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Journal Abstract Search

212 related items for PubMed ID: 7592913

  • 21. MEK and ERK activation in ras-disabled RBL-2H3 mast cells and novel roles for geranylgeranylated and farnesylated proteins in Fc epsilonRI-mediated signaling.
    Graham TE, Pfeiffer JR, Lee RJ, Kusewitt DF, Martinez AM, Foutz T, Wilson BS, Oliver JM.
    J Immunol; 1998 Dec 15; 161(12):6733-44. PubMed ID: 9862703
    [Abstract] [Full Text] [Related]

  • 22. K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors.
    Whyte DB, Kirschmeier P, Hockenberry TN, Nunez-Oliva I, James L, Catino JJ, Bishop WR, Pai JK.
    J Biol Chem; 1997 May 30; 272(22):14459-64. PubMed ID: 9162087
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  • 23. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
    Alcock RA, Dey S, Chendil D, Inayat MS, Mohiuddin M, Hartman G, Chatfield LK, Gallicchio VS, Ahmed MM.
    Oncogene; 2002 Nov 07; 21(51):7883-90. PubMed ID: 12420225
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  • 24. Pseudodipeptide inhibitors of protein farnesyltransferase.
    deSolms SJ, Deana AA, Giuliani EA, Graham SL, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Scholz TH.
    J Med Chem; 1995 Sep 29; 38(20):3967-71. PubMed ID: 7562930
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  • 26. Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells.
    Manne V, Yan N, Carboni JM, Tuomari AV, Ricca CS, Brown JG, Andahazy ML, Schmidt RJ, Patel D, Zahler R.
    Oncogene; 1995 May 04; 10(9):1763-79. PubMed ID: 7753553
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  • 28. Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I.
    Vasudevan A, Qian Y, Vogt A, Blaskovich MA, Ohkanda J, Sebti SM, Hamilton AD.
    J Med Chem; 1999 Apr 22; 42(8):1333-40. PubMed ID: 10212118
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  • 30. A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines.
    Sepp-Lorenzino L, Ma Z, Rands E, Kohl NE, Gibbs JB, Oliff A, Rosen N.
    Cancer Res; 1995 Nov 15; 55(22):5302-9. PubMed ID: 7585592
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  • 31. Inhibition of Ras and related guanosine triphosphate-dependent proteins as a therapeutic strategy for blocking malignant glioma growth: II--preclinical studies in a nude mouse model.
    Pollack IF, Bredel M, Erff M, Hamilton AD, Sebti SM.
    Neurosurgery; 1999 Nov 15; 45(5):1208-14; discussion 1214-5. PubMed ID: 10549939
    [Abstract] [Full Text] [Related]

  • 32. Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity.
    Leftheris K, Kline T, Vite GD, Cho YH, Bhide RS, Patel DV, Patel MM, Schmidt RJ, Weller HN, Andahazy ML, Carboni JM, Gullo-Brown JL, Lee FY, Ricca C, Rose WC, Yan N, Barbacid M, Hunt JT, Meyers CA, Seizinger BR, Zahler R, Manne V.
    J Med Chem; 1996 Jan 05; 39(1):224-36. PubMed ID: 8568812
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  • 33. The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner.
    Vogt A, Sun J, Qian Y, Hamilton AD, Sebti SM.
    J Biol Chem; 1997 Oct 24; 272(43):27224-9. PubMed ID: 9341167
    [Abstract] [Full Text] [Related]

  • 34. Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells.
    Lu J, Yoshimura K, Goto K, Lee C, Hamura K, Kwon O, Tamanoi F.
    PLoS One; 2015 Oct 24; 10(9):e0137595. PubMed ID: 26352258
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  • 36. Inhibiting geranylgeranylation blocks growth and promotes apoptosis in pulmonary vascular smooth muscle cells.
    Stark WW, Blaskovich MA, Johnson BA, Qian Y, Vasudevan A, Pitt B, Hamilton AD, Sebti SM, Davies P.
    Am J Physiol; 1998 Jul 24; 275(1):L55-63. PubMed ID: 9688935
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  • 39. Peptide specificity of protein prenyltransferases is determined mainly by reactivity rather than binding affinity.
    Hartman HL, Hicks KA, Fierke CA.
    Biochemistry; 2005 Nov 22; 44(46):15314-24. PubMed ID: 16285735
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  • 40. Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth.
    Falsetti SC, Wang DA, Peng H, Carrico D, Cox AD, Der CJ, Hamilton AD, Sebti SM.
    Mol Cell Biol; 2007 Nov 22; 27(22):8003-14. PubMed ID: 17875936
    [Abstract] [Full Text] [Related]

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