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190 related items for PubMed ID: 7717849

  • 1. Metabolism of a glucuronide conjugate of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats.
    Atawodi SE, Michelsen K, Richter E.
    Arch Toxicol; 1994; 69(1):14-7. PubMed ID: 7717849
    [Abstract] [Full Text] [Related]

  • 2. Characterization of a glucuronide metabolite of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and its dose-dependent excretion in the urine of mice and rats.
    Morse MA, Eklind KI, Toussaint M, Amin SG, Chung FL.
    Carcinogenesis; 1990 Oct; 11(10):1819-23. PubMed ID: 2208595
    [Abstract] [Full Text] [Related]

  • 3. Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Carmella SG, Borukhova A, Akerkar SA, Hecht SS.
    Cancer Epidemiol Biomarkers Prev; 1997 Feb; 6(2):113-20. PubMed ID: 9037562
    [Abstract] [Full Text] [Related]

  • 4. The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.
    Brown BG, Richter E, Tricker AR, Ayres PH, Doolittle DJ.
    Chem Biol Interact; 2001 Nov 28; 138(2):125-35. PubMed ID: 11672696
    [Abstract] [Full Text] [Related]

  • 5. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
    Upadhyaya P, Kenney PM, Hochalter JB, Wang M, Hecht SS.
    Carcinogenesis; 1999 Aug 28; 20(8):1577-82. PubMed ID: 10426810
    [Abstract] [Full Text] [Related]

  • 6. Biotransformation and transport of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in bile duct-cannulated wild-type and Mrp2/Abcc2-deficient (TR ) Wistar rats.
    Leslie EM, Ghibellini G, Nezasa K, Brouwer KL.
    Carcinogenesis; 2007 Dec 28; 28(12):2650-6. PubMed ID: 17724374
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the patas monkey: pharmacokinetics and characterization of glucuronide metabolites.
    Hecht SS, Trushin N, Reid-Quinn CA, Burak ES, Jones AB, Southers JL, Gombar CT, Carmella SG, Anderson LM, Rice JM.
    Carcinogenesis; 1993 Feb 28; 14(2):229-36. PubMed ID: 8435864
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  • 12. Disposition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in bile duct-cannulated rats: stereoselective metabolism and tissue distribution.
    Wu Z, Upadhyaya P, Carmella SG, Hecht SS, Zimmerman CL.
    Carcinogenesis; 2002 Jan 28; 23(1):171-9. PubMed ID: 11756238
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  • 13. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E, Engl J, Friesenegger S, Tricker AR.
    Chem Res Toxicol; 2009 Jun 28; 22(6):1008-17. PubMed ID: 19408892
    [Abstract] [Full Text] [Related]

  • 14. Formation of NADP(H) analogs of tobacco-specific nitrosamines in rat liver and pancreatic microsomes.
    Peterson LA, Ng DK, Stearns RA, Hecht SS.
    Chem Res Toxicol; 1994 Jun 28; 7(5):599-608. PubMed ID: 7841337
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  • 15. Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Zhang S, Wang M, Villalta PW, Lindgren BR, Upadhyaya P, Lao Y, Hecht SS.
    Chem Res Toxicol; 2009 May 28; 22(5):926-36. PubMed ID: 19358518
    [Abstract] [Full Text] [Related]

  • 16. Stereoselective metabolism and tissue retention in rats of the individual enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Zimmerman CL, Wu Z, Upadhyaya P, Hecht SS.
    Carcinogenesis; 2004 Jul 28; 25(7):1237-42. PubMed ID: 14988218
    [Abstract] [Full Text] [Related]

  • 17. Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.
    Doerr-O'Rourke K, Trushin N, Hecht SS, Stoner GD.
    Carcinogenesis; 1991 Jun 28; 12(6):1029-34. PubMed ID: 2044181
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  • 18. The profile of urinary metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats is determined by its pulmonary metabolism.
    Schneider T, Frei E, Wiessler M.
    Chem Biol Interact; 1999 Apr 15; 118(3):247-66. PubMed ID: 10362230
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  • 19. Cell specificity for the pulmonary metabolism of tobacco-specific nitrosamines in the Fischer rat.
    Belinsky SA, White CM, Trushin N, Hecht SS.
    Carcinogenesis; 1989 Dec 15; 10(12):2269-74. PubMed ID: 2591016
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  • 20. Effects of phenobarbital and 3-methylcholanthrene induction on the formation of three glucuronide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, NNK.
    Murphy SE, Nunes MG, Hatala MA.
    Chem Biol Interact; 1997 Mar 14; 103(3):153-66. PubMed ID: 9134006
    [Abstract] [Full Text] [Related]


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