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81 related items for PubMed ID: 7583212

  • 1. Haloperidol and reduced haloperidol-induced exacerbation of the dystonia produced by the kappa opioid U50,488H in guinea-pigs is associated with inhibition of sigma binding sites: behavioural and autoradiographical studies.
    Brent PJ.
    Brain Res; 1995 Jul 03; 684(2):115-26. PubMed ID: 7583212
    [Abstract] [Full Text] [Related]

  • 2. Kappa opioid receptor agonists inhibit sigma-1 (sigma 1) receptor binding in guinea-pig brain, liver and spleen: autoradiographical evidence.
    Brent PJ.
    Brain Res; 1996 Jul 01; 725(2):155-65. PubMed ID: 8836521
    [Abstract] [Full Text] [Related]

  • 3. Behavioural effect of pretreatment with opioid antagonists and sigma binding site ligands on the abnormal motor response produced by the kappa opioid agonist U50,488H in guinea pigs.
    Brent PJ.
    Neuropharmacology; 1993 Aug 01; 32(8):751-60. PubMed ID: 8413839
    [Abstract] [Full Text] [Related]

  • 4. Probes for narcotic receptor mediated phenomena. 17. Synthesis and evaluation of a series of trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacet amide (U50,488) related isothiocyanate derivatives as opioid receptor affinity ligands.
    de Costa BR, Rothman RB, Bykov V, Band L, Pert A, Jacobson AE, Rice KC.
    J Med Chem; 1990 Apr 01; 33(4):1171-6. PubMed ID: 2157008
    [Abstract] [Full Text] [Related]

  • 5. Sex difference in κ-opioid receptor (KOPR)-mediated behaviors, brain region KOPR level and KOPR-mediated guanosine 5'-O-(3-[35S]thiotriphosphate) binding in the guinea pig.
    Wang YJ, Rasakham K, Huang P, Chudnovskaya D, Cowan A, Liu-Chen LY.
    J Pharmacol Exp Ther; 2011 Nov 01; 339(2):438-50. PubMed ID: 21841040
    [Abstract] [Full Text] [Related]

  • 6. The kappa-opioid receptor agonist, U50,488H, exerts antidystonic activity in a mutant hamster model of generalized dystonia.
    Richter A, Löscher W.
    Eur J Pharmacol; 1993 May 19; 236(2):289-94. PubMed ID: 8391460
    [Abstract] [Full Text] [Related]

  • 7. The kappa-opioid receptor agonist U50,488H induces acute physical dependence in guinea-pigs.
    Brent PJ, Chahl LA, Cantarell PA, Kavanagh C.
    Eur J Pharmacol; 1993 Sep 14; 241(2-3):149-56. PubMed ID: 7902288
    [Abstract] [Full Text] [Related]

  • 8. Alterations in the stereochemistry of the kappa-selective opioid agonist U50,488 result in high-affinity sigma ligands.
    de Costa BR, Bowen WD, Hellewell SB, George C, Rothman RB, Reid AA, Walker JM, Jacobson AE, Rice KC.
    J Med Chem; 1989 Aug 14; 32(8):1996-2002. PubMed ID: 2547074
    [Abstract] [Full Text] [Related]

  • 9. Pharmacological activities of optically pure enantiomers of the kappa opioid agonist, U50,488, and its cis diastereomer: evidence for three kappa receptor subtypes.
    Rothman RB, France CP, Bykov V, De Costa BR, Jacobson AE, Woods JH, Rice KC.
    Eur J Pharmacol; 1989 Aug 29; 167(3):345-53. PubMed ID: 2553442
    [Abstract] [Full Text] [Related]

  • 10. Effects of chronic U50,488H treatment on binding and mechanical responses of the rat hearts.
    Xia Q, Sheng JZ, Tai KK, Wong TM.
    J Pharmacol Exp Ther; 1994 Feb 29; 268(2):930-4. PubMed ID: 8114007
    [Abstract] [Full Text] [Related]

  • 11. Effects of prior exposure to morphine on the opioid inhibition of the stimulated release of [3H]norepinephrine from guinea pig cortex slices.
    Werling LL, Brown SR, Cox BM.
    NIDA Res Monogr; 1986 Feb 29; 75():587-90. PubMed ID: 2829006
    [Abstract] [Full Text] [Related]

  • 12. Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands.
    Zhu J, Luo LY, Li JG, Chen C, Liu-Chen LY.
    J Pharmacol Exp Ther; 1997 Aug 29; 282(2):676-84. PubMed ID: 9262330
    [Abstract] [Full Text] [Related]

  • 13. Effect of chronic administration of U-50,488H on tolerance to its pharmacological actions and on multiple opioid receptors in rat brain regions and spinal cord.
    Bhargava HN, Gulati A, Ramarao P.
    J Pharmacol Exp Ther; 1989 Oct 29; 251(1):21-6. PubMed ID: 2552075
    [Abstract] [Full Text] [Related]

  • 14. The effects of dynorphin A (1-13) and U50, 488H on free intracellular calcium in guinea pig cerebellar synaptosomes.
    Olson KG, Welch SP.
    Life Sci; 1991 Oct 29; 48(6):575-81. PubMed ID: 1671526
    [Abstract] [Full Text] [Related]

  • 15. Kappa opioid receptor tolerance in the guinea pig hippocampus.
    Jin W, Terman GW, Chavkin C.
    J Pharmacol Exp Ther; 1997 Apr 29; 281(1):123-8. PubMed ID: 9103488
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of [3H]-U69593 binding and the cardiac effects of U50, 488H by calcium channel blockers in the rat heart.
    Zhang WM, Wang HX, Xia Q, Wong TM.
    Br J Pharmacol; 1997 Mar 29; 120(5):827-32. PubMed ID: 9138688
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of interleukin-1 and tumor necrosis factor-alpha synthesis following treatment of macrophages with the kappa opioid agonist U50, 488H.
    Belkowski SM, Alicea C, Eisenstein TK, Adler MW, Rogers TJ.
    J Pharmacol Exp Ther; 1995 Jun 29; 273(3):1491-6. PubMed ID: 7791124
    [Abstract] [Full Text] [Related]

  • 18. Sex differences in U50,488H-induced phosphorylation of p44/42 mitogen-activated protein kinase in the guinea pig brain.
    Rasakham K, McGillivray KL, Liu-Chen LY.
    Neuroscience; 2012 Oct 25; 223():447-56. PubMed ID: 22863678
    [Abstract] [Full Text] [Related]

  • 19. Haloperidol pretreatment unmasks the kappa opioid effects of U-50, 488H on cortical EEG and EEG power spectra in rats.
    Young GA, Marquis KL, Paquette NC, Gussio RP, Khazan N.
    Neuropharmacology; 1989 Aug 25; 28(8):881-4. PubMed ID: 2550842
    [Abstract] [Full Text] [Related]

  • 20. In vivo treatment with mu and delta, but not kappa-selective opioid agonists reduces [3H]spiperone binding to the guinea-pig striatum: autoradiographic evidence.
    Brent PJ, Bunn SJ.
    Brain Res; 1994 Aug 22; 654(2):191-9. PubMed ID: 7987668
    [Abstract] [Full Text] [Related]

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