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429 related items for PubMed ID: 7621249
1. Transfection of a nonactive site mutant murine DHFR cDNA (the tryptophan 15 mutant) into Chinese hamster ovary and mouse marrow progenitor cells imparts MTX resistance in vitro. Banerjee D, Zhao SC, Tong Y, Steinherz J, Gritsman K, Bertino JR. Cancer Gene Ther; 1994 Sep; 1(3):181-4. PubMed ID: 7621249 [Abstract] [Full Text] [Related]
2. Comparison of methotrexate resistance conferred by a mutated dihydrofolate reductase (DHFR) cDNA in two different retroviral vectors. Takebe N, Nakahara S, Zhao SC, Adhikari D, Ural AU, Iwamoto M, Banerjee D, Bertino JR. Cancer Gene Ther; 2000 Jun; 7(6):910-9. PubMed ID: 10880023 [Abstract] [Full Text] [Related]
3. Transfection with a cDNA encoding a Ser31 or Ser34 mutant human dihydrofolate reductase into Chinese hamster ovary and mouse marrow progenitor cells confers methotrexate resistance. Banerjee D, Schweitzer BI, Volkenandt M, Li MX, Waltham M, Mineishi S, Zhao SC, Bertino JR. Gene; 1994 Feb 25; 139(2):269-74. PubMed ID: 8112617 [Abstract] [Full Text] [Related]
4. Selection for methotrexate resistance in mammalian cells bearing a Drosophila dihydrofolate reductase transgene: Methotrexate resistance in transgenic mammalian cells. Affleck JG, Nowickyj SM, Walker VK. Cell Biol Toxicol; 2010 Apr 25; 26(2):117-26. PubMed ID: 19337845 [Abstract] [Full Text] [Related]
5. [Double-mutant dihydrofolate reductase gene transfection into bone marrow cells protects mice from chemotherapy]. Gao HD, Lu P, Lu Y, Pang K, Xu HM, Wang SB, Chen JQ, Zhao SC. Zhonghua Zhong Liu Za Zhi; 2006 Aug 25; 28(8):583-5. PubMed ID: 17236551 [Abstract] [Full Text] [Related]
6. Selective expression of methotrexate-resistant dihydrofolate reductase (DHFR) activity in mice transduced with DHFR retrovirus and administered methotrexate. Vinh DB, McIvor RS. J Pharmacol Exp Ther; 1993 Nov 25; 267(2):989-96. PubMed ID: 8246174 [Abstract] [Full Text] [Related]
7. Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene. Takebe N, Zhao SC, Adhikari D, Mineishi S, Sadelain M, Hilton J, Colvin M, Banerjee D, Bertino JR. Mol Ther; 2001 Jan 25; 3(1):88-96. PubMed ID: 11162315 [Abstract] [Full Text] [Related]
8. [Mice transduced with double-mutant dihydrofolate reductase-cytidine deaminase fusion gene attained protection from high dose chemotherapy]. Lu P, Lu Y, Pang K, Wang SB, Chen JQ, Xu HM, Wang JK, Zhao SC. Zhonghua Wai Ke Za Zhi; 2005 Aug 01; 43(15):998-1001. PubMed ID: 16194358 [Abstract] [Full Text] [Related]
9. A novel RNA silencing vector to improve antigen expression and stability in Chinese hamster ovary cells. Hong WW, Wu SC. Vaccine; 2007 May 16; 25(20):4103-11. PubMed ID: 17428585 [Abstract] [Full Text] [Related]
10. Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate. James RI, May C, Vagt MD, Studebaker R, McIvor RS. Exp Hematol; 1997 Nov 16; 25(12):1286-95. PubMed ID: 9357973 [Abstract] [Full Text] [Related]
11. Long-term protection of recipient mice from lethal doses of methotrexate by marrow infected with a double-copy vector retrovirus containing a mutant dihydrofolate reductase. Zhao SC, Li MX, Banerjee D, Schweitzer BI, Mineishi S, Gilboa E, Bertino JR. Cancer Gene Ther; 1994 Mar 16; 1(1):27-33. PubMed ID: 7621235 [Abstract] [Full Text] [Related]
12. Regulation of dihydrofolate reductase in human breast cancer cells and in mutant hamster cells transfected with a human dihydrofolate reductase minigene. Cowan KH, Goldsmith ME, Ricciardone MD, Levine R, Rubalcaba E, Jolivet J. Mol Pharmacol; 1986 Jul 16; 30(1):69-76. PubMed ID: 3724746 [Abstract] [Full Text] [Related]
13. Overexpression of human prothrombin in permanent cell lines using a dominant selection/amplification fusion marker. Herlitschka SE, Falkner FG, Schlokat U, Dorner F. Protein Expr Purif; 1996 Nov 16; 8(3):358-64. PubMed ID: 8936598 [Abstract] [Full Text] [Related]
14. Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene. Capiaux GM, Budak-Alpdogan T, Alpdogan O, Bornmann W, Takebe N, Banerjee D, Maley F, Bertino JR. Cancer Gene Ther; 2004 Dec 16; 11(12):767-73. PubMed ID: 15359285 [Abstract] [Full Text] [Related]
15. Increasing methotrexate resistance by combination of active-site mutations in human dihydrofolate reductase. Volpato JP, Fossati E, Pelletier JN. J Mol Biol; 2007 Oct 26; 373(3):599-611. PubMed ID: 17868689 [Abstract] [Full Text] [Related]
16. [Expression of human-mouse chimeric antibody ch-BD1 and its affinity to human bladder cancer in vitro and in vivo]. Bai Y, Yu LZ, Lü YQ, Ai JK, Zhou LJ, Zhang CL, Wang Y. Zhonghua Yi Xue Za Zhi; 2003 Feb 25; 83(4):333-7. PubMed ID: 12812655 [Abstract] [Full Text] [Related]
17. Short hairpin RNA targeted to dihydrofolate reductase enhances the immunoglobulin G expression in gene-amplified stable Chinese hamster ovary cells. Wu SC, Hong WW, Liu JH. Vaccine; 2008 Sep 08; 26(38):4969-74. PubMed ID: 18602963 [Abstract] [Full Text] [Related]
18. Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene. Takebe N, Xu LC, MacKenzie KL, Bertino JR, Moore MA. Cancer Gene Ther; 2002 Mar 08; 9(3):308-20. PubMed ID: 11896448 [Abstract] [Full Text] [Related]
19. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application. McIvor RS. Bone Marrow Transplant; 1996 Dec 08; 18 Suppl 3():S50-4. PubMed ID: 8971409 [Abstract] [Full Text] [Related]
20. Co-expression and amplification of dihydrofolate reductase cDNA and the Escherichia coli XGPRT gene in Chinese hamster ovary cells. Ringold G, Dieckmann B, Lee F. J Mol Appl Genet; 1981 Dec 08; 1(3):165-75. PubMed ID: 6180118 [Abstract] [Full Text] [Related] Page: [Next] [New Search]