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207 related items for PubMed ID: 7662121

  • 1. Differential mutagenicity and cytotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol and (+/-)-anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide in genetically engineered human fibroblasts.
    Quan T, Reiners JJ, Culp SJ, Richter P, States JC.
    Mol Carcinog; 1995 Feb; 12(2):91-102. PubMed ID: 7662121
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  • 2. Expression of human cytochrome P450 1A1 in DNA repair deficient and proficient human fibroblasts stably transformed with an inducible expression vector.
    States JC, Quan T, Hines RN, Novak RF, Runge-Morris M.
    Carcinogenesis; 1993 Aug; 14(8):1643-9. PubMed ID: 8353849
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  • 3. Cytotoxicity and genotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol in CYP1A1-expressing human fibroblasts quantitatively correlate with CYP1A1 expression level.
    Quan T, Reiners JJ, Bell AO, Hong N, States JC.
    Carcinogenesis; 1994 Sep; 15(9):1827-32. PubMed ID: 7923575
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  • 4. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME, Kabler SL, Fleming MH, Ravoori S, Gupta RC, Doehmer J, Morrow CS, Townsend AJ.
    Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195
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  • 5. The role of the Ah receptor and p38 in benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced apoptosis.
    Chen S, Nguyen N, Tamura K, Karin M, Tukey RH.
    J Biol Chem; 2003 May 23; 278(21):19526-33. PubMed ID: 12637498
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  • 6. Preferential DNA damage in the p53 gene by benzo[a]pyrene metabolites in cytochrome P4501A1-expressing xeroderma pigmentosum group A cells.
    Quan T, States JC.
    Mol Carcinog; 1996 May 23; 16(1):32-43. PubMed ID: 8634092
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  • 7. In vivo formation and persistence of DNA adducts in mouse and rat skin exposed to (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene and (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
    Rojas M, Alexandrov K.
    Carcinogenesis; 1986 Sep 23; 7(9):1553-60. PubMed ID: 3091285
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  • 9. Differences in the rate of DNA adduct removal and the efficiency of mutagenesis for two benzo[a]pyrene diol epoxides in CHO cells.
    MacLeod MC, Daylong A, Adair G, Humphrey RM.
    Mutat Res; 1991 Dec 23; 261(4):267-79. PubMed ID: 1722282
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  • 11. Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts.
    Chen RH, Maher VM, Brouwer J, van de Putte P, McCormick JJ.
    Proc Natl Acad Sci U S A; 1992 Jun 15; 89(12):5413-7. PubMed ID: 1608950
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  • 12. Metabolic activation of racemic and enantiomeric trans-8, 9-dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (dibenzo[def,p]chrysene) to dibenzo[a,l]pyrene-bis-dihydrodiols by induced rat liver microsomes and a recombinant human P450 1A1 system: the role of the K-region-derived metabolic intermediates in the formation of dibenzo[a,l]pyrene-DNA adducts.
    Nesnow S, Davis C, Padgett W, George M, Lambert G, Meyers F, Allison J, Adams L, King LC.
    Chem Res Toxicol; 1998 Dec 15; 11(12):1596-607. PubMed ID: 9860506
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  • 14. Trans- and cis-DNA adduct concentration in epidermis from mouse and rat skin treated ex vivo with benzo[a]pyrene diol epoxide and its corresponding chlorohydrin.
    Vock EH, Wolfe AR, Meehan T.
    Mutat Res; 2001 Jul 01; 478(1-2):199-206. PubMed ID: 11406185
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  • 17. Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra.
    Wei D, Maher VM, McCormick JJ.
    Proc Natl Acad Sci U S A; 1995 Mar 14; 92(6):2204-8. PubMed ID: 7892248
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