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Journal Abstract Search

236 related items for PubMed ID: 7695913

  • 1. Generation of amyloid beta protein from its precursor is sequence specific.
    Citron M, Teplow DB, Selkoe DJ.
    Neuron; 1995 Mar; 14(3):661-70. PubMed ID: 7695913
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.
    Thinakaran G, Teplow DB, Siman R, Greenberg B, Sisodia SS.
    J Biol Chem; 1996 Apr 19; 271(16):9390-7. PubMed ID: 8621605
    [Abstract] [Full Text] [Related]

  • 3. The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway.
    Haass C, Lemere CA, Capell A, Citron M, Seubert P, Schenk D, Lannfelt L, Selkoe DJ.
    Nat Med; 1995 Dec 19; 1(12):1291-6. PubMed ID: 7489411
    [Abstract] [Full Text] [Related]

  • 4. Cathepsin D displays in vitro beta-secretase-like specificity.
    Chevallier N, Vizzavona J, Marambaud P, Baur CP, Spillantini M, Fulcrand P, Martinez J, Goedert M, Vincent JP, Checler F.
    Brain Res; 1997 Mar 07; 750(1-2):11-9. PubMed ID: 9098524
    [Abstract] [Full Text] [Related]

  • 5. Characterization of beta-amyloid peptide precursor processing by the yeast Yap3 and Mkc7 proteases.
    Zhang W, Espinoza D, Hines V, Innis M, Mehta P, Miller DL.
    Biochim Biophys Acta; 1997 Nov 27; 1359(2):110-22. PubMed ID: 9409808
    [Abstract] [Full Text] [Related]

  • 6. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
    Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M.
    Science; 1999 Oct 22; 286(5440):735-41. PubMed ID: 10531052
    [Abstract] [Full Text] [Related]

  • 7. Characterization of beta-secretase.
    Stephens DJ, Austen BM.
    Biochem Soc Trans; 1998 Aug 22; 26(3):500-4. PubMed ID: 9765904
    [No Abstract] [Full Text] [Related]

  • 8. Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein.
    McConlogue L, Castellano F, deWit C, Schenk D, Maltese WA.
    J Biol Chem; 1996 Jan 19; 271(3):1343-8. PubMed ID: 8576122
    [Abstract] [Full Text] [Related]

  • 9. beta-site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide.
    Paganetti P, Calanca V, Galli C, Stefani M, Molinari M.
    J Cell Biol; 2005 Mar 14; 168(6):863-8. PubMed ID: 15767460
    [Abstract] [Full Text] [Related]

  • 10. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
    Farzan M, Schnitzler CE, Vasilieva N, Leung D, Choe H.
    Proc Natl Acad Sci U S A; 2000 Aug 15; 97(17):9712-7. PubMed ID: 10931940
    [Abstract] [Full Text] [Related]

  • 11. Evaluation of cathepsins D and G and EC 3.4.24.15 as candidate beta-secretase proteases using peptide and amyloid precursor protein substrates.
    Brown AM, Tummolo DM, Spruyt MA, Jacobsen JS, Sonnenberg-Reines J.
    J Neurochem; 1996 Jun 15; 66(6):2436-45. PubMed ID: 8632167
    [Abstract] [Full Text] [Related]

  • 12. Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain.
    Furukawa K, Sopher BL, Rydel RE, Begley JG, Pham DG, Martin GM, Fox M, Mattson MP.
    J Neurochem; 1996 Nov 15; 67(5):1882-96. PubMed ID: 8863493
    [Abstract] [Full Text] [Related]

  • 13. The amyloid beta protein precursor mutations linked to familial Alzheimer's disease alter processing in a way that fosters amyloid deposition.
    Younkin SG.
    Tohoku J Exp Med; 1994 Nov 15; 174(3):217-23. PubMed ID: 7761987
    [Abstract] [Full Text] [Related]

  • 14. Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.
    Cai XD, Golde TE, Younkin SG.
    Science; 1993 Jan 22; 259(5094):514-6. PubMed ID: 8424174
    [Abstract] [Full Text] [Related]

  • 15. Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities.
    Citron M, Diehl TS, Gordon G, Biere AL, Seubert P, Selkoe DJ.
    Proc Natl Acad Sci U S A; 1996 Nov 12; 93(23):13170-5. PubMed ID: 8917563
    [Abstract] [Full Text] [Related]

  • 16. Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity.
    Beher D, Wrigley JD, Owens AP, Shearman MS.
    J Neurochem; 2002 Aug 12; 82(3):563-75. PubMed ID: 12153480
    [Abstract] [Full Text] [Related]

  • 17. The molecular pathology of amyloid deposition in Alzheimer's disease.
    Martins RN, Robinson PJ, Chleboun JO, Beyreuther K, Masters CL.
    Mol Neurobiol; 1991 Aug 12; 5(2-4):389-98. PubMed ID: 1823142
    [No Abstract] [Full Text] [Related]

  • 18. Processing and secretion of Alzheimer's disease amyloid precursor protein.
    Kinbara K, Kitagaki H, Kinouchi T, Okano M, Sorimachi H, Ishiura S, Suzuki K.
    Tohoku J Exp Med; 1994 Nov 12; 174(3):209-16. PubMed ID: 7761986
    [Abstract] [Full Text] [Related]

  • 19. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
    Yan R, Bienkowski MJ, Shuck ME, Miao H, Tory MC, Pauley AM, Brashier JR, Stratman NC, Mathews WR, Buhl AE, Carter DB, Tomasselli AG, Parodi LA, Heinrikson RL, Gurney ME.
    Nature; 1999 Dec 02; 402(6761):533-7. PubMed ID: 10591213
    [Abstract] [Full Text] [Related]

  • 20. Employing a superior BACE1 cleavage sequence to probe cellular APP processing.
    Tomasselli AG, Qahwash I, Emmons TL, Lu Y, Leone JW, Lull JM, Fok KF, Bannow CA, Smith CW, Bienkowski MJ, Heinrikson RL, Yan R.
    J Neurochem; 2003 Mar 02; 84(5):1006-17. PubMed ID: 12603825
    [Abstract] [Full Text] [Related]

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