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118 related items for PubMed ID: 7736927

  • 1. Contribution of oxidation and deacetylation to the bioactivation of acetaminophen in vitro in liver and kidney from male and female Sprague-Dawley rats.
    Mugford CA, Tarloff JB.
    Drug Metab Dispos; 1995 Feb; 23(2):290-4. PubMed ID: 7736927
    [Abstract] [Full Text] [Related]

  • 2. The contribution of oxidation and deacetylation to acetaminophen nephrotoxicity in female Sprague-Dawley rats.
    Mugford CA, Tarloff JB.
    Toxicol Lett; 1997 Sep 19; 93(1):15-22. PubMed ID: 9381478
    [Abstract] [Full Text] [Related]

  • 3. Sex- and age-dependent acetaminophen hepato- and nephrotoxicity in Sprague-Dawley rats: role of tissue accumulation, nonprotein sulfhydryl depletion, and covalent binding.
    Tarloff JB, Khairallah EA, Cohen SD, Goldstein RS.
    Fundam Appl Toxicol; 1996 Mar 19; 30(1):13-22. PubMed ID: 8812206
    [Abstract] [Full Text] [Related]

  • 4. Acetaminophen nephrotoxicity in the rat. Renal metabolic activation in vitro.
    Newton JF, Bailie MB, Hook JB.
    Toxicol Appl Pharmacol; 1983 Sep 30; 70(3):433-44. PubMed ID: 6636173
    [Abstract] [Full Text] [Related]

  • 5. Acetaminophen nephrotoxicity in the rat: quantitation of renal metabolic activation in vivo.
    Newton JF, Pasino DA, Hook JB.
    Toxicol Appl Pharmacol; 1985 Mar 30; 78(1):39-46. PubMed ID: 4035671
    [Abstract] [Full Text] [Related]

  • 6. The role of p-aminophenol in acetaminophen-induced nephrotoxicity: effect of bis(p-nitrophenyl) phosphate on acetaminophen and p-aminophenol nephrotoxicity and metabolism in Fischer 344 rats.
    Newton JF, Kuo CH, DeShone GM, Hoefle D, Bernstein J, Hook JB.
    Toxicol Appl Pharmacol; 1985 Dec 30; 81(3 Pt 1):416-30. PubMed ID: 4082192
    [Abstract] [Full Text] [Related]

  • 7. Enhanced nephrotoxicity of acetaminophen in fructose-induced hypertriglyceridemic rats: contribution of oxidation and deacetylation of acetaminophen to an enhancement of nephrotoxicity.
    Ishida K, Ikegami H, Doi K.
    Exp Toxicol Pathol; 1997 Dec 30; 49(5):313-9. PubMed ID: 9455675
    [Abstract] [Full Text] [Related]

  • 8. Acetaminophen nephrotoxicity in the rat. I. Strain differences in nephrotoxicity and metabolism.
    Newton JF, Yoshimoto M, Bernstein J, Rush GF, Hook JB.
    Toxicol Appl Pharmacol; 1983 Jun 30; 69(2):291-306. PubMed ID: 6868091
    [Abstract] [Full Text] [Related]

  • 9. Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse.
    Emeigh Hart SG, Beierschmitt WP, Bartolone JB, Wyand DS, Khairallah EA, Cohen SD.
    Toxicol Appl Pharmacol; 1991 Jan 30; 107(1):1-15. PubMed ID: 1987650
    [Abstract] [Full Text] [Related]

  • 10. Sex-related differences in mouse renal metabolism and toxicity of acetaminophen.
    Hu JJ, Lee MJ, Vapiwala M, Reuhl K, Thomas PE, Yang CS.
    Toxicol Appl Pharmacol; 1993 Sep 30; 122(1):16-26. PubMed ID: 8378930
    [Abstract] [Full Text] [Related]

