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508 related items for PubMed ID: 7603461

  • 1. 2-Hydroxyethyl-alpha-D-glucopyranoside-2,3',4'-trisphosphate, a novel, metabolically resistant, adenophostin A and myo-inositol-1,4,5-trisphosphate analogue, potently interacts with the myo-inositol-1,4,5-trisphosphate receptor.
    Wilcox RA, Erneux C, Primrose WU, Gigg R, Nahorski SR.
    Mol Pharmacol; 1995 Jun; 47(6):1204-11. PubMed ID: 7603461
    [Abstract] [Full Text] [Related]

  • 2. Structural analogues of D-myo-inositol-1,4,5-trisphosphate and adenophostin A: recognition by cerebellar and platelet inositol-1,4,5-trisphosphate receptors.
    Murphy CT, Riley AM, Lindley CJ, Jenkins DJ, Westwick J, Potter BV.
    Mol Pharmacol; 1997 Oct; 52(4):741-8. PubMed ID: 9380038
    [Abstract] [Full Text] [Related]

  • 3. Modification at C2 of myo-inositol 1,4,5-trisphosphate produces inositol trisphosphates and tetrakisphosphates with potent biological activities.
    Wilcox RA, Safrany ST, Lampe D, Mills SJ, Nahorski SR, Potter BV.
    Eur J Biochem; 1994 Jul 01; 223(1):115-24. PubMed ID: 8033885
    [Abstract] [Full Text] [Related]

  • 4. Disaccharide polyphosphates based upon adenophostin A activate hepatic D-myo-inositol 1,4,5-trisphosphate receptors.
    Marchant JS, Beecroft MD, Riley AM, Jenkins DJ, Marwood RD, Taylor CW, Potter BV.
    Biochemistry; 1997 Oct 21; 36(42):12780-90. PubMed ID: 9335535
    [Abstract] [Full Text] [Related]

  • 5. Inositol-1,3,4,5-tetrakisphosphate induces calcium mobilization via the inositol-1,4,5-trisphosphate receptor in SH-SY5Y neuroblastoma cells.
    Wilcox RA, Challiss RA, Liu C, Potter BV, Nahorski SR.
    Mol Pharmacol; 1993 Oct 21; 44(4):810-7. PubMed ID: 8232232
    [Abstract] [Full Text] [Related]

  • 6. Defining the minimal structural requirements for partial agonism at the type I myo-inositol 1,4,5-trisphosphate receptor.
    Wilcox RA, Fauq A, Kozikowski AP, Nahorski SR.
    FEBS Lett; 1997 Feb 03; 402(2-3):241-5. PubMed ID: 9037203
    [Abstract] [Full Text] [Related]

  • 7. Interaction of synthetic D-6-deoxy-myo-inositol 1,4,5-trisphosphate with the Ca2(+)-releasing D-myo-inositol 1,4,5-trisphosphate receptor, and the metabolic enzymes 5-phosphatase and 3-kinase.
    Safrany ST, Wojcikiewicz RJ, Strupish J, Nahorski SR, Dubreuil D, Cleophax J, Gero SD, Potter BV.
    FEBS Lett; 1991 Jan 28; 278(2):252-6. PubMed ID: 1846823
    [Abstract] [Full Text] [Related]

  • 8. Myo-inositol 1,3,4,5-tetrakisphosphate can independently mobilise intracellular calcium, via the inositol 1,4,5-trisphosphate receptor: studies with myo-inositol 1,4,5-trisphosphate-3-phosphorothioate and myo-inositol hexakisphosphate.
    Wilcox RA, Whitham EM, Liu C, Potter BV, Nahorski SR.
    FEBS Lett; 1993 Dec 27; 336(2):267-71. PubMed ID: 8262243
    [Abstract] [Full Text] [Related]

  • 9. Molecular recognition at the myo-inositol 1,4,5-trisphosphate receptor. 3-position substituted myo-inositol 1,4,5-trisphosphate analogues reveal the binding and Ca2+ release requirements for high affinity interaction with the myo-inositol 1,4,5-trisphosphate receptor.
    Wilcox RA, Challiss RA, Traynor JR, Fauq AH, Ognayanov VI, Kozikowski AP, Nahorski SR.
    J Biol Chem; 1994 Oct 28; 269(43):26815-21. PubMed ID: 7929418
    [Abstract] [Full Text] [Related]

  • 10. Acyclophostin: a ribose-modified analog of adenophostin A with high affinity for inositol 1,4,5-trisphosphate receptors and pH-dependent efficacy.
    Beecroft MD, Marchant JS, Riley AM, Van Straten NC, Van der Marel GA, Van Boom JH, Potter BV, Taylor CW.
    Mol Pharmacol; 1999 Jan 28; 55(1):109-17. PubMed ID: 9882704
    [Abstract] [Full Text] [Related]

