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Journal Abstract Search

201 related items for PubMed ID: 7682615

  • 1. 2-Aminochromones block human platelet aggregation by inhibiting cyclic AMP-dependent phosphodiesterase leading to reduced platelet phospholipase C activity.
    Benjamin CW, Lin AH, Morris J, Wishka DG, Gorman RR.
    J Pharmacol Exp Ther; 1993 Apr; 265(1):457-62. PubMed ID: 7682615
    [Abstract] [Full Text] [Related]

  • 2. 7-Bromo-1,5-dihydro-3,6-dimethylimidazo[2,1-b]quinazolin-2(3H)- one (Ro 15-2041), a potent antithrombotic agent that selectively inhibits platelet cyclic AMP-phosphodiesterase.
    Muggli R, Tschopp TB, Mittelholzer E, Baumgartner HR.
    J Pharmacol Exp Ther; 1985 Oct; 235(1):212-9. PubMed ID: 2995647
    [Abstract] [Full Text] [Related]

  • 3. A new insight of anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP phosphodiesterase.
    Liu FC, Liao CH, Chang YW, Liou JT, Day YJ.
    Biochem Pharmacol; 2009 Apr 15; 77(8):1364-73. PubMed ID: 19426675
    [Abstract] [Full Text] [Related]

  • 4. Mechanisms of antiplatelet activity of PC-09, a newly synthesized pyridazinone derivative.
    Cherng SC, Huang WH, Shiau CY, Lee AR, Chou TC.
    Eur J Pharmacol; 2006 Feb 17; 532(1-2):32-7. PubMed ID: 16457809
    [Abstract] [Full Text] [Related]

  • 5. Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.
    Abbott BM, Thompson PE.
    Bioorg Med Chem Lett; 2006 Feb 15; 16(4):969-73. PubMed ID: 16290931
    [Abstract] [Full Text] [Related]

  • 6. Control of platelet activation by cyclic AMP turnover and cyclic nucleotide phosphodiesterase type-3.
    Feijge MA, Ansink K, Vanschoonbeek K, Heemskerk JW.
    Biochem Pharmacol; 2004 Apr 15; 67(8):1559-67. PubMed ID: 15041473
    [Abstract] [Full Text] [Related]

  • 7. Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases.
    Manns JM, Brenna KJ, Colman RW, Sheth SB.
    Thromb Haemost; 2002 May 15; 87(5):873-9. PubMed ID: 12038792
    [Abstract] [Full Text] [Related]

  • 8. Mechanisms of antiplatelet and antithrombotic activity of midazolam in in vitro and in vivo studies.
    Hsiao G, Shen MY, Chou DS, Chang Y, Lee LW, Lin CH, Sheu JR.
    Eur J Pharmacol; 2004 Mar 08; 487(1-3):159-66. PubMed ID: 15033388
    [Abstract] [Full Text] [Related]

  • 9. alpha-Naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation.
    Hsiao G, Chang CY, Shen MY, Chou DS, Tzeng SH, Chen TF, Sheu JR.
    J Agric Food Chem; 2005 Jun 29; 53(13):5179-86. PubMed ID: 15969494
    [Abstract] [Full Text] [Related]

  • 10. Synergistic antiplatelet effect of ridogrel, a combined thromboxane receptor antagonist and thromboxane synthase inhibitor, and UDCG-212, a cAMP-phosphodiesterase inhibitor.
    Hoet B, Arnout J, Deckmyn H, Vermylen J.
    Thromb Haemost; 1993 Nov 15; 70(5):822-5. PubMed ID: 8128441
    [Abstract] [Full Text] [Related]

  • 11. Regulation of protease-activated receptor (PAR) 1 and PAR4 signaling in human platelets by compartmentalized cyclic nucleotide actions.
    Bilodeau ML, Hamm HE.
    J Pharmacol Exp Ther; 2007 Aug 15; 322(2):778-88. PubMed ID: 17525299
    [Abstract] [Full Text] [Related]

  • 12. Inhibitory effect of GBH on platelet aggregation through inhibition of intracellular Ca2+ mobilization in activated human platelets.
    Park WH, Kim HK, Nam KS, Shon YH, Jeon BH, Moon SK, Kim MG, Kim CH.
    Life Sci; 2004 Nov 05; 75(25):3063-76. PubMed ID: 15474558
    [Abstract] [Full Text] [Related]

  • 13. Octimibate inhibition of platelet aggregation: stimulation of adenylate cyclase through prostacyclin receptor activation.
    Seiler S, Brassard CL, Arnold AJ, Meanwell NA, Fleming JS, Keely SL.
    J Pharmacol Exp Ther; 1990 Dec 05; 255(3):1021-6. PubMed ID: 2175792
    [Abstract] [Full Text] [Related]

  • 14. Effect of cAMP phosphodiesterase inhibitors on ADP-induced shape change, cAMP and nucleoside diphosphokinase activity of rabbit platelets.
    Lam SC, Guccione MA, Packham MA, Mustard JF.
    Thromb Haemost; 1982 Apr 30; 47(2):90-5. PubMed ID: 6285543
    [Abstract] [Full Text] [Related]

  • 15. Model of prostaglandin-regulated cyclic AMP metabolism in intact platelets: examination of time-dependent effects on adenylate cyclase and phosphodiesterase activities.
    Ashby B.
    Mol Pharmacol; 1989 Dec 30; 36(6):866-73. PubMed ID: 2481225
    [Abstract] [Full Text] [Related]

  • 16. Activation of cyclic GMP-binding and cyclic AMP-specific phosphodiesterases of rat platelets by a mechanism involving cyclic AMP-dependent phosphorylation.
    Tremblay J, Lachance B, Hamet P.
    J Cyclic Nucleotide Protein Phosphor Res; 1985 Dec 30; 10(4):397-411. PubMed ID: 2411769
    [Abstract] [Full Text] [Related]

  • 17. Potent antiplatelet activity of sesamol in an in vitro and in vivo model: pivotal roles of cyclic AMP and p38 mitogen-activated protein kinase.
    Chang CC, Lu WJ, Chiang CW, Jayakumar T, Ong ET, Hsiao G, Fong TH, Chou DS, Sheu JR.
    J Nutr Biochem; 2010 Dec 30; 21(12):1214-21. PubMed ID: 20015631
    [Abstract] [Full Text] [Related]

  • 18. Splitomicin suppresses human platelet aggregation via inhibition of cyclic AMP phosphodiesterase and intracellular Ca++ release.
    Liu FC, Liao CH, Chang YW, Liou JT, Day YJ.
    Thromb Res; 2009 Jun 30; 124(2):199-207. PubMed ID: 19327818
    [Abstract] [Full Text] [Related]

  • 19. Thrombin-stimulated phospholipase C activity is inhibited without visible delay by a rapid increase in the cyclic GMP levels induced by sodium nitroprusside.
    Azula FJ, Alzola ES, Conde M, Trueba M, Macarulla JM, Marino A.
    Mol Pharmacol; 1996 Aug 30; 50(2):367-79. PubMed ID: 8700145
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of platelet aggregation by olive oil phenols via cAMP-phosphodiesterase.
    Dell'Agli M, Maschi O, Galli GV, Fagnani R, Dal Cero E, Caruso D, Bosisio E.
    Br J Nutr; 2008 May 30; 99(5):945-51. PubMed ID: 17927845
    [Abstract] [Full Text] [Related]

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