  • 11. Gender-related differences in susceptibility to acetaminophen-induced protein arylation and nephrotoxicity in the CD-1 mouse.
    Hoivik DJ, Manautou JE, Tveit A, Hart SG, Khairallah EA, Cohen SD.
    Toxicol Appl Pharmacol; 1995 Feb 30; 130(2):257-71. PubMed ID: 7871539
    [Abstract] [Full Text] [Related]

  • 12. Coincubation of rat renal proximal tubules with hepatic subcellular fractions potentiates the effects of para-aminophenol.
    Shao R, Ring SC, Tarloff JB.
    Fundam Appl Toxicol; 1997 Oct 30; 39(2):101-8. PubMed ID: 9344622
    [Abstract] [Full Text] [Related]

  • 13. Intrinsic susceptibility of the kidney to acetaminophen toxicity in middle-aged rats.
    Tarloff JB, Goldstein RS, Silver AC, Hewitt WR, Hook JB.
    Toxicol Lett; 1990 Jun 30; 52(1):101-10. PubMed ID: 2356566
    [Abstract] [Full Text] [Related]

  • 14. Acetaminophen nephrotoxicity in CD-1 mice. I. Evidence of a role for in situ activation in selective covalent binding and toxicity.
    Hart SG, Beierschmitt WP, Wyand DS, Khairallah EA, Cohen SD.
    Toxicol Appl Pharmacol; 1994 Jun 30; 126(2):267-75. PubMed ID: 8209379
    [Abstract] [Full Text] [Related]

  • 15. Effects of fructose-induced hypertriglyceridemia on hepatorenal toxicity of acetaminophen in rats: role of pharmacokinetics and metabolism of acetaminophen.
    Ishida K, Sakazume M, Watanabe M, Hirai N, Ikegami H, Sakai T, Doi K.
    Exp Toxicol Pathol; 1997 Aug 30; 49(3-4):207-15. PubMed ID: 9314055
    [Abstract] [Full Text] [Related]

  • 16. Hepatic and renal conjugation (Phase II) enzyme activities in young adult, middle-aged, and senescent male Sprague-Dawley rats.
    Tarloff JB, Goldstein RS, Sozio RS, Hook JB.
    Proc Soc Exp Biol Med; 1991 Jul 30; 197(3):297-303. PubMed ID: 1906180
    [Abstract] [Full Text] [Related]

  • 17. Role of pharmacokinetics and metabolism in the enhanced susceptibility of middle-aged male Sprague-Dawley rats to acetaminophen nephrotoxicity.
    Tarloff JB, Goldstein RS, Mico BA, Hook JB.
    Drug Metab Dispos; 1989 Jul 30; 17(2):139-46. PubMed ID: 2565202
    [Abstract] [Full Text] [Related]

  • 18. A Cytochrome P450-Independent Mechanism of Acetaminophen-Induced Injury in Cultured Mouse Hepatocytes.
    Miyakawa K, Albee R, Letzig LG, Lehner AF, Scott MA, Buchweitz JP, James LP, Ganey PE, Roth RA.
    J Pharmacol Exp Ther; 2015 Aug 30; 354(2):230-7. PubMed ID: 26065700
    [Abstract] [Full Text] [Related]

  • 19. Acetaminophen nephrotoxicity in the rat. II. Strain differences in nephrotoxicity and metabolism of p-aminophenol, a metabolite of acetaminophen.
    Newton JF, Yoshimoto M, Bernstein J, Rush GF, Hook JB.
    Toxicol Appl Pharmacol; 1983 Jun 30; 69(2):307-18. PubMed ID: 6868092
    [Abstract] [Full Text] [Related]

  • 20. Renal damage, metabolism and covalent binding following administration of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide (NDPS) to male Fischer 344 rats.
    Henesey CM, Harvison PJ.
    Toxicology; 2002 Jan 25; 170(3):187-200. PubMed ID: 11788156
    [Abstract] [Full Text] [Related]

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