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149 related items for PubMed ID: 7693661

  • 1. Lovastatin inhibits platelet-derived growth factor (PDGF) stimulation of phosphatidylinositol 3-kinase activity as well as association of p85 subunit to tyrosine-phosphorylated PDGF receptor.
    McGuire TF, Corey SJ, Sebti SM.
    J Biol Chem; 1993 Oct 25; 268(30):22227-30. PubMed ID: 7693661
    [Abstract] [Full Text] [Related]

  • 2. The catalytic subunit of phosphatidylinositol 3-kinase is a substrate for the activated platelet-derived growth factor receptor, but not for middle-T antigen-pp60c-src complexes.
    Roche S, Dhand R, Waterfield MD, Courtneidge SA.
    Biochem J; 1994 Aug 01; 301 ( Pt 3)(Pt 3):703-11. PubMed ID: 7519847
    [Abstract] [Full Text] [Related]

  • 3. Lovastatin disrupts early events in insulin signaling: a potential mechanism of lovastatin's anti-mitogenic activity.
    McGuire TF, Xu XQ, Corey SJ, Romero GG, Sebti SM.
    Biochem Biophys Res Commun; 1994 Oct 14; 204(1):399-406. PubMed ID: 7524501
    [Abstract] [Full Text] [Related]

  • 4. Insulin-induced activation of phosphatidylinositol (PI) 3-kinase. Insulin-induced phosphorylation of insulin receptors and insulin receptor substrate-1 displaces phosphorylated platelet-derived growth factor receptors from binding sites on PI 3-kinase.
    Levy-Toledano R, Blaettler DH, LaRochelle WJ, Taylor SI.
    J Biol Chem; 1995 Dec 15; 270(50):30018-22. PubMed ID: 8530404
    [Abstract] [Full Text] [Related]

  • 5. Biological function of PDGF-induced PI-3 kinase activity: its role in alpha PDGF receptor-mediated mitogenic signaling.
    Yu JC, Gutkind JS, Mahadevan D, Li W, Meyers KA, Pierce JH, Heidaran MA.
    J Cell Biol; 1994 Oct 15; 127(2):479-87. PubMed ID: 7929590
    [Abstract] [Full Text] [Related]

  • 6. Differences in substrate specificities of alpha and beta platelet-derived growth factor (PDGF) receptors. Correlation with their ability to mediate PDGF transforming functions.
    Heidaran MA, Beeler JF, Yu JC, Ishibashi T, LaRochelle WJ, Pierce JH, Aaronson SA.
    J Biol Chem; 1993 May 05; 268(13):9287-95. PubMed ID: 8387491
    [Abstract] [Full Text] [Related]

  • 7. Platelet-derived growth factor stimulates sodium-dependent Pi transport in osteoblastic cells via phospholipase Cgamma and phosphatidylinositol 3' -kinase.
    Zhen X, Bonjour JP, Caverzasio J.
    J Bone Miner Res; 1997 Jan 05; 12(1):36-44. PubMed ID: 9240723
    [Abstract] [Full Text] [Related]

  • 8. Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes.
    Navé BT, Haigh RJ, Hayward AC, Siddle K, Shepherd PR.
    Biochem J; 1996 Aug 15; 318 ( Pt 1)(Pt 1):55-60. PubMed ID: 8761452
    [Abstract] [Full Text] [Related]

  • 9. Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor.
    Nishimura R, Li W, Kashishian A, Mondino A, Zhou M, Cooper J, Schlessinger J.
    Mol Cell Biol; 1993 Nov 15; 13(11):6889-96. PubMed ID: 7692233
    [Abstract] [Full Text] [Related]

  • 10. PDGF-mediated activation of phosphatidylinositol 3 kinase in human mesangial cells.
    Choudhury GG, Biswas P, Grandaliano G, Fouqueray B, Harvey SA, Abboud HE.
    Kidney Int; 1994 Jul 15; 46(1):37-47. PubMed ID: 7933847
    [Abstract] [Full Text] [Related]

  • 11. Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin.
    Rankin S, Hooshmand-Rad R, Claesson-Welsh L, Rozengurt E.
    J Biol Chem; 1996 Mar 29; 271(13):7829-34. PubMed ID: 8631827
    [Abstract] [Full Text] [Related]

  • 12. Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors.
    Hu P, Margolis B, Skolnik EY, Lammers R, Ullrich A, Schlessinger J.
    Mol Cell Biol; 1992 Mar 29; 12(3):981-90. PubMed ID: 1372091
    [Abstract] [Full Text] [Related]

  • 13. Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells.
    Kavanaugh WM, Klippel A, Escobedo JA, Williams LT.
    Mol Cell Biol; 1992 Aug 29; 12(8):3415-24. PubMed ID: 1321334
    [Abstract] [Full Text] [Related]

  • 14. Effects of growth factors on phosphatidylinositol-3 kinase in astroglial cells.
    Pomerance M, Gavaret JM, Breton M, Pierre M.
    J Neurosci Res; 1995 Apr 15; 40(6):737-46. PubMed ID: 7543159
    [Abstract] [Full Text] [Related]

  • 15. Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton.
    Kapeller R, Chakrabarti R, Cantley L, Fay F, Corvera S.
    Mol Cell Biol; 1993 Oct 15; 13(10):6052-63. PubMed ID: 8413207
    [Abstract] [Full Text] [Related]

  • 16. Tyrosine 508 of the 85-kilodalton subunit of phosphatidylinositol 3-kinase is phosphorylated by the platelet-derived growth factor receptor.
    Kavanaugh WM, Turck CW, Klippel A, Williams LT.
    Biochemistry; 1994 Sep 13; 33(36):11046-50. PubMed ID: 8086421
    [Abstract] [Full Text] [Related]

  • 17. Common and distinct elements in insulin and PDGF signaling.
    Myers MG, Cheatham B, Fisher TL, Jachna BR, Kahn CR, Backer JM, White MF.
    Ann N Y Acad Sci; 1995 Sep 07; 766():369-87. PubMed ID: 7486683
    [Abstract] [Full Text] [Related]

  • 18. Cross-talk between the platelet-derived growth factor and the insulin signaling pathways in 3T3-L1 adipocytes.
    Ricort JM, Tanti JF, Van Obberghen E, Le Marchand-Brustel Y.
    J Biol Chem; 1997 Aug 08; 272(32):19814-8. PubMed ID: 9242642
    [Abstract] [Full Text] [Related]

  • 19. Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo.
    Domin J, Dhand R, Waterfield MD.
    J Biol Chem; 1996 Aug 30; 271(35):21614-21. PubMed ID: 8702949
    [Abstract] [Full Text] [Related]

  • 20. CAAX peptidomimetic FTI-244 decreases platelet-derived growth factor receptor tyrosine phosphorylation levels and inhibits stimulation of phosphatidylinositol 3-kinase but not mitogen-activated protein kinase.
    McGuire TF, Qian Y, Blaskovich MA, Fossum RD, Sun J, Marlowe T, Corey SJ, Wathen SP, Vogt A, Hamilton AD.
    Biochem Biophys Res Commun; 1995 Sep 05; 214(1):295-303. PubMed ID: 7669049
    [Abstract] [Full Text] [Related]

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