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241 related items for PubMed ID: 7728953

  • 1. Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action.
    Grdina DJ, Shigematsu N, Dale P, Newton GL, Aguilera JA, Fahey RC.
    Carcinogenesis; 1995 Apr; 16(4):767-74. PubMed ID: 7728953
    [Abstract] [Full Text] [Related]

  • 2. Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278).
    Shigematsu N, Schwartz JL, Grdina DJ.
    Mutagenesis; 1994 Jul; 9(4):355-60. PubMed ID: 7968578
    [Abstract] [Full Text] [Related]

  • 3. Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine.
    Liu SC, Murley JS, Woloschak G, Grdina DJ.
    Carcinogenesis; 1997 Dec; 18(12):2457-9. PubMed ID: 9450496
    [Abstract] [Full Text] [Related]

  • 4. Promotion of cystine uptake, increase of glutathione biosynthesis, and modulation of glutathione status by S-2-(3-aminopropylamino)ethyl phosphorothioic acid (WR-2721) in Chinese hamster cells.
    Issels RD, Nagele A.
    Cancer Res; 1989 Apr 15; 49(8):2082-6. PubMed ID: 2539252
    [Abstract] [Full Text] [Related]

  • 5. Radiation response of cells during altered protein thiol redox.
    Biaglow JE, Ayene IS, Koch CJ, Donahue J, Stamato TD, Mieyal JJ, Tuttle SW.
    Radiat Res; 2003 Apr 15; 159(4):484-94. PubMed ID: 12643793
    [Abstract] [Full Text] [Related]

  • 6. Uptake of WR-2721 derivatives by cells in culture: identification of the transported form of the drug.
    Calabro-Jones PM, Aguilera JA, Ward JF, Smoluk GD, Fahey RC.
    Cancer Res; 1988 Jul 01; 48(13):3634-40. PubMed ID: 2837319
    [Abstract] [Full Text] [Related]

  • 7. The inhibition of radiation-induced mutagenesis by the combined effects of selenium and the aminothiol WR-1065.
    Diamond AM, Dale P, Murray JL, Grdina DJ.
    Mutat Res; 1996 Sep 23; 356(2):147-54. PubMed ID: 8841479
    [Abstract] [Full Text] [Related]

  • 8. Chemical protection and cell-cycle effects on radiation-induced mutagenesis.
    Grdina DJ, Sigdestad CP.
    Cell Prolif; 1992 Jan 23; 25(1):23-9. PubMed ID: 1540681
    [Abstract] [Full Text] [Related]

  • 9. Dimethyl sulfoxide protects against thermal and epithermal neutron-induced cell death and mutagenesis of Chinese hamster ovary (CHO) cells.
    Kinashi Y, Sakurai Y, Masunaga S, Suzuki M, Akaboshi M, Ono K.
    Int J Radiat Oncol Biol Phys; 2000 Jul 15; 47(5):1371-8. PubMed ID: 10889392
    [Abstract] [Full Text] [Related]

  • 10. Anticlastogenic effect of S-2-(3-aminopropylamino) ethylphosphorothioic acid against X-rays in mice.
    Mazur L.
    Physiol Res; 1996 Jul 15; 45(1):59-63. PubMed ID: 8884925
    [Abstract] [Full Text] [Related]

  • 11. WR-2721 (amifostine) infusion in patients with Ewing's sarcoma receiving ifosfamide and cyclophosphamide with mesna: drug and thiol levels in plasma and blood cells, a Pediatric Oncology Group study.
    Souid AK, Fahey RC, Dubowy RL, Newton GL, Bernstein ML.
    Cancer Chemother Pharmacol; 1999 Jul 15; 44(6):498-504. PubMed ID: 10550571
    [Abstract] [Full Text] [Related]

  • 12. Antimutagenic effects of radioprotector WR-2721 against fission-spectrum neurons and 60Co gamma-rays in mice.
    Kataoka Y, Basic I, Perrin J, Grdina DJ.
    Int J Radiat Biol; 1992 Mar 15; 61(3):387-92. PubMed ID: 1347072
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and antiproliferative activities of doxorubicin thiol conjugates and doxorubicin-SS-cyclic peptide.
    Darwish S, Sadeghiani N, Fong S, Mozaffari S, Hamidi P, Withana T, Yang S, Tiwari RK, Parang K.
    Eur J Med Chem; 2019 Jan 01; 161():594-606. PubMed ID: 30396106
    [Abstract] [Full Text] [Related]

  • 14. Pharmacokinetic profile of amifostine.
    Shaw LM, Bonner H, Lieberman R.
    Semin Oncol; 1996 Aug 01; 23(4 Suppl 8):18-22. PubMed ID: 8783662
    [Abstract] [Full Text] [Related]

  • 15. Metabolic pathways of WR-2721 (ethyol, amifostine) in the BALB/c mouse.
    Shaw LM, Bonner HS, Brown DQ.
    Drug Metab Dispos; 1994 Aug 01; 22(6):895-902. PubMed ID: 7895607
    [Abstract] [Full Text] [Related]

  • 16. Binding of radioprotective thiols and disulfides in Chinese hamster V79 cell nuclei.
    Newton GL, Aguilera JA, Ward JF, Fahey RC.
    Radiat Res; 1996 Sep 01; 146(3):298-305. PubMed ID: 8752308
    [Abstract] [Full Text] [Related]

  • 17. Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs.
    Murley JS, Kataoka Y, Cao D, Li JJ, Oberley LW, Grdina DJ.
    Radiat Res; 2004 Nov 01; 162(5):536-46. PubMed ID: 15624308
    [Abstract] [Full Text] [Related]

  • 18. The effects of antioxidants and enzymes involved in glutathione metabolism on mutagenesis by glutathione and L-cysteine.
    Stark AA, Pagano DA, Glass G, Kamin-Belsky N, Zeiger E.
    Mutat Res; 1994 Jul 16; 308(2):215-22. PubMed ID: 7518048
    [Abstract] [Full Text] [Related]

  • 19. The radioprotective agent, amifostine, suppresses the reactivity of intralysosomal iron.
    Yu Z, Eaton JW, Persson HL.
    Redox Rep; 2003 Jul 16; 8(6):347-55. PubMed ID: 14980067
    [Abstract] [Full Text] [Related]

  • 20. Effects of GSH and WR-2721 on induction of micronuclei by cyclophosphamide.
    Mazur L, Bławat A.
    Toxicol Lett; 1999 Oct 29; 110(1-2):67-72. PubMed ID: 10593596
    [Abstract] [Full Text] [Related]

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