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155 related items for PubMed ID: 7676453

  • 1. Biotransformation and hepatotoxicity of HCFC-123 in the guinea pig: potentiation of hepatic injury by prior glutathione depletion.
    Lind RC, Gandolfi AJ, Hall PD.
    Toxicol Appl Pharmacol; 1995 Sep; 134(1):175-81. PubMed ID: 7676453
    [Abstract] [Full Text] [Related]

  • 2. Potentiation of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123)-induced liver toxicity by ethanol in guinea-pigs.
    Hoet P, Buchet JP, Sempoux C, Haufroid V, Rahier J, Lison D.
    Arch Toxicol; 2002 Dec; 76(12):707-14. PubMed ID: 12451447
    [Abstract] [Full Text] [Related]

  • 3. Investigations on the liver toxicity of a blend of HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane) and HCFC-124 (2-chloro-1,1,1,2-tetrafluoroethane) in guinea-pigs.
    Hoet P, Buchet JP, Sempoux C, Nomiyama T, Rahier J, Lison D.
    Arch Toxicol; 2001 Jul; 75(5):274-83. PubMed ID: 11548120
    [Abstract] [Full Text] [Related]

  • 4. Hepatotoxicity in guinea pigs following acute inhalation exposure to 1,1-dichloro-2,2,2-trifluoroethane.
    Marit GB, Dodd DE, George ME, Vinegar A.
    Toxicol Pathol; 1994 Jul; 22(4):404-14. PubMed ID: 7817129
    [Abstract] [Full Text] [Related]

  • 5. A model for fatal halothane hepatitis in the guinea pig.
    Lind RC, Gandolfi AJ, Hall PM.
    Anesthesiology; 1994 Aug; 81(2):478-87. PubMed ID: 8053598
    [Abstract] [Full Text] [Related]

  • 6. Metabolism of 1,1-dichloro-2,2,2-trifluoroethane in rats.
    Urban G, Dekant W.
    Xenobiotica; 1994 Sep; 24(9):881-92. PubMed ID: 7810170
    [Abstract] [Full Text] [Related]

  • 7. Glutathione depletion enhances subanesthetic halothane hepatotoxicity in guinea pigs.
    Lind RC, Gandolfi AJ, Hall PM.
    Anesthesiology; 1992 Oct; 77(4):721-7. PubMed ID: 1416169
    [Abstract] [Full Text] [Related]

  • 8. The role of cytochrome P450 2E1 in the species-dependent biotransformation of 1,2-dichloro-1,1,2-trifluoroethane in rats and mice.
    Dekant W, Assmann M, Urban G.
    Toxicol Appl Pharmacol; 1995 Dec; 135(2):200-7. PubMed ID: 8545828
    [Abstract] [Full Text] [Related]

  • 9. Late dimethyl sulfoxide administration provides a protective action against chemically induced injury in both the liver and the kidney.
    Lind RC, Gandolfi AJ.
    Toxicol Appl Pharmacol; 1997 Jan; 142(1):201-7. PubMed ID: 9007050
    [Abstract] [Full Text] [Related]

  • 10. Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes.
    Ferrara R, Tolando R, King LJ, Manno M.
    Toxicol Appl Pharmacol; 1997 Apr; 143(2):420-8. PubMed ID: 9144458
    [Abstract] [Full Text] [Related]

  • 11. Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane.
    Bortolato S, Zanovello A, Rugge M, Brotto M, Marini S, Gervasi PG, Manno M.
    Toxicol Lett; 2003 Sep 15; 144(1):35-47. PubMed ID: 12919722
    [Abstract] [Full Text] [Related]

  • 12. Covalent binding of oxidative biotransformation intermediates is associated with halothane hepatotoxicity in guinea pigs.
    Lind RC, Gandolfi AJ, Hall PD.
    Anesthesiology; 1990 Dec 15; 73(6):1208-13. PubMed ID: 2248397
    [Abstract] [Full Text] [Related]

  • 13. Pentahaloethane-based chlorofluorocarbon substitutes and halothane: correlation of in vivo hepatic protein trifluoroacetylation and urinary trifluoroacetic acid excretion with calculated enthalpies of activation.
    Harris JW, Jones JP, Martin JL, LaRosa AC, Olson MJ, Pohl LR, Anders MW.
    Chem Res Toxicol; 1992 Dec 15; 5(5):720-5. PubMed ID: 1446014
    [Abstract] [Full Text] [Related]

  • 14. Phenylpropanolamine potentiation of acetaminophen-induced hepatotoxicity: evidence for a glutathione-dependent mechanism.
    James RC, Harbison RD, Roberts SM.
    Toxicol Appl Pharmacol; 1993 Feb 15; 118(2):159-68. PubMed ID: 8382844
    [Abstract] [Full Text] [Related]

  • 15. Halothane-induced liver injury as a consequence of enhanced microsomal lipid peroxidation in guinea pigs.
    Akita S, Morio M, Kawahara M, Takeshita T, Fujii K, Yamamoto M.
    Res Commun Chem Pathol Pharmacol; 1988 Aug 15; 61(2):227-43. PubMed ID: 3187193
    [Abstract] [Full Text] [Related]

  • 16. Metabolism of 1,2-dichloro-1-fluoroethane and 1-fluoro-1,2,2-trichloroethane: electronic factors govern the regioselectivity of cytochrome P450-dependent oxidation.
    Yin H, Anders MW, Jones JP.
    Chem Res Toxicol; 1996 Aug 15; 9(1):50-7. PubMed ID: 8924616
    [Abstract] [Full Text] [Related]

  • 17. Gas-uptake pharmacokinetics and biotransformation of 1,1-dichloro-1-fluoroethane (HCFC-141b).
    Loizou GD, Anders MW.
    Drug Metab Dispos; 1993 Aug 15; 21(4):634-9. PubMed ID: 8104122
    [Abstract] [Full Text] [Related]

  • 18. Effects of acute glutathione depletion induced by L-buthionine-(S,R)-sulfoximine on rat liver glucose-6-phosphatase activity.
    Santori G, Domenicotti C, Bellocchio A, Pronzato MA, Marinari UM, Poli G, Cottalasso D.
    Res Commun Mol Pathol Pharmacol; 1997 Nov 15; 98(2):165-78. PubMed ID: 9467825
    [Abstract] [Full Text] [Related]

  • 19. Covalent binding of oxidative biotransformation reactive intermediates to protein influences halothane-associated hepatotoxicity in guinea pigs.
    Lind RC, Gandolfi AJ.
    Adv Exp Med Biol; 1991 Nov 15; 283():763-6. PubMed ID: 2069053
    [Abstract] [Full Text] [Related]

  • 20. Subanesthetic halothane is hepatotoxic in the guinea pig.
    Lind RC, Gandolfi AJ, Hall PD.
    Anesth Analg; 1992 Apr 15; 74(4):559-63. PubMed ID: 1554123
    [Abstract] [Full Text] [Related]

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