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317 related items for PubMed ID: 7693331

  • 1. Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns.
    Bizanek R, Chowdary D, Arai H, Kasai M, Hughes CS, Sartorelli AC, Rockwell S, Tomasz M.
    Cancer Res; 1993 Nov 01; 53(21):5127-34. PubMed ID: 7693331
    [Abstract] [Full Text] [Related]

  • 2. Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1989 Jun 15; 49(12):3310-3. PubMed ID: 2470504
    [Abstract] [Full Text] [Related]

  • 3. Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C.
    Palom Y, Belcourt MF, Kumar GS, Arai H, Kasai M, Sartorelli AC, Rockwell S, Tomasz M.
    Oncol Res; 1998 Jun 15; 10(10):509-21. PubMed ID: 10338154
    [Abstract] [Full Text] [Related]

  • 4. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM, Sartorelli AC.
    Cancer Res; 1986 Aug 15; 46(8):3939-44. PubMed ID: 3089583
    [Abstract] [Full Text] [Related]

  • 5. Enzymatic and pH modulation of mitomycin C-induced DNA damage in mitomycin C-resistant HCT 116 human colon cancer cells.
    Pan SS, Yu F, Hipsher C.
    Mol Pharmacol; 1993 Jun 15; 43(6):870-7. PubMed ID: 8316219
    [Abstract] [Full Text] [Related]

  • 6. Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines.
    Kim SY, Rockwell S.
    Oncol Res; 1995 Jun 15; 7(5):39-47. PubMed ID: 8534933
    [Abstract] [Full Text] [Related]

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  • 8. Isolation, identification, and assay of [3H]-porfiromycin adducts of EMT6 mouse mammary tumor cell DNA: effects of hypoxia and dicumarol on adduct patterns.
    Tomasz M, Hughes CS, Chowdary D, Keyes SR, Lipman R, Sartorelli AC, Rockwell S.
    Cancer Commun; 1991 Jul 15; 3(7):213-23. PubMed ID: 1714285
    [Abstract] [Full Text] [Related]

  • 9. Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol.
    Palom Y, Belcourt MF, Tang LQ, Mehta SS, Sartorelli AC, Pritsos CA, Pritsos KL, Rockwell S, Tomasz M.
    Biochem Pharmacol; 2001 Jun 15; 61(12):1517-29. PubMed ID: 11377381
    [Abstract] [Full Text] [Related]

  • 10. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
    Beall HD, Mulcahy RT, Siegel D, Traver RD, Gibson NW, Ross D.
    Cancer Res; 1994 Jun 15; 54(12):3196-201. PubMed ID: 8205540
    [Abstract] [Full Text] [Related]

  • 11. Effect of the superoxide dismutase inhibitor, diethyldithiocarbamate, on the cytotoxicity of mitomycin antibiotics.
    Pritsos CA, Keyes SR, Sartorelli AC.
    Cancer Biochem Biophys; 1989 Oct 15; 10(4):289-98. PubMed ID: 2559790
    [Abstract] [Full Text] [Related]

  • 12. Relative toxicities of DNA cross-links and monoadducts: new insights from studies of decarbamoyl mitomycin C and mitomycin C.
    Palom Y, Suresh Kumar G, Tang LQ, Paz MM, Musser SM, Rockwell S, Tomasz M.
    Chem Res Toxicol; 2002 Nov 15; 15(11):1398-406. PubMed ID: 12437330
    [Abstract] [Full Text] [Related]

  • 13. Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1985 Jan 15; 45(1):213-6. PubMed ID: 2578093
    [Abstract] [Full Text] [Related]

  • 14. Modulation of the cytotoxicity of mitomycin C to EMT6 mouse mammary tumor cells by dicoumarol in vitro.
    Rockwell S, Keyes SR, Sartorelli AC.
    Cancer Res; 1988 Oct 01; 48(19):5471-4. PubMed ID: 2458178
    [Abstract] [Full Text] [Related]

  • 15. A mitomycin-N6-deoxyadenosine adduct isolated from DNA.
    Palom Y, Lipman R, Musser SM, Tomasz M.
    Chem Res Toxicol; 1998 Mar 01; 11(3):203-10. PubMed ID: 9544618
    [Abstract] [Full Text] [Related]

  • 16. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
    Suresh Kumar G, Lipman R, Cummings J, Tomasz M.
    Biochemistry; 1997 Nov 18; 36(46):14128-36. PubMed ID: 9369485
    [Abstract] [Full Text] [Related]

  • 17. Reductive activation of mitomycin C by NADH:cytochrome b5 reductase.
    Hodnick WF, Sartorelli AC.
    Cancer Res; 1993 Oct 15; 53(20):4907-12. PubMed ID: 8402680
    [Abstract] [Full Text] [Related]

  • 18. Effect of pH on DNA alkylation by enzyme-activated mitomycin C and porfiromycin.
    Yu F, Pan SS.
    Mol Pharmacol; 1993 Jun 15; 43(6):863-9. PubMed ID: 8391116
    [Abstract] [Full Text] [Related]

  • 19. pH dependence of mitomycin C-induced cross-linking activity in EMT6 tumor cells.
    Kennedy KA, McGurl JD, Leondaridis L, Alabaster O.
    Cancer Res; 1985 Aug 15; 45(8):3541-7. PubMed ID: 3926302
    [Abstract] [Full Text] [Related]

  • 20. Generation of reactive oxygen radicals through bioactivation of mitomycin antibiotics.
    Pritsos CA, Sartorelli AC.
    Cancer Res; 1986 Jul 15; 46(7):3528-32. PubMed ID: 3011250
    [Abstract] [Full Text] [Related]

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