These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

134 related items for PubMed ID: 7582975

  • 1. Crystallographic structure of a peptidyl keto acid inhibitor and human alpha-thrombin.
    Håkansson K, Tulinsky A, Abelman MM, Miller TA, Vlasuk GP, Bergum PW, Lim-Wilby MS, Brunck TK.
    Bioorg Med Chem; 1995 Aug; 3(8):1009-17. PubMed ID: 7582975
    [Abstract] [Full Text] [Related]

  • 2. Amide and alpha-keto carbonyl inhibitors of thrombin based on arginine and lysine: synthesis, stability and biological characterization.
    Brady SF, Sisko JT, Stauffer KJ, Colton CD, Qiu H, Lewis SD, Ng AS, Shafer JA, Bogusky MJ, Veber DF.
    Bioorg Med Chem; 1995 Aug; 3(8):1063-78. PubMed ID: 7582980
    [Abstract] [Full Text] [Related]

  • 3. Crystal structure of a peptidyl pyridinium methyl ketone inhibitor with thrombin.
    Rehse PH, Steinmetzer T, Li Y, Konishi Y, Cygler M.
    Biochemistry; 1995 Sep 12; 34(36):11537-44. PubMed ID: 7547884
    [Abstract] [Full Text] [Related]

  • 4.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 5. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
    Costanzo MJ, Almond HR, Hecker LR, Schott MR, Yabut SC, Zhang HC, Andrade-Gordon P, Corcoran TW, Giardino EC, Kauffman JA, Lewis JM, de Garavilla L, Haertlein BJ, Maryanoff BE.
    J Med Chem; 2005 Mar 24; 48(6):1984-2008. PubMed ID: 15771442
    [Abstract] [Full Text] [Related]

  • 6. Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.
    Nardini M, Pesce A, Rizzi M, Casale E, Ferraccioli R, Balliano G, Milla P, Ascenzi P, Bolognesi M.
    J Mol Biol; 1996 May 24; 258(5):851-9. PubMed ID: 8637015
    [Abstract] [Full Text] [Related]

  • 7.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 8.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 9. Structure of a retro-binding peptide inhibitor complexed with human alpha-thrombin.
    Tabernero L, Chang CY, Ohringer SL, Lau WF, Iwanowicz EJ, Han WC, Wang TC, Seiler SM, Roberts DG, Sack JS.
    J Mol Biol; 1995 Feb 10; 246(1):14-20. PubMed ID: 7853394
    [Abstract] [Full Text] [Related]

  • 10. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
    Bode W, Turk D, Karshikov A.
    Protein Sci; 1992 Apr 10; 1(4):426-71. PubMed ID: 1304349
    [Abstract] [Full Text] [Related]

  • 11.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 12. Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6.
    Zdanov A, Wu S, DiMaio J, Konishi Y, Li Y, Wu X, Edwards BF, Martin PD, Cygler M.
    Proteins; 1993 Nov 10; 17(3):252-65. PubMed ID: 8272424
    [Abstract] [Full Text] [Related]

  • 13. Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.
    Féthière J, Tsuda Y, Coulombe R, Konishi Y, Cygler M.
    Protein Sci; 1996 Jun 10; 5(6):1174-83. PubMed ID: 8762149
    [Abstract] [Full Text] [Related]

  • 14. Peptide-derived transition state analogue inhibitors of thrombin; synthesis, activity and selectivity.
    Jetten M, Peters CA, Visser A, Grootenhuis PD, van Nispen JW, Ottenheijm HC.
    Bioorg Med Chem; 1995 Aug 10; 3(8):1099-114. PubMed ID: 7582983
    [Abstract] [Full Text] [Related]

  • 15. Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics.
    Brandstetter H, Turk D, Hoeffken HW, Grosse D, Stürzebecher J, Martin PD, Edwards BF, Bode W.
    J Mol Biol; 1992 Aug 20; 226(4):1085-99. PubMed ID: 1518046
    [Abstract] [Full Text] [Related]

  • 16. 1,2-disubstituted cyclohexane derived tripeptide aldehydes as novel selective thrombin inhibitors.
    Harmat NJ, Di Bugno C, Criscuoli M, Giorgi R, Lippi A, Martinelli A, Monti S, Subissi A.
    Bioorg Med Chem Lett; 1998 May 19; 8(10):1249-54. PubMed ID: 9871744
    [Abstract] [Full Text] [Related]

  • 17. Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.
    Qiu X, Padmanabhan KP, Carperos VE, Tulinsky A, Kline T, Maraganore JM, Fenton JW.
    Biochemistry; 1992 Dec 01; 31(47):11689-97. PubMed ID: 1445905
    [Abstract] [Full Text] [Related]

  • 18.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 19.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 20.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 7.