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Journal Abstract Search

349 related items for PubMed ID: 7627962

  • 1. 5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression.
    Schwartz EL, Baptiste N, Megati S, Wadler S, Otter BA.
    Cancer Res; 1995 Aug 15; 55(16):3543-50. PubMed ID: 7627962
    [Abstract] [Full Text] [Related]

  • 2. Potentiation of the antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase.
    Schwartz EL, Baptiste N, O'Connor CJ, Wadler S, Otter BA.
    Cancer Res; 1994 Mar 15; 54(6):1472-8. PubMed ID: 8137250
    [Abstract] [Full Text] [Related]

  • 3. Combination of thymidine phosphorylase gene transfer and deoxyinosine treatment greatly enhances 5-fluorouracil antitumor activity in vitro and in vivo.
    Ciccolini J, Cuq P, Evrard A, Giacometti S, Pelegrin A, Aubert C, Cano JP, Iliadis A.
    Mol Cancer Ther; 2001 Dec 15; 1(2):133-9. PubMed ID: 12467230
    [Abstract] [Full Text] [Related]

  • 4. Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil.
    Schwartz EL, Baptiste N, Wadler S, Makower D.
    J Biol Chem; 1995 Aug 11; 270(32):19073-7. PubMed ID: 7642571
    [Abstract] [Full Text] [Related]

  • 5. Interferon induces thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in vivo.
    Makower D, Wadler S, Haynes H, Schwartz EL.
    Clin Cancer Res; 1997 Jun 11; 3(6):923-9. PubMed ID: 9815767
    [Abstract] [Full Text] [Related]

  • 6. Induction of thymidine phosphorylase by interferon and taxanes occurs only in human cancer cells with low thymidine phosphorylase activity.
    Fukushima M, Okabe H, Takechi T, Ichikawa W, Hirayama R.
    Cancer Lett; 2002 Dec 10; 187(1-2):103-10. PubMed ID: 12359357
    [Abstract] [Full Text] [Related]

  • 7. Enhanced antitumor activity of 5-fluorouracil in combination with 2'-deoxyinosine in human colorectal cell lines and human colon tumor xenografts.
    Ciccolini J, Peillard L, Evrard A, Cuq P, Aubert C, Pelegrin A, Formento P, Milano G, Catalin J.
    Clin Cancer Res; 2000 Apr 10; 6(4):1529-35. PubMed ID: 10778986
    [Abstract] [Full Text] [Related]

  • 8. Stimulation of 5-fluorouracil metabolic activation by interferon-alpha in human colon carcinoma cells.
    Schwartz EL, Hoffman M, O'Connor CJ, Wadler S.
    Biochem Biophys Res Commun; 1992 Feb 14; 182(3):1232-9. PubMed ID: 1540167
    [Abstract] [Full Text] [Related]

  • 9. Interferon-alpha 2a up-regulated thymidine phosphorylase and enhanced antitumor effect of capecitabine on hepatocellular carcinoma in nude mice.
    Xiao YS, Tang ZY, Fan J, Zhou J, Wu ZQ, Sun QM, Xue Q, Zhao Y, Liu YK, Ye SL.
    J Cancer Res Clin Oncol; 2004 Sep 14; 130(9):546-50. PubMed ID: 15071737
    [Abstract] [Full Text] [Related]

  • 10. High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil.
    Metzger R, Danenberg K, Leichman CG, Salonga D, Schwartz EL, Wadler S, Lenz HJ, Groshen S, Leichman L, Danenberg PV.
    Clin Cancer Res; 1998 Oct 14; 4(10):2371-6. PubMed ID: 9796967
    [Abstract] [Full Text] [Related]

  • 11. [Influence on 5-fluorouracil metabolism by combination of interferon-alpha and 5-fluorouracil against human hepatocellular carcinoma xenografts].
    Jin CD, Yamamoto T, Nakamura M, Arai I, Kishin R, Xing X, Nagano H, Dono K, Umeshita K, Nakamori S, Sakon M, Monden M.
    Gan To Kagaku Ryoho; 2004 Oct 14; 31(10):1511-5. PubMed ID: 15508442
    [Abstract] [Full Text] [Related]

  • 12. [Interferon alpha enhances the sensitivity of SMMC-7721 hepatocellular carcinoma cells to 5'-deoxy-5-fluorouridine related to up-regulation of thymidine phosphorylase].
    Xiao YS, Zhou J, Fan J, Zhao Y, Sun RX, Liu YK, Ye SL, Tang ZY.
    Zhonghua Yi Xue Za Zhi; 2007 Aug 14; 87(30):2098-100. PubMed ID: 17988526
    [Abstract] [Full Text] [Related]

  • 13. Recombinant human interferon alpha-2a increases 5-fluorouracil efficacy by elevating fluorouridine concentration in tumor tissue.
    Kase S, Kubota T, Watanabe M, Teramoto T, Kitajima M, Hoffman RM.
    Anticancer Res; 1994 Aug 14; 14(3A):1155-9. PubMed ID: 8074466
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  • 15. [Up-regulation of thymidine phosphorylase and anti-angiogenesis by interferon alpha in human hepatocellular carcinoma cell line and xenograft].
    Xiao YS, Zhou J, Tang ZY, Fan J, Wu ZQ, Liu YK, Ye SL, Shen ZZ, Xue Q, Zhao Y.
    Zhonghua Yi Xue Za Zhi; 2005 Nov 30; 85(45):3205-9. PubMed ID: 16405841
    [Abstract] [Full Text] [Related]

  • 16. Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells.
    Ren Q, Van Groeningen CJ, Hardcastle A, Aherne GW, Geoffroy F, Allegra CJ, Johnston PG, Grem JL.
    Oncol Res; 1997 Nov 30; 9(2):77-88. PubMed ID: 9167189
    [Abstract] [Full Text] [Related]

  • 17. Induction of thymidine phosphorylase expression by Taxol does not enhance Furtulon sensitivity in a cisplatin-resistant human ovarian carcinoma cell line.
    Hata K, Osaki M, Kanasaki H, Nakayama K, Fujiwaki R, Ito H, Miyazaki K.
    Anticancer Res; 2003 Nov 30; 23(2B):1525-31. PubMed ID: 12820419
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  • 19. Interferon beta increases antitumor activity of 5-fluorouracil against human colon carcinoma cells in vitro and in vivo.
    Kase S, Kubota T, Watanabe M, Furukawa T, Tanino H, Ishibiki K, Teramoto T, Kitajima M.
    Anticancer Res; 1993 Nov 30; 13(2):369-73. PubMed ID: 8517649
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