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Journal Abstract Search

118 related items for PubMed ID: 7577933

  • 1. Mechanism of time-dependent inhibition of 5 alpha-reductases by delta 1-4-azasteroids: toward perfection of rates of time-dependent inhibition by using ligand-binding energies.
    Tian G, Mook RA, Moss ML, Frye SV.
    Biochemistry; 1995 Oct 17; 34(41):13453-9. PubMed ID: 7577933
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  • 2. Linear relationships between the ligand binding energy and the activation energy of time-dependent inhibition of steroid 5alpha-reductase by delta 1-4-azasteroids.
    Tian G, Haffner CD.
    J Biol Chem; 2001 Jun 15; 276(24):21359-64. PubMed ID: 11279132
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  • 3. Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5alpha-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat.
    Stuart JD, Lee FW, Simpson Noel D, Kadwell SH, Overton LK, Hoffman CR, Kost TA, Tippin TK, Yeager RL, Batchelor KW, Bramson HN.
    Biochem Pharmacol; 2001 Oct 01; 62(7):933-42. PubMed ID: 11543729
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  • 4. 17 beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androstan-1-en-3-one is an active site-directed slow time-dependent inhibitor of human steroid 5 alpha-reductase 1.
    Tian G, Stuart JD, Moss ML, Domanico PL, Bramson HN, Patel IR, Kadwell SH, Overton LK, Kost TA, Mook RA.
    Biochemistry; 1994 Mar 01; 33(8):2291-6. PubMed ID: 8117686
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  • 5. Inhibition of human steroid 5alpha reductases type I and II by 6-aza-steroids: structural determinants of one-step vs two-step mechanism.
    Moss ML, Kuzmic P, Stuart JD, Tian G, Peranteau AG, Frye SV, Kadwell SH, Kost TA, Overton LK, Patel IR.
    Biochemistry; 1996 Mar 19; 35(11):3457-64. PubMed ID: 8639496
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  • 9. Inhibition of the activity of 'basic' 5 alpha-reductase (type 1) detected in DU 145 cells and expressed in insect cells.
    Délos S, Iehlé C, Martin PM, Raynaud JP.
    J Steroid Biochem Mol Biol; 1994 Mar 19; 48(4):347-52. PubMed ID: 8142312
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  • 12. 19-nor-10-azasteroids: a novel class of inhibitors for human steroid 5alpha-reductases 1 and 2.
    Guarna A, Belle C, Machetti F, Occhiato EG, Payne AH, Cassiani C, Comerci A, Danza G, De Bellis A, Dini S, Marrucci A, Serio M.
    J Med Chem; 1997 Mar 28; 40(7):1112-29. PubMed ID: 9089333
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  • 18. 4-Methyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-N-aryl-carboxamides: an approach to combined androgen blockade [5alpha-reductase inhibition with androgen receptor binding in vitro].
    Tolman RL, Sahoo SP, Bakshi RK, Gratale D, Patel G, Patel S, Toney J, Chang B, Harris GS.
    J Steroid Biochem Mol Biol; 1997 Mar 28; 60(5-6):303-9. PubMed ID: 9219921
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  • 19. Finasteride: a slow-binding 5 alpha-reductase inhibitor.
    Faller B, Farley D, Nick H.
    Biochemistry; 1993 Jun 01; 32(21):5705-10. PubMed ID: 8389191
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  • 20. Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.
    Xu Y, Dalrymple SL, Becker RE, Denmeade SR, Isaacs JT.
    Clin Cancer Res; 2006 Jul 01; 12(13):4072-9. PubMed ID: 16818707
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