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171 related items for PubMed ID: 7685584

  • 1. [Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Nishiyama M, Saeki S, Aogi K, Hirabayashi N, Toge T.
    Gan To Kagaku Ryoho; 1993 Jun; 20(8):1037-41. PubMed ID: 7685584
    [Abstract] [Full Text] [Related]

  • 2. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C.
    Saeki S, Nishiyama M, Toge T.
    Hiroshima J Med Sci; 1995 Sep; 44(3):55-63. PubMed ID: 8567314
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D, Gibson NW, Preusch PC, Ross D.
    Cancer Res; 1990 Dec 01; 50(23):7483-9. PubMed ID: 1701346
    [Abstract] [Full Text] [Related]

  • 4. DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines.
    Mikami K, Naito M, Tomida A, Yamada M, Sirakusa T, Tsuruo T.
    Cancer Res; 1996 Jun 15; 56(12):2823-6. PubMed ID: 8665520
    [Abstract] [Full Text] [Related]

  • 5. [DT-diaphorase].
    Mikami K, Shirakusa T, Tsuruo T.
    Gan To Kagaku Ryoho; 1997 Sep 15; 24(11):1606-10. PubMed ID: 9309161
    [Abstract] [Full Text] [Related]

  • 6. Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase.
    Wang X, Doherty GP, Leith MK, Curphey TJ, Begleiter A.
    Br J Cancer; 1999 Jun 15; 80(8):1223-30. PubMed ID: 10376975
    [Abstract] [Full Text] [Related]

  • 7. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD, Horikoshi T, Danenberg KD, Stadlbauer TH, Danenberg PV, Ross D, Gibson NW.
    Cancer Res; 1992 Feb 15; 52(4):797-802. PubMed ID: 1737339
    [Abstract] [Full Text] [Related]

  • 8. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under hypoxia.
    Begleiter A, Robotham E, Leith MK.
    Mol Pharmacol; 1992 Apr 15; 41(4):677-82. PubMed ID: 1373799
    [Abstract] [Full Text] [Related]

  • 9. Tumor-specific synergistic therapy of mitomycin C: modulation of bioreductive activation.
    Sakamoto N, Toge T, Nishiyama M.
    Hiroshima J Med Sci; 1997 Jun 15; 46(2):67-73. PubMed ID: 9232934
    [Abstract] [Full Text] [Related]

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  • 11. Enzymatic and pH modulation of mitomycin C-induced DNA damage in mitomycin C-resistant HCT 116 human colon cancer cells.
    Pan SS, Yu F, Hipsher C.
    Mol Pharmacol; 1993 Jun 15; 43(6):870-7. PubMed ID: 8316219
    [Abstract] [Full Text] [Related]

  • 12. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb 15; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

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  • 14. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under acidic conditions.
    Begleiter A, Leith MK.
    Mol Pharmacol; 1993 Jul 15; 44(1):210-5. PubMed ID: 8341273
    [Abstract] [Full Text] [Related]

  • 15. Expression of DT-diaphorase and cytochrome P450 reductase correlates with mitomycin C activity in human bladder tumors.
    Gan Y, Mo Y, Kalns JE, Lu J, Danenberg K, Danenberg P, Wientjes MG, Au JL.
    Clin Cancer Res; 2001 May 15; 7(5):1313-9. PubMed ID: 11350900
    [Abstract] [Full Text] [Related]

  • 16. Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C.
    Kuehl BL, Buchwald M, Rauth AM.
    Oncol Res; 1993 May 15; 5(6-7):213-21. PubMed ID: 8123941
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D, Gibson NW, Preusch PC, Ross D.
    Cancer Res; 1990 Nov 15; 50(22):7293-300. PubMed ID: 2121335
    [Abstract] [Full Text] [Related]

  • 18. Involvement of activator protein-1 and nuclear factor-kappaB transcription factors in the control of the DT-diaphorase expression induced by mitomycin C treatment.
    Yao KS, Hageboutros A, Ford P, O'Dwyer PJ.
    Mol Pharmacol; 1997 Mar 15; 51(3):422-30. PubMed ID: 9058597
    [Abstract] [Full Text] [Related]

  • 19. Cytotoxic mechanisms of anti-tumour quinones in parental and resistant lymphoblasts.
    Halinska A, Belej T, O'Brien PJ.
    Br J Cancer Suppl; 1996 Jul 15; 27():S23-7. PubMed ID: 8763840
    [Abstract] [Full Text] [Related]

  • 20. [Mechanism of resistance to mitomycin C in a human bladder cancer cell line].
    Xu B, Sun Y, Singh SV.
    Zhonghua Zhong Liu Za Zhi; 1995 Sep 15; 17(5):343-6. PubMed ID: 8697971
    [Abstract] [Full Text] [Related]

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