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Journal Abstract Search


202 related items for PubMed ID: 7731962

  • 1. Use of binding energy by an RNA enzyme for catalysis by positioning and substrate destabilization.
    Narlikar GJ, Gopalakrishnan V, McConnell TS, Usman N, Herschlag D.
    Proc Natl Acad Sci U S A; 1995 Apr 25; 92(9):3668-72. PubMed ID: 7731962
    [Abstract] [Full Text] [Related]

  • 2. Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA.
    Herschlag D, Eckstein F, Cech TR.
    Biochemistry; 1993 Aug 17; 32(32):8299-311. PubMed ID: 7688572
    [Abstract] [Full Text] [Related]

  • 3. The tetrahymena ribozyme cleaves a 5'-methylene phosphonate monoester approximately 10(2)-fold faster than a normal phosphate diester: implications for enzyme catalysis of phosphoryl transfer reactions.
    Liao X, Anjaneyulu PS, Curley JF, Hsu M, Boehringer M, Caruthers MH, Piccirilli JA.
    Biochemistry; 2001 Sep 18; 40(37):10911-26. PubMed ID: 11551186
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  • 4. The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction.
    Herschlag D, Eckstein F, Cech TR.
    Biochemistry; 1993 Aug 17; 32(32):8312-21. PubMed ID: 7688573
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  • 5. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site.
    Herschlag D, Cech TR.
    Biochemistry; 1990 Nov 06; 29(44):10159-71. PubMed ID: 2271645
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  • 7. Leaving group stabilization by metal ion coordination and hydrogen bond donation is an evolutionarily conserved feature of group I introns.
    Kuo LY, Piccirilli JA.
    Biochim Biophys Acta; 2001 Dec 30; 1522(3):158-66. PubMed ID: 11779630
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  • 8. Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction.
    Shan S, Kravchuk AV, Piccirilli JA, Herschlag D.
    Biochemistry; 2001 May 01; 40(17):5161-71. PubMed ID: 11318638
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  • 11. Protonated 2'-aminoguanosine as a probe of the electrostatic environment of the active site of the Tetrahymena group I ribozyme.
    Shan SO, Narlikar GJ, Herschlag D.
    Biochemistry; 1999 Aug 24; 38(34):10976-88. PubMed ID: 10460152
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  • 12. A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site.
    Forconi M, Sengupta RN, Piccirilli JA, Herschlag D.
    Biochemistry; 2010 Mar 30; 49(12):2753-62. PubMed ID: 20175542
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  • 13. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site.
    Herschlag D, Cech TR.
    Biochemistry; 1990 Nov 06; 29(44):10172-80. PubMed ID: 2271646
    [Abstract] [Full Text] [Related]

  • 14. Probing the role of metal ions in RNA catalysis: kinetic and thermodynamic characterization of a metal ion interaction with the 2'-moiety of the guanosine nucleophile in the Tetrahymena group I ribozyme.
    Shan SO, Herschlag D.
    Biochemistry; 1999 Aug 24; 38(34):10958-75. PubMed ID: 10460151
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  • 15. Metal ion catalysis in the Tetrahymena ribozyme reaction.
    Piccirilli JA, Vyle JS, Caruthers MH, Cech TR.
    Nature; 1993 Jan 07; 361(6407):85-8. PubMed ID: 8421499
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  • 17. Dissection of the role of the conserved G.U pair in group I RNA self-splicing.
    Knitt DS, Narlikar GJ, Herschlag D.
    Biochemistry; 1994 Nov 22; 33(46):13864-79. PubMed ID: 7947795
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  • 19. Catalysis by RNase P RNA: unique features and unprecedented active site plasticity.
    Persson T, Cuzic S, Hartmann RK.
    J Biol Chem; 2003 Oct 31; 278(44):43394-401. PubMed ID: 12904300
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