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372 related items for PubMed ID: 7746141

  • 1. Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene.
    Awad MM, Bryant AE, Stevens DL, Rood JI.
    Mol Microbiol; 1995 Jan; 15(2):191-202. PubMed ID: 7746141
    [Abstract] [Full Text] [Related]

  • 2. Synergistic effects of alpha-toxin and perfringolysin O in Clostridium perfringens-mediated gas gangrene.
    Awad MM, Ellemor DM, Boyd RL, Emmins JJ, Rood JI.
    Infect Immun; 2001 Dec; 69(12):7904-10. PubMed ID: 11705975
    [Abstract] [Full Text] [Related]

  • 3. Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum.
    Hickey MJ, Kwan RY, Awad MM, Kennedy CL, Young LF, Hall P, Cordner LM, Lyras D, Emmins JJ, Rood JI.
    PLoS Pathog; 2008 Apr 11; 4(4):e1000045. PubMed ID: 18404211
    [Abstract] [Full Text] [Related]

  • 4. Use of genetically manipulated strains of Clostridium perfringens reveals that both alpha-toxin and theta-toxin are required for vascular leukostasis to occur in experimental gas gangrene.
    Ellemor DM, Baird RN, Awad MM, Boyd RL, Rood JI, Emmins JJ.
    Infect Immun; 1999 Sep 11; 67(9):4902-7. PubMed ID: 10456947
    [Abstract] [Full Text] [Related]

  • 5. Cross-complementation of Clostridium perfringens PLC and Clostridium septicum alpha-toxin mutants reveals PLC is sufficient to mediate gas gangrene.
    Kennedy CL, Lyras D, Cheung JK, Hiscox TJ, Emmins JJ, Rood JI.
    Microbes Infect; 2009 Mar 11; 11(3):413-8. PubMed ID: 19284973
    [Abstract] [Full Text] [Related]

  • 6. Sugar inhibits the production of the toxins that trigger clostridial gas gangrene.
    Méndez MB, Goñi A, Ramirez W, Grau RR.
    Microb Pathog; 2012 Jan 11; 52(1):85-91. PubMed ID: 22079896
    [Abstract] [Full Text] [Related]

  • 7. Gas gangrene-associated gliding motility is regulated by the Clostridium perfringens CpAL/VirSR system.
    Valeriani RG, Beard LL, Moller A, Ohtani K, Vidal JE.
    Anaerobe; 2020 Dec 11; 66():102287. PubMed ID: 33130105
    [Abstract] [Full Text] [Related]

  • 8. Isolation of alpha-toxin, theta-toxin and kappa-toxin mutants of Clostridium perfringens by Tn916 mutagenesis.
    Awad MM, Rood JI.
    Microb Pathog; 1997 May 11; 22(5):275-84. PubMed ID: 9160297
    [Abstract] [Full Text] [Related]

  • 9. The Agr-Like Quorum-Sensing System Is Important for Clostridium perfringens Type A Strain ATCC 3624 To Cause Gas Gangrene in a Mouse Model.
    Navarro MA, Li J, Beingesser J, McClane BA, Uzal FA.
    mSphere; 2020 Jun 17; 5(3):. PubMed ID: 32554714
    [Abstract] [Full Text] [Related]

  • 10. Effects of Clostridium perfringens alpha-toxin (PLC) and perfringolysin O (PFO) on cytotoxicity to macrophages, on escape from the phagosomes of macrophages, and on persistence of C. perfringens in host tissues.
    O'Brien DK, Melville SB.
    Infect Immun; 2004 Sep 17; 72(9):5204-15. PubMed ID: 15322015
    [Abstract] [Full Text] [Related]

  • 11. The luxS gene is involved in cell-cell signalling for toxin production in Clostridium perfringens.
    Ohtani K, Hayashi H, Shimizu T.
    Mol Microbiol; 2002 Apr 17; 44(1):171-9. PubMed ID: 11967077
    [Abstract] [Full Text] [Related]

  • 12. Ethanolamine utilization supports Clostridium perfringens growth in infected tissues.
    Yagi H, Nakayama-Imaohji H, Nariya H, Tada A, Yamasaki H, Ugai H, Elahi M, Ono T, Kuwahara T.
    Microb Pathog; 2018 Jun 17; 119():200-207. PubMed ID: 29654901
    [Abstract] [Full Text] [Related]

  • 13. Construction and virulence testing of a collagenase mutant of Clostridium perfringens.
    Awad MM, Ellemor DM, Bryant AE, Matsushita O, Boyd RL, Stevens DL, Emmins JJ, Rood JI.
    Microb Pathog; 2000 Feb 17; 28(2):107-17. PubMed ID: 10644496
    [Abstract] [Full Text] [Related]

  • 14. Identification and molecular analysis of a locus that regulates extracellular toxin production in Clostridium perfringens.
    Lyristis M, Bryant AE, Sloan J, Awad MM, Nisbet IT, Stevens DL, Rood JI.
    Mol Microbiol; 1994 Jun 17; 12(5):761-77. PubMed ID: 8052128
    [Abstract] [Full Text] [Related]

  • 15. The cysteine protease α-clostripain is not essential for the pathogenesis of Clostridium perfringens-mediated myonecrosis.
    Chakravorty A, Awad MM, Hiscox TJ, Cheung JK, Carter GP, Choo JM, Lyras D, Rood JI.
    PLoS One; 2011 Jun 17; 6(7):e22762. PubMed ID: 21829506
    [Abstract] [Full Text] [Related]

  • 16. Enhanced production of phospholipase C and perfringolysin O (alpha and theta toxins) in a gatifloxacin-resistant strain of Clostridium perfringens.
    Rafii F, Park M, Bryant AE, Johnson SJ, Wagner RD.
    Antimicrob Agents Chemother; 2008 Mar 17; 52(3):895-900. PubMed ID: 18160514
    [Abstract] [Full Text] [Related]

  • 17. Virulence genes of Clostridium perfringens.
    Rood JI.
    Annu Rev Microbiol; 1998 Mar 17; 52():333-60. PubMed ID: 9891801
    [Abstract] [Full Text] [Related]

  • 18. Perfringolysin O expression in Clostridium perfringens is independent of the upstream pfoR gene.
    Awad MM, Rood JI.
    J Bacteriol; 2002 Apr 17; 184(7):2034-8. PubMed ID: 11889112
    [Abstract] [Full Text] [Related]

  • 19. Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model.
    Sayeed S, Uzal FA, Fisher DJ, Saputo J, Vidal JE, Chen Y, Gupta P, Rood JI, McClane BA.
    Mol Microbiol; 2008 Jan 17; 67(1):15-30. PubMed ID: 18078439
    [Abstract] [Full Text] [Related]

  • 20. Inactivation of the gene (cpe) encoding Clostridium perfringens enterotoxin eliminates the ability of two cpe-positive C. perfringens type A human gastrointestinal disease isolates to affect rabbit ileal loops.
    Sarker MR, Carman RJ, McClane BA.
    Mol Microbiol; 1999 Sep 17; 33(5):946-58. PubMed ID: 10476029
    [Abstract] [Full Text] [Related]

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