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Journal Abstract Search

216 related items for PubMed ID: 7587944

  • 1. Metabolism of terfenadine associated with CYP3A(4) activity in human hepatic microsomes.
    Ling KH, Leeson GA, Burmaster SD, Hook RH, Reith MK, Cheng LK.
    Drug Metab Dispos; 1995 Jun; 23(6):631-6. PubMed ID: 7587944
    [Abstract] [Full Text] [Related]

  • 2. Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals.
    Jurima-Romet M, Crawford K, Cyr T, Inaba T.
    Drug Metab Dispos; 1994 Jun; 22(6):849-57. PubMed ID: 7895601
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of phencyclidine by human liver microsomes.
    Laurenzana EM, Owens SM.
    Drug Metab Dispos; 1997 May; 25(5):557-63. PubMed ID: 9152594
    [Abstract] [Full Text] [Related]

  • 4. Comparison of CYP3A activities in a subclone of Caco-2 cells (TC7) and human intestine.
    Raeissi SD, Guo Z, Dobson GL, Artursson P, Hidalgo IJ.
    Pharm Res; 1997 Aug; 14(8):1019-25. PubMed ID: 9279883
    [Abstract] [Full Text] [Related]

  • 5. Differential metabolism of midazolam in mouse liver and intestine microsomes: a comparison of cytochrome P450 activity and expression.
    Perloff MD, Von Moltke LL, Greenblatt DJ.
    Xenobiotica; 2003 Apr; 33(4):365-77. PubMed ID: 12745872
    [Abstract] [Full Text] [Related]

  • 6. Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation.
    Yun CH, Okerholm RA, Guengerich FP.
    Drug Metab Dispos; 1993 Apr; 21(3):403-9. PubMed ID: 8100494
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme.
    Harris JW, Rahman A, Kim BR, Guengerich FP, Collins JM.
    Cancer Res; 1994 Aug 01; 54(15):4026-35. PubMed ID: 7913410
    [Abstract] [Full Text] [Related]

  • 8. Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms.
    Perloff MD, von Moltke LL, Court MH, Kotegawa T, Shader RI, Greenblatt DJ.
    J Pharmacol Exp Ther; 2000 Feb 01; 292(2):618-28. PubMed ID: 10640299
    [Abstract] [Full Text] [Related]

  • 9. In vitro biotransformation and identification of human cytochrome P450 isozyme-dependent metabolism of tazofelone.
    Surapaneni SS, Clay MP, Spangle LA, Paschal JW, Lindstrom TD.
    Drug Metab Dispos; 1997 Dec 01; 25(12):1383-8. PubMed ID: 9394028
    [Abstract] [Full Text] [Related]

  • 10. Development of a non-high pressure liquid chromatography assay to determine testosterone hydroxylase (CYP3A) activity in human liver microsomes.
    Draper AJ, Madan A, Smith K, Parkinson A.
    Drug Metab Dispos; 1998 Apr 01; 26(4):299-304. PubMed ID: 9531515
    [Abstract] [Full Text] [Related]

  • 11. Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions.
    Zhou-Pan XR, Sérée E, Zhou XJ, Placidi M, Maurel P, Barra Y, Rahmani R.
    Cancer Res; 1993 Nov 01; 53(21):5121-6. PubMed ID: 8221648
    [Abstract] [Full Text] [Related]

  • 12. Induction of CYP3A and associated terfenadine N-dealkylation in rat hepatocytes cocultured with 3T3 cells.
    Jurima-Romet M, Casley WL, Neu JM, Huang HS.
    Cell Biol Toxicol; 1995 Dec 01; 11(6):313-27. PubMed ID: 8788208
    [Abstract] [Full Text] [Related]

  • 13. Ropivacaine, a new amide-type local anesthetic agent, is metabolized by cytochromes P450 1A and 3A in human liver microsomes.
    Ekström G, Gunnarsson UB.
    Drug Metab Dispos; 1996 Sep 01; 24(9):955-61. PubMed ID: 8886604
    [Abstract] [Full Text] [Related]

  • 14. In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.
    Rodrigues AD, Mulford DJ, Lee RD, Surber BW, Kukulka MJ, Ferrero JL, Thomas SB, Shet MS, Estabrook RW.
    Drug Metab Dispos; 1995 Jul 01; 23(7):765-75. PubMed ID: 7587966
    [Abstract] [Full Text] [Related]

  • 15. The roles of CYP3A and CYP2B isoforms in hepatic bioactivation and detoxification of the pyrrolizidine alkaloid senecionine in sheep and hamsters.
    Huan JY, Miranda CL, Buhler DR, Cheeke PR.
    Toxicol Appl Pharmacol; 1998 Aug 01; 151(2):229-35. PubMed ID: 9707499
    [Abstract] [Full Text] [Related]

  • 16. Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
    Gallagher EP, Wienkers LC, Stapleton PL, Kunze KL, Eaton DL.
    Cancer Res; 1994 Jan 01; 54(1):101-8. PubMed ID: 8261428
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.
    Lampen A, Christians U, Guengerich FP, Watkins PB, Kolars JC, Bader A, Gonschior AK, Dralle H, Hackbarth I, Sewing KF.
    Drug Metab Dispos; 1995 Dec 01; 23(12):1315-24. PubMed ID: 8689938
    [Abstract] [Full Text] [Related]

  • 18. Studies on the cytochrome P450 (CYP)-mediated metabolic properties of miocamycin: evaluation of the possibility of a metabolic intermediate complex formation with CYP, and identification of the human CYP isoforms.
    Kasahara M, Suzuki H, Komiya I.
    Drug Metab Dispos; 2000 Apr 01; 28(4):409-17. PubMed ID: 10725309
    [Abstract] [Full Text] [Related]

  • 19. Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver.
    Jönsson G, Aström A, Andersson P.
    Drug Metab Dispos; 1995 Jan 01; 23(1):137-42. PubMed ID: 7720517
    [Abstract] [Full Text] [Related]

  • 20. Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone.
    Mäenpää J, Hall SD, Ring BJ, Strom SC, Wrighton SA.
    Pharmacogenetics; 1998 Apr 01; 8(2):137-55. PubMed ID: 10022752
    [Abstract] [Full Text] [Related]

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