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371 related items for PubMed ID: 7726551

  • 1. Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway.
    Farh L, Mitchell DA, Deschenes RJ.
    Arch Biochem Biophys; 1995 Apr 01; 318(1):113-21. PubMed ID: 7726551
    [Abstract] [Full Text] [Related]

  • 2. Functional consequence of mutating conserved residues of the yeast farnesyl-protein transferase beta-subunit Ram1(Dpr1).
    Kurth DD, Farh L, Deschenes RJ.
    Biochemistry; 1997 Dec 16; 36(50):15932-9. PubMed ID: 9398327
    [Abstract] [Full Text] [Related]

  • 3. C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins.
    Gillespie JR, Yokoyama K, Lu K, Eastman RT, Bollinger JG, Van Voorhis WC, Gelb MH, Buckner FS.
    Mol Biochem Parasitol; 2007 Jun 16; 153(2):115-24. PubMed ID: 17397944
    [Abstract] [Full Text] [Related]

  • 4. RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins.
    He B, Chen P, Chen SY, Vancura KL, Michaelis S, Powers S.
    Proc Natl Acad Sci U S A; 1991 Dec 15; 88(24):11373-7. PubMed ID: 1763050
    [Abstract] [Full Text] [Related]

  • 5. Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins.
    Goodman LE, Judd SR, Farnsworth CC, Powers S, Gelb MH, Glomset JA, Tamanoi F.
    Proc Natl Acad Sci U S A; 1990 Dec 15; 87(24):9665-9. PubMed ID: 2124698
    [Abstract] [Full Text] [Related]

  • 6. Disrupting the transforming activity of shrimp ras(Q(61)K) by deleting the CAAX box at the C-terminus.
    Huang CF, Chen CH, Chuang NN.
    J Exp Zool; 2001 Jun 01; 289(7):441-8. PubMed ID: 11351331
    [Abstract] [Full Text] [Related]

  • 7. A polybasic domain allows nonprenylated Ras proteins to function in Saccharomyces cerevisiae.
    Mitchell DA, Farh L, Marshall TK, Deschenes RJ.
    J Biol Chem; 1994 Aug 26; 269(34):21540-6. PubMed ID: 8063791
    [Abstract] [Full Text] [Related]

  • 8. Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae.
    Trueblood CE, Ohya Y, Rine J.
    Mol Cell Biol; 1993 Jul 26; 13(7):4260-75. PubMed ID: 8321228
    [Abstract] [Full Text] [Related]

  • 9. Sequence dependence of protein isoprenylation.
    Moores SL, Schaber MD, Mosser SD, Rands E, O'Hara MB, Garsky VM, Marshall MS, Pompliano DL, Gibbs JB.
    J Biol Chem; 1991 Aug 05; 266(22):14603-10. PubMed ID: 1860864
    [Abstract] [Full Text] [Related]

  • 10. RhoB prenylation is driven by the three carboxyl-terminal amino acids of the protein: evidenced in vivo by an anti-farnesyl cysteine antibody.
    Baron R, Fourcade E, Lajoie-Mazenc I, Allal C, Couderc B, Barbaras R, Favre G, Faye JC, Pradines A.
    Proc Natl Acad Sci U S A; 2000 Oct 10; 97(21):11626-31. PubMed ID: 11027361
    [Abstract] [Full Text] [Related]

  • 11. Farnesylation of p21 Ras proteins in Xenopus oocytes.
    Zhao J, Kung HF, Manne V.
    Cell Mol Biol Res; 1994 Oct 10; 40(4):313-21. PubMed ID: 7866432
    [Abstract] [Full Text] [Related]

  • 12. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
    Reid TS, Terry KL, Casey PJ, Beese LS.
    J Mol Biol; 2004 Oct 15; 343(2):417-33. PubMed ID: 15451670
    [Abstract] [Full Text] [Related]

  • 13. Plant farnesyltransferase can restore yeast Ras signaling and mating.
    Yalovsky S, Trueblood CE, Callan KL, Narita JO, Jenkins SM, Rine J, Gruissem W.
    Mol Cell Biol; 1997 Apr 15; 17(4):1986-94. PubMed ID: 9121446
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines.
    Lerner EC, Zhang TT, Knowles DB, Qian Y, Hamilton AD, Sebti SM.
    Oncogene; 1997 Sep 15; 15(11):1283-8. PubMed ID: 9315095
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of non-peptide Ras CAAX mimetics as potent farnesyltransferase inhibitors.
    Qian Y, Vogt A, Sebti SM, Hamilton AD.
    J Med Chem; 1996 Jan 05; 39(1):217-23. PubMed ID: 8568811
    [Abstract] [Full Text] [Related]

  • 16. Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.
    Finegold AA, Johnson DI, Farnsworth CC, Gelb MH, Judd SR, Glomset JA, Tamanoi F.
    Proc Natl Acad Sci U S A; 1991 May 15; 88(10):4448-52. PubMed ID: 2034682
    [Abstract] [Full Text] [Related]

  • 17. Site-directed mutations altering the CAAX box of Ste18, the yeast pheromone-response pathway G gamma subunit.
    Whiteway MS, Thomas DY.
    Genetics; 1994 Aug 15; 137(4):967-76. PubMed ID: 7982577
    [Abstract] [Full Text] [Related]

  • 18. Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae.
    Dong X, Mitchell DA, Lobo S, Zhao L, Bartels DJ, Deschenes RJ.
    Mol Cell Biol; 2003 Sep 15; 23(18):6574-84. PubMed ID: 12944483
    [Abstract] [Full Text] [Related]

  • 19. Enzymology and biology of CaaX protein prenylation.
    Fu HW, Casey PJ.
    Recent Prog Horm Res; 1999 Sep 15; 54():315-42; discussion 342-3. PubMed ID: 10548882
    [Abstract] [Full Text] [Related]

  • 20. Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export.
    Sapperstein S, Berkower C, Michaelis S.
    Mol Cell Biol; 1994 Feb 15; 14(2):1438-49. PubMed ID: 8289819
    [Abstract] [Full Text] [Related]

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