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Journal Abstract Search
115 related items for PubMed ID: 7582977
1. Cyclotheonamide derivatives: synthesis and thrombin inhibition. Exploration of specific structure-function issues. Maryanoff BE, Zhang HC, Greco MN, Glover KA, Kauffman JA, Andrade-Gordon P. Bioorg Med Chem; 1995 Aug; 3(8):1025-38. PubMed ID: 7582977 [Abstract] [Full Text] [Related]
2. Molecular basis for the inhibition of human alpha-thrombin by the macrocyclic peptide cyclotheonamide A. Maryanoff BE, Qiu X, Padmanabhan KP, Tulinsky A, Almond HR, Andrade-Gordon P, Greco MN, Kauffman JA, Nicolaou KC, Liu A. Proc Natl Acad Sci U S A; 1993 Sep 01; 90(17):8048-52. PubMed ID: 8367461 [Abstract] [Full Text] [Related]
3. Amide and alpha-keto carbonyl inhibitors of thrombin based on arginine and lysine: synthesis, stability and biological characterization. Brady SF, Sisko JT, Stauffer KJ, Colton CD, Qiu H, Lewis SD, Ng AS, Shafer JA, Bogusky MJ, Veber DF. Bioorg Med Chem; 1995 Aug 01; 3(8):1063-78. PubMed ID: 7582980 [Abstract] [Full Text] [Related]
7. Peptide-derived transition state analogue inhibitors of thrombin; synthesis, activity and selectivity. Jetten M, Peters CA, Visser A, Grootenhuis PD, van Nispen JW, Ottenheijm HC. Bioorg Med Chem; 1995 Aug 01; 3(8):1099-114. PubMed ID: 7582983 [Abstract] [Full Text] [Related]
16. Active site-directed thrombin inhibitors: alpha-hydroxyacyl-prolyl-arginals. New orally active stable analogs of D-Phe-Pro-Arg-H. Bajusz S, Barabás E, Fauszt I, Fehér A, Horváth G, Juhász A, Szabó AG, Széll E. Bioorg Med Chem; 1995 Aug 19; 3(8):1079-89. PubMed ID: 7582981 [Abstract] [Full Text] [Related]
18. Active site-directed thrombin inhibitors--II. Studies related to arginine/guanidine bioisosteres. St Laurent DR, Balasubramanian N, Han WT, Trehan A, Federici ME, Meanwell NA, Wright JJ, Seiler SM. Bioorg Med Chem; 1995 Aug 19; 3(8):1145-56. PubMed ID: 7582986 [Abstract] [Full Text] [Related]
19. Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin. Hanessian S, Ersmark K, Wang X, Del Valle JR, Blomberg N, Xue Y, Fjellström O. Bioorg Med Chem Lett; 2007 Jun 15; 17(12):3480-5. PubMed ID: 17428662 [Abstract] [Full Text] [Related]