Siim BG, Pruijn FB, Sturman JR, Hogg A, Hay MP, Brown JM, Wilson WR.
    Cancer Res; 2004 Jan 15; 64(2):736-42. PubMed ID: 14744792
    [Abstract] [Full Text] [Related]

  • 28. Oxygen dependence and extravascular transport of hypoxia-activated prodrugs: comparison of the dinitrobenzamide mustard PR-104A and tirapazamine.
    Hicks KO, Myint H, Patterson AV, Pruijn FB, Siim BG, Patel K, Wilson WR.
    Int J Radiat Oncol Biol Phys; 2007 Oct 01; 69(2):560-71. PubMed ID: 17869669
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  • 31. The importance of DT-diaphorase and hypoxia in the cytotoxicity of RH1 in human breast and non-small cell lung cancer cell lines.
    Kim JY, Patterson AV, Stratford IJ, Hendry JH.
    Anticancer Drugs; 2004 Jan 01; 15(1):71-7. PubMed ID: 15090746
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  • 33. Enzymology of tirapazamine metabolism: a review.
    Patterson AV, Saunders MP, Chinje EC, Patterson LH, Stratford IJ.
    Anticancer Drug Des; 1998 Sep 01; 13(6):541-73. PubMed ID: 9755718
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  • 34. Molecular mechanisms of SR 4233-induced hepatocyte toxicity under aerobic versus hypoxic conditions.
    Silva JM, O'Brien PJ.
    Br J Cancer; 1993 Sep 01; 68(3):484-91. PubMed ID: 8394729
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  • 38. Metabolism of tirapazamine by multiple reductases in the nucleus.
    Delahoussaye YM, Evans JW, Brown JM.
    Biochem Pharmacol; 2001 Nov 01; 62(9):1201-9. PubMed ID: 11705453
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  • 40. Protection against SR 4233 (Tirapazamine) aerobic cytotoxicity by the metal chelators desferrioxamine and tiron.
    Herscher LL, Krishna MC, Cook JA, Coleman CN, Biaglow JE, Tuttle SW, Gonzalez FJ, Mitchell JB.
    Int J Radiat Oncol Biol Phys; 1994 Nov 15; 30(4):879-85. PubMed ID: 7960991
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