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PUBMED FOR HANDHELDS

Journal Abstract Search


206 related items for PubMed ID: 7685281

  • 1. Novel hirudin variants from the leech Hirudinaria manillensis. Amino acid sequence, cDNA cloning and genomic organization.
    Scacheri E, Nitti G, Valsasina B, Orsini G, Visco C, Ferrera M, Sawyer RT, Sarmientos P.
    Eur J Biochem; 1993 May 15; 214(1):295-304. PubMed ID: 7685281
    [Abstract] [Full Text] [Related]

  • 2. Probing the structure of hirudin from Hirudinaria manillensis by limited proteolysis. Isolation, characterization and thrombin-inhibitory properties of N-terminal fragments.
    Vindigni A, De Filippis V, Zanotti G, Visco C, Orsini G, Fontana A.
    Eur J Biochem; 1994 Dec 01; 226(2):323-33. PubMed ID: 8001550
    [Abstract] [Full Text] [Related]

  • 3. The complete amino acid sequence of a hirudin variant from the leech Hirudinaria manillensis.
    Electricwala A, Hartwell R, Scawen MD, Atkinson T.
    J Protein Chem; 1993 Jun 01; 12(3):365-70. PubMed ID: 8397794
    [Abstract] [Full Text] [Related]

  • 4. Isolation of thrombin inhibitor from the leech Hirudinaria manillensis.
    Electricwala A, Sawyer RT, Jones CP, Atkinson T.
    Blood Coagul Fibrinolysis; 1991 Feb 01; 2(1):83-9. PubMed ID: 1773002
    [Abstract] [Full Text] [Related]

  • 5. Hirudins of the Asian medicinal leech, Hirudinaria manillensis: same same, but different.
    Lukas P, Wolf R, Rauch BH, Hildebrandt JP, Müller C.
    Parasitol Res; 2019 Jul 01; 118(7):2223-2233. PubMed ID: 31187225
    [Abstract] [Full Text] [Related]

  • 6. Core domain of hirudin from the leech Hirudinaria manillensis: chemical synthesis, purification, and characterization of a Trp3 analog of fragment 1-47.
    De Filippis V, Vindigni A, Altichieri L, Fontana A.
    Biochemistry; 1995 Jul 25; 34(29):9552-64. PubMed ID: 7626625
    [Abstract] [Full Text] [Related]

  • 7. Primary structure and function of novel O-glycosylated hirudins from the leech Hirudinaria manillensis.
    Steiner V, Knecht R, Börnsen KO, Gassmann E, Stone SR, Raschdorf F, Schlaeppi JM, Maschler R.
    Biochemistry; 1992 Mar 03; 31(8):2294-8. PubMed ID: 1540584
    [Abstract] [Full Text] [Related]

  • 8. Molecular dynamic and pharmacological studies on protein-engineered hirudin variants of Hirudinaria manillensis and Hirudo medicinalis.
    Sun Y, Wang B, Pei J, Luo Y, Yuan N, Xiao Z, Wu H, Luo C, Wang J, Wei S, Pei Y, Fu S, Wang D.
    Br J Pharmacol; 2022 Jul 03; 179(14):3740-3753. PubMed ID: 35135035
    [Abstract] [Full Text] [Related]

  • 9. Rapid purification and revised amino-terminal sequence of hirudin: a specific thrombin inhibitor of the bloodsucking leech.
    Mao SJ, Yates MT, Blankenship DT, Cardin AD, Krstenansky JL, Lovenberg W, Jackson RL.
    Anal Biochem; 1987 Mar 03; 161(2):514-8. PubMed ID: 3578808
    [Abstract] [Full Text] [Related]

  • 10. NMR solution structure of a novel hirudin variant HM2, N-terminal 1-47 and N64-->V + G mutant.
    Nicastro G, Baumer L, Bolis G, Tatò M.
    Biopolymers; 1997 Jun 03; 41(7):731-49. PubMed ID: 9128439
    [Abstract] [Full Text] [Related]

