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266 related items for PubMed ID: 7694891

  • 1. Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates.
    Barakat RR, Li WW, Lovelace C, Bertino JR.
    Gynecol Oncol; 1993 Oct; 51(1):54-60. PubMed ID: 7694891
    [Abstract] [Full Text] [Related]

  • 2. Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug.
    Pizzorno G, Chang YM, McGuire JJ, Bertino JR.
    Cancer Res; 1989 Oct 01; 49(19):5275-80. PubMed ID: 2475246
    [Abstract] [Full Text] [Related]

  • 3. Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate.
    Curt GA, Jolivet J, Carney DN, Bailey BD, Drake JC, Clendeninn NJ, Chabner BA.
    J Clin Invest; 1985 Oct 01; 76(4):1323-9. PubMed ID: 2414316
    [Abstract] [Full Text] [Related]

  • 4. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J, Chabner BA.
    J Clin Invest; 1983 Sep 01; 72(3):773-8. PubMed ID: 6193143
    [Abstract] [Full Text] [Related]

  • 5. Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells.
    Chen G, Wright JE, Rosowsky A.
    Mol Pharmacol; 1995 Oct 01; 48(4):758-65. PubMed ID: 7476904
    [Abstract] [Full Text] [Related]

  • 6. Intrinsic resistance to methotrexate in human soft tissue sarcoma cell lines.
    Li WW, Lin JT, Schweitzer BI, Tong WP, Niedzwiecki D, Bertino JR.
    Cancer Res; 1992 Jul 15; 52(14):3908-13. PubMed ID: 1377601
    [Abstract] [Full Text] [Related]

  • 7. Biochemical and pharmacologic rationale for high-dose methotrexate.
    Jolivet J.
    NCI Monogr; 1987 Jul 15; (5):61-5. PubMed ID: 2448656
    [Abstract] [Full Text] [Related]

  • 8. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS, Galivan J, Wright JE, Rosowsky A.
    Mol Pharmacol; 1994 Apr 15; 45(4):783-91. PubMed ID: 7514264
    [Abstract] [Full Text] [Related]

  • 9. Antitumor activity of antifolate inhibitors of thymidylate and purine synthesis in human soft tissue sarcoma cell lines with intrinsic resistance to methotrexate.
    Li WW, Tong WP, Bertino JR.
    Clin Cancer Res; 1995 Jun 15; 1(6):631-6. PubMed ID: 9816025
    [Abstract] [Full Text] [Related]

  • 10. Phenotypic heterogeneity in cultured human head and neck squamous cell carcinoma lines with low-level methotrexate resistance.
    Rosowsky A, Wright JE, Cucchi CA, Lippke JA, Tantravahi R, Ervin TJ, Frei E.
    Cancer Res; 1985 Dec 15; 45(12 Pt 1):6205-12. PubMed ID: 2415240
    [Abstract] [Full Text] [Related]

  • 11. Collateral methotrexate resistance in cultured human head and neck carcinoma cells selected for resistance to cis-diamminedichloroplatinum(II).
    Rosowsky A, Wright JE, Cucchi CA, Flatow JL, Trites DH, Teicher BA, Frei E.
    Cancer Res; 1987 Nov 15; 47(22):5913-8. PubMed ID: 3664492
    [Abstract] [Full Text] [Related]

  • 12. Impaired polyglutamylation of methotrexate as a cause of resistance in CCRF-CEM cells after short-term, high-dose treatment with this drug.
    Pizzorno G, Mini E, Coronnello M, McGuire JJ, Moroson BA, Cashmore AR, Dreyer RN, Lin JT, Mazzei T, Periti P.
    Cancer Res; 1988 Apr 15; 48(8):2149-55. PubMed ID: 2450647
    [Abstract] [Full Text] [Related]

  • 13. Role of methotrexate polyglutamates in methotrexate- and sequential methotrexate-5-fluorouracil-mediated cell kill.
    McGuire JJ, Mini E, Hsieh P, Bertino JR.
    Cancer Res; 1985 Dec 15; 45(12 Pt 1):6395-400. PubMed ID: 2415244
    [Abstract] [Full Text] [Related]

  • 14. [Primary study on establishment of namalwa 12/MTX resistant cell strain and its mechanism].
    Chen J, Gu LJ, Ying DM, Shen M, Wu HJ.
    Ai Zheng; 2002 Dec 15; 21(12):1335-40. PubMed ID: 12520743
    [Abstract] [Full Text] [Related]

  • 15. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
    Diddens H, Niethammer D, Jackson RC.
    Cancer Res; 1983 Nov 15; 43(11):5286-92. PubMed ID: 6225514
    [Abstract] [Full Text] [Related]

  • 16. Biochemical and growth inhibitory effects of the erythro and threo isomers of gamma-fluoromethotrexate, a methotrexate analogue defective in polyglutamylation.
    McGuire JJ, Graber M, Licato N, Vincenz C, Coward JK, Nimec Z, Galivan J.
    Cancer Res; 1989 Aug 15; 49(16):4517-25. PubMed ID: 2472880
    [Abstract] [Full Text] [Related]

  • 17. Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.
    Koizumi S, Curt GA, Fine RL, Griffin JD, Chabner BA.
    J Clin Invest; 1985 Mar 15; 75(3):1008-14. PubMed ID: 2579975
    [Abstract] [Full Text] [Related]

  • 18. A comparison of dihydrofolate reductase activity in intact leukemia cells and squamous cell carcinoma.
    FitzGerald GB, Wick MM.
    Anticancer Drug Des; 1989 Jun 15; 4(1):79-87. PubMed ID: 2757754
    [Abstract] [Full Text] [Related]

  • 19. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
    Longo GS, Gorlick R, Tong WP, Lin S, Steinherz P, Bertino JR.
    Oncol Res; 1997 Jun 15; 9(5):259-63. PubMed ID: 9306433
    [Abstract] [Full Text] [Related]

  • 20. Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates.
    Goldman ID, Matherly LH.
    NCI Monogr; 1987 Jun 15; (5):17-26. PubMed ID: 2448654
    [Abstract] [Full Text] [Related]

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