  • 11. Ca2(+)-mobilising properties of synthetic fluoro-analogues of myo-inositol 1,4,5-trisphosphate and their interaction with myo-inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase.
    Safrany ST, Sawyer D, Wojcikiewicz RJ, Nahorski SR, Potter BV.
    FEBS Lett; 1990 Dec 10; 276(1-2):91-4. PubMed ID: 2176165
    [Abstract] [Full Text] [Related]

  • 12. Synthetic phosphorothioate-containing analogues of inositol 1,4,5-trisphosphate mobilize intracellular Ca2+ stores and interact differentially with inositol 1,4,5-trisphosphate 5-phosphatase and 3-kinase.
    Safrany ST, Wojcikiewicz RJ, Strupish J, McBain J, Cooke AM, Potter BV, Nahorski SR.
    Mol Pharmacol; 1991 Jun 10; 39(6):754-61. PubMed ID: 1646949
    [Abstract] [Full Text] [Related]

  • 13. Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6 -trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors.
    Murphy CT, Bullock AJ, Lindley CJ, Mills SJ, Riley AM, Potter BV, Westwick J.
    Mol Pharmacol; 1996 Nov 10; 50(5):1223-30. PubMed ID: 8913354
    [Abstract] [Full Text] [Related]

  • 14. Use of phosphorofluoridate analogues of D-myo-inositol 1,4,5-trisphosphate to assess the involvement of ionic interactions in its recognition by the receptor and metabolising enzymes.
    Yoshimura K, Watanabe Y, Erneux C, Hirata M.
    Cell Signal; 1999 Feb 10; 11(2):117-25. PubMed ID: 10048789
    [Abstract] [Full Text] [Related]

  • 15. Design of potent and selective inhibitors of myo-inositol 1,4,5-trisphosphate 5-phosphatase.
    Safrany ST, Mills SJ, Liu C, Lampe D, Noble NJ, Nahorski SR, Potter BV.
    Biochemistry; 1994 Sep 06; 33(35):10763-9. PubMed ID: 8075077
    [Abstract] [Full Text] [Related]

  • 16. Adenophostins, newly discovered metabolites of Penicillium brevicompactum, act as potent agonists of the inositol 1,4,5-trisphosphate receptor.
    Takahashi M, Tanzawa K, Takahashi S.
    J Biol Chem; 1994 Jan 07; 269(1):369-72. PubMed ID: 8276820
    [Abstract] [Full Text] [Related]

  • 17. DL-myo-inositol 1,2,4,5-tetrakisphosphate, a potent analog of D-myo-inositol 1,4,5-trisphosphate.
    Hirata M, Narumoto N, Watanabe Y, Kanematsu T, Koga T, Ozaki S.
    Mol Pharmacol; 1994 Feb 07; 45(2):271-6. PubMed ID: 8114676
    [Abstract] [Full Text] [Related]

  • 18. 2-Hydroxyethyl alpha-D-glucopyranoside 2,3',4'-trisphosphate: a novel metabolically resistant adenophostin A and myo-inositol 1,4,5-trisphosphate analogue potently interacts with the myo-inositol 1,4,5-trisphosphate receptor.
    Wilcox RA, Erneux C, Primrose WU, Gigg R, Nahorski SR.
    Biochem Soc Trans; 1995 Aug 07; 23(3):420S. PubMed ID: 8566308
    [No Abstract] [Full Text] [Related]

  • 19. The novel Ins(1,4,5)P3 analogue 3-amino-3-deoxy-Ins(1,4,5)P3: a pH-dependent Ins(1,4,5)P3 receptor partial agonist in SH-SY5Y neuroblastoma cells.
    Kozikowski AP, Fauq AH, Wilcox RA, Challiss RA, Nahorski SR.
    J Med Chem; 1994 Mar 18; 37(6):868-72. PubMed ID: 8145238
    [Abstract] [Full Text] [Related]

  • 20. Synthetic D- and L-enantiomers of 2,2-difluoro-2-deoxy-myo-inositol 1,4,5-trisphosphate interact differently with myo-inositol 1,4,5-trisphosphate binding proteins: identification of a potent small molecule 3-kinase inhibitor.
    Safrany ST, Sawyer DA, Nahorski SR, Potter BV.
    Chirality; 1992 Mar 18; 4(7):415-22. PubMed ID: 1334423
    [Abstract] [Full Text] [Related]

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