  • 11. Cloning and expression of a cDNA coding for the anticoagulant hirudin from the bloodsucking leech, Hirudo medicinalis.
    Harvey RP, Degryse E, Stefani L, Schamber F, Cazenave JP, Courtney M, Tolstoshev P, Lecocq JP.
    Proc Natl Acad Sci U S A; 1986 Feb 03; 83(4):1084-8. PubMed ID: 3513162
    [Abstract] [Full Text] [Related]

  • 12. Structure-function relationships of the C-terminal functional domain of hirudin and its variants.
    Krstenansky JL, Mao SJ.
    Blood Coagul Fibrinolysis; 1991 Feb 03; 2(1):91-6. PubMed ID: 1773003
    [Abstract] [Full Text] [Related]

  • 13. Short tail stories: the hirudin-like factors HLF6 and HLF7 of the Asian medicinal leech, Hirudinaria manillensis.
    Müller C, Eickelmann C, Sponholz D, Hildebrandt JP.
    Parasitol Res; 2021 Nov 03; 120(11):3761-3769. PubMed ID: 34599360
    [Abstract] [Full Text] [Related]

  • 14. Investigation on minor degraded derivatives of the recombinant hirudin variant HM2 from Hirudinaria manillensis isolated by isoelectric focusing in multicompartment electrolyzers.
    Bossi A, Righetti PG, Visco C, Breme U, Mauriello M, Valsasina B, Orsini G, Wenisch E.
    Electrophoresis; 1996 May 03; 17(5):932-7. PubMed ID: 8783019
    [Abstract] [Full Text] [Related]

  • 15. C-terminal proteolytic degradation of recombinant desulfato-hirudin and its mutants in the yeast Saccharomyces cerevisiae.
    Heim J, Takabayashi K, Meyhack B, Märki W, Pohlig G.
    Eur J Biochem; 1994 Dec 01; 226(2):341-53. PubMed ID: 8001551
    [Abstract] [Full Text] [Related]

  • 16. CX-397, a novel recombinant hirudin analog having a hybrid sequence of hirudin variants-1 and -3.
    Komatsu Y, Misawa S, Sukesada A, Ohba Y, Hayashi H.
    Biochem Biophys Res Commun; 1993 Oct 29; 196(2):773-9. PubMed ID: 8240353
    [Abstract] [Full Text] [Related]

  • 17. Incorporation of noncoded amino acids into the N-terminal domain 1-47 of hirudin yields a highly potent and selective thrombin inhibitor.
    De Filippis V, Russo I, Vindigni A, Di Cera E, Salmaso S, Fontana A.
    Protein Sci; 1999 Oct 29; 8(10):2213-7. PubMed ID: 10548068
    [Abstract] [Full Text] [Related]

  • 18. Life without blood: Molecular and functional analysis of hirudins and hirudin-like factors of the Asian non-hematophagous leech Whitmania pigra.
    Müller C, Wang Z, Hamann M, Sponholz D, Hildebrandt JP.
    J Thromb Haemost; 2022 Aug 29; 20(8):1808-1817. PubMed ID: 35587545
    [Abstract] [Full Text] [Related]

  • 19. Expression, purification and characterization of multigram amounts of a recombinant hybrid HV1-HV2 hirudin variant expressed in Saccharomyces cerevisiae.
    Lehman ED, Joyce JG, Bailey FJ, Markus HZ, Schultz LD, Dunwiddie CT, Jacobson MA, Miller WJ.
    Protein Expr Purif; 1993 Jun 29; 4(3):247-55. PubMed ID: 8518563
    [Abstract] [Full Text] [Related]

  • 20. Isolation and purification of novel hirudins from the leech Hirudinaria manillensis by high-performance liquid chromatography.
    Steiner V, Knecht R, Gruetter M, Raschdorf F, Gassmann E, Maschler R.
    J Chromatogr; 1990 Sep 14; 530(2):273-82. PubMed ID: 2079503
    [Abstract] [Full Text] [Related]


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