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Journal Abstract Search

216 related items for PubMed ID: 7587944

  • 21. Description of a 96-well plate assay to measure cytochrome P4503A inhibition in human liver microsomes using a selective fluorescent probe.
    Chauret N, Tremblay N, Lackman RL, Gauthier JY, Silva JM, Marois J, Yergey JA, Nicoll-Griffith DA.
    Anal Biochem; 1999 Dec 15; 276(2):215-26. PubMed ID: 10603245
    [Abstract] [Full Text] [Related]

  • 22. Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver.
    Jacobsen W, Kirchner G, Hallensleben K, Mancinelli L, Deters M, Hackbarth I, Benet LZ, Sewing KF, Christians U.
    Drug Metab Dispos; 1999 Feb 15; 27(2):173-9. PubMed ID: 9929499
    [Abstract] [Full Text] [Related]

  • 23. Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions.
    Labroo RB, Paine MF, Thummel KE, Kharasch ED.
    Drug Metab Dispos; 1997 Sep 15; 25(9):1072-80. PubMed ID: 9311623
    [Abstract] [Full Text] [Related]

  • 24. Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism.
    Fitzsimmons ME, Collins JM.
    Drug Metab Dispos; 1997 Feb 15; 25(2):256-66. PubMed ID: 9029057
    [Abstract] [Full Text] [Related]

  • 25. Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine.
    Matsumoto S, Yamazoe Y.
    Br J Clin Pharmacol; 2001 Feb 15; 51(2):133-42. PubMed ID: 11259984
    [Abstract] [Full Text] [Related]

  • 26. Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes.
    Klees TM, Sheffels P, Dale O, Kharasch ED.
    Drug Metab Dispos; 2005 Mar 15; 33(3):303-11. PubMed ID: 15557344
    [Abstract] [Full Text] [Related]

  • 27. Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
    Madan A, Parkinson A, Faiman MD.
    Alcohol Clin Exp Res; 1998 Sep 15; 22(6):1212-9. PubMed ID: 9756035
    [Abstract] [Full Text] [Related]

  • 28. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T, Shiraga T, Mitani Y, Terakawa M, Tokuma Y, Kagayama A.
    Drug Metab Dispos; 2000 Sep 15; 28(9):1128-34. PubMed ID: 10950860
    [Abstract] [Full Text] [Related]

  • 29. Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.
    Pearce RE, Gotschall RR, Kearns GL, Leeder JS.
    Drug Metab Dispos; 2001 Dec 15; 29(12):1548-54. PubMed ID: 11717173
    [Abstract] [Full Text] [Related]

  • 30. Oxidative metabolism of zolpidem by human liver cytochrome P450S.
    Pichard L, Gillet G, Bonfils C, Domergue J, Thénot JP, Maurel P.
    Drug Metab Dispos; 1995 Nov 15; 23(11):1253-62. PubMed ID: 8591727
    [Abstract] [Full Text] [Related]

  • 31. Biosynthesis of an aminopiperidino metabolite of irinotecan [7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecine] by human hepatic microsomes.
    Haaz MC, Riché C, Rivory LP, Robert J.
    Drug Metab Dispos; 1998 Aug 15; 26(8):769-74. PubMed ID: 9698291
    [Abstract] [Full Text] [Related]

  • 32. Metabolism of epinastine, a histamine H1 receptor antagonist, in human liver microsomes in comparison with that of terfenadine.
    Kishimoto W, Hiroi T, Sakai K, Funae Y, Igarashi T.
    Res Commun Mol Pathol Pharmacol; 1997 Dec 15; 98(3):273-92. PubMed ID: 9485522
    [Abstract] [Full Text] [Related]

  • 33. Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
    Raeissi SD, Hidalgo IJ, Segura-Aguilar J, Artursson P.
    Pharm Res; 1999 May 15; 16(5):625-32. PubMed ID: 10350002
    [Abstract] [Full Text] [Related]

  • 34. The aliphatic oxidation of salmeterol to alpha-hydroxysalmeterol in human liver microsomes is catalyzed by CYP3A.
    Manchee GR, Eddershaw PJ, Ranshaw LE, Herriott D, Park GR, Bayliss MK, Tarbit MH.
    Drug Metab Dispos; 1996 May 15; 24(5):555-9. PubMed ID: 8723736
    [Abstract] [Full Text] [Related]

  • 35. Effect of dirithromycin on human CYP3A in vitro and on pharmacokinetics and pharmacodynamics of terfenadine in vivo.
    Goldberg MJ, Ring B, DeSante K, Cerimele B, Hatcher B, Sides G, Wrighton S.
    J Clin Pharmacol; 1996 Dec 15; 36(12):1154-60. PubMed ID: 9013373
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  • 36. Identification of cytochromes P450 involved in human liver microsomal metabolism of ecabapide, a prokinetic agent.
    Fujimaki Y, Arai N, Inaba T.
    Xenobiotica; 1999 Dec 15; 29(12):1273-82. PubMed ID: 10647912
    [Abstract] [Full Text] [Related]

  • 37. Catalytic role of cytochrome P4503A4 in multiple pathways of alfentanil metabolism.
    Labroo RB, Thummel KE, Kunze KL, Podoll T, Trager WF, Kharasch ED.
    Drug Metab Dispos; 1995 Apr 15; 23(4):490-6. PubMed ID: 7600917
    [Abstract] [Full Text] [Related]

  • 38. In vitro metabolism of testosterone in the horse liver and involvement of equine CYPs 3A89, 3A94 and 3A95.
    Schmitz A, Zielinski J, Dick B, Mevissen M.
    J Vet Pharmacol Ther; 2014 Aug 15; 37(4):338-47. PubMed ID: 24479850
    [Abstract] [Full Text] [Related]

  • 39. Terfenadine-antidepressant interactions: an in vitro inhibition study using human liver microsomes.
    Jurima-Romet M, Wright M, Neigh S.
    Br J Clin Pharmacol; 1998 Mar 15; 45(3):318-21. PubMed ID: 10896409
    [Abstract] [Full Text] [Related]

  • 40. CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes.
    Cao YF, Zhang YY, Li J, Ge GB, Hu D, Liu HX, Huang T, Wang YC, Fang ZZ, Sun DX, Huo H, Yin J, Yang L.
    Xenobiotica; 2010 Jan 15; 40(1):38-47. PubMed ID: 20001672
    [Abstract] [Full Text] [Related]

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