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94 related items for PubMed ID: 7598698

  • 1. Chimeric receptors expressing juxtamembrane sequences of the insulin receptor undergo rapid endocytosis in the absence of receptor tyrosine kinase activity.
    Rajagopalan M, Hebert L, McClain DA.
    Biochem Biophys Res Commun; 1995 Jun 26; 211(3):714-8. PubMed ID: 7598698
    [Abstract] [Full Text] [Related]

  • 2. Insulin internalization in the absence of the insulin receptor tyrosine kinase domain is insufficient for mediating intracellular biological effects.
    Schranz DB, Rohilla AM, Anderson C, Wood WM, Berhanu P.
    Biochem Biophys Res Commun; 1996 Oct 14; 227(2):600-7. PubMed ID: 8878559
    [Abstract] [Full Text] [Related]

  • 3. The amino acid sequence GPLY is not necessary for normal endocytosis of the human insulin receptor B isoform.
    Berhanu P, Anderson C, Paynter DR, Wood WM.
    Biochem Biophys Res Commun; 1995 Apr 17; 209(2):730-8. PubMed ID: 7537496
    [Abstract] [Full Text] [Related]

  • 4. Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors.
    Nakashima S, Morinaka K, Koyama S, Ikeda M, Kishida M, Okawa K, Iwamatsu A, Kishida S, Kikuchi A.
    EMBO J; 1999 Jul 01; 18(13):3629-42. PubMed ID: 10393179
    [Abstract] [Full Text] [Related]

  • 5. Decrease in the insulin receptor protein level by anti-insulin receptor antibodies: roles of tyrosine kinase activity and receptor internalization.
    Fujita N, Yamasaki H, Yamakawa K, Uotani S, Kuwahara H, Degawa-Yamauchi M, Abe T, Ozaki M, Sera Y, Kawasaki E, Takino H, Yamaguchi Y, Eguchi K.
    Acta Diabetol; 2002 Dec 01; 39(4):221-7. PubMed ID: 12486497
    [Abstract] [Full Text] [Related]

  • 6. Antiapoptotic signaling by the insulin receptor in Chinese hamster ovary cells.
    Lee-Kwon W, Park D, Baskar PV, Kole S, Bernier M.
    Biochemistry; 1998 Nov 10; 37(45):15747-57. PubMed ID: 9843380
    [Abstract] [Full Text] [Related]

  • 7. Amino acid sequences Gly-Pro-Leu-Tyr and Asn-Pro-Glu-Tyr in the submembranous domain of the insulin receptor are required for normal endocytosis.
    Rajagopalan M, Neidigh JL, McClain DA.
    J Biol Chem; 1991 Dec 05; 266(34):23068-73. PubMed ID: 1744103
    [Abstract] [Full Text] [Related]

  • 8. A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high affinity interaction with p59fyn.
    Ellis C, Kasmi F, Ganju P, Walls E, Panayotou G, Reith AD.
    Oncogene; 1996 Apr 18; 12(8):1727-36. PubMed ID: 8622893
    [Abstract] [Full Text] [Related]

  • 9. An arginine to cysteine(252) mutation in insulin receptors from a patient with severe insulin resistance inhibits receptor internalisation but preserves signalling events.
    Hamer I, Foti M, Emkey R, Cordier-Bussat M, Philippe J, De Meyts P, Maeder C, Kahn CR, Carpentier JL.
    Diabetologia; 2002 May 18; 45(5):657-67. PubMed ID: 12107746
    [Abstract] [Full Text] [Related]

  • 10. The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimerae is internalization impaired.
    Sorkin A, Di Fiore PP, Carpenter G.
    Oncogene; 1993 Nov 18; 8(11):3021-8. PubMed ID: 8105439
    [Abstract] [Full Text] [Related]

  • 11. Identification of structural characteristics that contribute to a difference in antiapoptotic function between human insulin and insulin-like growth factor 1 receptors.
    Chen H, Yan GC, Gishizky ML.
    Cell Growth Differ; 1998 Nov 18; 9(11):939-47. PubMed ID: 9831246
    [Abstract] [Full Text] [Related]

  • 12. Molecular and cellular mechanisms governing the ligand-specific and non-specific steps of insulin receptor internalization.
    Carpentier JL, Hamer I, Gilbert A, Paccaud JP.
    Z Gastroenterol; 1996 Jun 18; 34 Suppl 3():73-5. PubMed ID: 8767469
    [Abstract] [Full Text] [Related]

  • 13. Asn229 in the third helix of VPAC1 receptor is essential for receptor activation but not for receptor phosphorylation and internalization: comparison with Asn216 in VPAC2 receptor.
    Nachtergael I, Gaspard N, Langlet C, Robberecht P, Langer I.
    Cell Signal; 2006 Dec 18; 18(12):2121-30. PubMed ID: 16650965
    [Abstract] [Full Text] [Related]

  • 14. Insulin inhibition of protein degradation in cells expressing wild-type and mutant insulin receptors.
    Hamel FG, Fawcett J, Andersen CI, Berhanu P, Bennett RG, Duckworth WC.
    J Endocrinol Invest; 2003 Nov 18; 26(11):1088-94. PubMed ID: 15008246
    [Abstract] [Full Text] [Related]

  • 15. NPXY motif in the insulin-like growth factor-I receptor is required for efficient ligand-mediated receptor internalization and biological signaling.
    Hsu D, Knudson PE, Zapf A, Rolband GC, Olefsky JM.
    Endocrinology; 1994 Feb 18; 134(2):744-50. PubMed ID: 8299569
    [Abstract] [Full Text] [Related]

  • 16. The NPEY sequence is not necessary for endocytosis and processing of insulin-receptor complexes.
    Berhanu P, Ibrahim-Schneck RH, Anderson C, Wood WM.
    Mol Endocrinol; 1991 Dec 18; 5(12):1827-35. PubMed ID: 1791832
    [Abstract] [Full Text] [Related]

  • 17. Replacement of the human insulin receptor transmembrane and cytoplasmic domains by corresponding domains of the oncogene product v-ros leads to accelerated internalization, degradation, and down-regulation.
    Berhanu P, Rohilla AM, Rutter WJ.
    J Biol Chem; 1990 Jun 05; 265(16):9505-11. PubMed ID: 2188977
    [Abstract] [Full Text] [Related]

  • 18. Receptor-mediated internalization of insulin requires a 12-amino acid sequence in the juxtamembrane region of the insulin receptor beta-subunit.
    Backer JM, Kahn CR, Cahill DA, Ullrich A, White MF.
    J Biol Chem; 1990 Sep 25; 265(27):16450-4. PubMed ID: 2204623
    [Abstract] [Full Text] [Related]

  • 19. A truncated human insulin receptor missing the COOH-terminal 365 amino acid residues does not undergo insulin-mediated receptor migration or aggregation.
    Smith RM, Sasaoka T, Shah N, Takata Y, Kusari J, Olefsky JM, Jarett L.
    Endocrinology; 1993 Apr 25; 132(4):1453-62. PubMed ID: 8462446
    [Abstract] [Full Text] [Related]

  • 20. Phosphorylation of membrane proteins in monensin-resistant mutant of Chinese hamster ovary cell with altered insulin-receptor activity.
    Ono M, Takahashi K, Sato Y, Kuwano M.
    Biochem Int; 1984 Sep 25; 9(3):369-77. PubMed ID: 6508814
    [Abstract] [Full Text] [Related]

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