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217 related items for PubMed ID: 7634397

  • 1. Intestinal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats: Sex difference, inducibility and inhibition by phenethylisothiocyanate.
    Schulze J, Malone A, Richter E.
    Carcinogenesis; 1995 Aug; 16(8):1733-40. PubMed ID: 7634397
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by hamster, mouse and rat intestine: relevance of species differences.
    Schulze J, Schläger W, Wünsch R, Richter E.
    Carcinogenesis; 1996 May; 17(5):1093-9. PubMed ID: 8640918
    [Abstract] [Full Text] [Related]

  • 3. Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.
    Doerr-O'Rourke K, Trushin N, Hecht SS, Stoner GD.
    Carcinogenesis; 1991 Jun; 12(6):1029-34. PubMed ID: 2044181
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  • 4. The profile of urinary metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats is determined by its pulmonary metabolism.
    Schneider T, Frei E, Wiessler M.
    Chem Biol Interact; 1999 Apr 15; 118(3):247-66. PubMed ID: 10362230
    [Abstract] [Full Text] [Related]

  • 5. Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Carmella SG, Borukhova A, Akerkar SA, Hecht SS.
    Cancer Epidemiol Biomarkers Prev; 1997 Feb 15; 6(2):113-20. PubMed ID: 9037562
    [Abstract] [Full Text] [Related]

  • 6. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E, Engl J, Friesenegger S, Tricker AR.
    Chem Res Toxicol; 2009 Jun 15; 22(6):1008-17. PubMed ID: 19408892
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  • 7. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
    Schrader E, Hirsch-Ernst KI, Richter E, Foth H.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar 15; 357(3):336-43. PubMed ID: 9550307
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  • 10. Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Staretz ME, Koenig LA, Hecht SS.
    Carcinogenesis; 1997 Sep 15; 18(9):1715-22. PubMed ID: 9328166
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  • 11. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
    Smith TJ, Guo ZY, Thomas PE, Chung FL, Morse MA, Elkind K, Yang CS.
    Cancer Res; 1990 Nov 01; 50(21):6817-22. PubMed ID: 2208146
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  • 12. Effects of phenobarbital and 3-methylcholanthrene induction on the formation of three glucuronide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, NNK.
    Murphy SE, Nunes MG, Hatala MA.
    Chem Biol Interact; 1997 Mar 14; 103(3):153-66. PubMed ID: 9134006
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  • 13. Use of precision-cut tissue slices in organ culture to study metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by hamster lung, liver and kidney.
    Richter E, Friesenegger S, Engl J, Tricker AR.
    Toxicology; 2000 Apr 03; 144(1-3):83-91. PubMed ID: 10781874
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  • 14. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
    Guo Z, Smith TJ, Thomas PE, Yang CS.
    Arch Biochem Biophys; 1992 Oct 03; 298(1):279-86. PubMed ID: 1524438
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  • 15. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human kidney epithelial cells transfected with rat CYP2B1 cDNA.
    Lacroix D, Desrochers M, Castonguay A, Anderson A.
    Carcinogenesis; 1993 Aug 03; 14(8):1639-42. PubMed ID: 8353848
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  • 17. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P, Kalscheuer S, Hochalter JB, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2008 Jul 03; 21(7):1468-76. PubMed ID: 18570389
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  • 18. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
    Prokopczyk B, Trushin N, Leszczynska J, Waggoner SE, El-Bayoumy K.
    Carcinogenesis; 2001 Jan 03; 22(1):107-14. PubMed ID: 11159748
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  • 19. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
    Smith TJ, Guo Z, Guengerich FP, Yang CS.
    Carcinogenesis; 1996 Apr 03; 17(4):809-13. PubMed ID: 8625495
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  • 20. Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Zhang S, Wang M, Villalta PW, Lindgren BR, Upadhyaya P, Lao Y, Hecht SS.
    Chem Res Toxicol; 2009 May 03; 22(5):926-36. PubMed ID: 19358518
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